Phytochemical components and evidence of the antibacterial efficacy of Terminalia catappa leaf extracts against Staphylococcus aureus strains

Authors

DOI:

https://doi.org/10.33448/rsd-v9i11.10465

Keywords:

Microbial resistance; Staphylococcus aureus; Medicinal plants; Terminalia catappa; Phytochemical composition.

Abstract

The aim of the present study was to list the phytochemical components described in the literature of different extracts of Terminalia catappa leaves, describing those that have an antibacterial effect, as well as to evaluate evidence of the effectiveness of their antibacterial activity against strains of Staphylococcus aureus. It is an integrative review study and the research was carried out in the MEDLINE-Pubmed, SciELO and Google Scholar databases with the descriptors Terminalia catappa, Phytochemical composition and Staphylococcus aureus. A total of 9 articles published between 2015 and 2020, with full text and language in Portuguese and English, were selected. The results demonstrate that phytochemical components such as tannins, flavonoids, triterpenes, phenols and alkaloids were the most commonly found in the different extracts of T. catappa leaves. These components are responsible for a series of therapeutic effects, in particular the antibacterial effect, which is detected in tannins, flavonoids, saponins and alkaloids. In addition, there was significant efficacy in relation to the antibacterial activity of extracts of T. catappa leaves against strains of S. aureus (ATCC 25923) and methicillin-resistant S. aureus - MRSA (343602). Therefore, it is concluded that the leaves of T. catappa have a great potential to be used in the treatment of infectious diseases caused by S. aureus.

References

Allyn, O. Q., Kusumawati, E., & Nugroho, R. A. (2018). Antimicrobial activity of Terminalia catappa brown leaf extracts against Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853. F1000Research, 7, 1-9. https://doi.org/10.12688/f1000research.15998.1

Almeida, M. S. C., Mendonça, R. L., Freitas, M. Z. C., & Vandesmet, L. C. (2016). Staphylococcus aureus. Mostra Científica em Biomedicina, 1(1). Recuperado de http://publicacoesacademicas.unicatolicaquixada.edu.br/index.php/mostrabiomedicina/article/view/842

Anand, A. V., Divya, N., & Kotti, P. P. (2015). An updated review of Terminalia catappa. Pharmacognosy Reviews, 9(18), 93-98. https://doi.org/10.4103/0973-7847.162103

Brindha, P., Sasikala, B., & Purushothaman, K. K. (1981). Pharmacognostic studies on Merugan Kizhangu. Bull Med Eth Bot Res, 3, 84-96.

Chole, P., & Ravi, L. (2020). A review on medicinal potential of Terminalia catappa. International Journal of Green Pharmacy, 14(3), 229-234.

Costa, L.P.S., & Araujo, M.S.R. (2011). Documentação química e farmacológica de espécies vegetais do cerrado e caatinga piauiense. Recuperado de http://leg.ufpi.br/21sic/Documentos/RESUMOS/Modalidade/Exatas/Luis%20Paulo.pdf

Divya, N., Rengarajan, R. L., Radhakrishnan, R., Abd_Allah, E. F., Alqarawi, A. A., Hashem, A., Manikandan, R., & Anand, A. V. (2019). Phytotherapeutic efficacy of the medicinal plant Terminalia catappa L. Saudi Journal of Biological Science, 26(5), 985-988. https://doi.org/10.1016/j.sjbs.2018.12.010

Fonseca, A. M. de., Maia, A. I. V., Dias, B., Nepomuceno, F. W. A. B., Belina, M. C., & Araújo, M. R. S. de. (2019). Abordagem fitoquímica e farmacológica das folhas Terminalia catappa Linn (Combretaceae). In W. D. Guilherme (Org.), Desafios e Soluções da Sociologia 2 (pp. 15-27). Atena Editora. https://doi.org/10.22533/at.ed.2691925062

Guimarães, C. C., Ferreira, T. C., Oliveira, R. C. F. de., Simioni, P. U., & Ugrinovich, L. A. (2017). Atividade antimicrobiana in vitro do extrato aquoso e do óleo essencial do alecrim (Rosmarinus officinalis L.) e do cravo-da-índia (Caryophyllus aromaticus L.) frente a cepas de Staphylococcus aureus e Escherichia coli. Revista Brasileira de Biociências, 15(2), 83-89. Recuperado de http://www.ufrgs.br/seerbio/ojs/index.php/rbb/article/view/3877/1358

Lara, A., Trevisani, A. C., Santos, I. C. dos., Barbosa, L. N., Matta, R. da., & Gonçalves, D. D. (2019). Medicinal plants Antimicrobial Activity against Staphylococcus spp – Literature Review. Brazilian Journal of Development, 5(10), 18612-18631. https://doi.org/10.34117/bjdv5n10-111

Lima, M. F. P., Borges, M. A., Parente, R. S., Victória, R. C. Jr., & Oliveira, M. E. de. (2015). Staphylococcus aureus e as infecções hospitalares – Revisão de literatura. Revista UNINGÁ Review, 21(1), 32-39. Recuperado de http://revista.uninga.br/index.php/uningareviews/article/view/1616/1227

Lin, J., Nishino, K., Tolmasky, M., Aminov, R., & Zhang, L. (2015). Mechanisms of antibiotic resistance. Front Microbiol, 6(34), 1-3. https://doi.org/10.3389/fmicb.2015.00034

Loureiro, R. J., Roque, F., Rodrigues, A. T., Herdeiro M. T. & Ramalheira, E. (2016). O uso de antibióticos e as resistências bacterianas: breves notas sobre a sua evolução. Revista Portuguesa de Saúde Pública, 34(1), 77-84. http://dx.doi.org/10.1016/j.rpsp.2015.11.003.

Matos, F. J. A. (1989). Introdução à fitoquímica experimental. Edições UFC.

Matos, F. J. A. (2009). Introdução à Fitoquímica Experimental (3nd ed.). Edições UFC.

Mendonça, A. T., Carvalho, A. R., Ferreira M. C., & Resende, M. C. Jr. (2016). A utilização dos extratos hidroalcoólico e alcoólico de eugenia uniflora L. como agente antibacteriano. Revista da Universidade Vale do Rio Verde, 14(1), 826-833. http://dx.doi.org/10.5892/ruvrd.v14i1.3019

Morais, D. A., Lobato, L. F. L., Viana, J. L., Zagmignan, A., Carvalho, G. P., Coutinho, G. G., Rezende, A. O., Alves, E. S., Maramaldo, C. E. C., Rocha, R. F., Lima, L. G. Neto., & Spuza, E. D. de. (2018). Análise da atividade antimicrobriana do extrato hidroalcoólico das folhas de Terminalia catappa contra Staphyloccocus aureus e Staphylococcus aureus resistente a meticilina - MRSA. Revista de Investigação Biomédica, 10(2), 107-113. https://doi.org/10.24863/rib.v10i2.243

Nugroho, R. A., Manurung, H., Saraswati, D., Ladyescha, D. & Nur, F. M. (2016). The Effects of Terminalia catappa L. Leaves Extract on the Water Quality Properties, Survival and Blood Profile of Ornamental fish (Betta sp) Cultured. Biosaintifika: Journal of Biology & Biology Education, 8(2), 240-247. https://doi.org/10.15294/biosaintifika.v8i2.6519

Poongulali, S., & Sundararaman, M. (2016). Antimycobacterial, anticandidal and antioxidant properties of Terminalia catappa and analysis of their bioactive chemicals. International Journal of Pharmacy and Biological Sciences, 6(2), 69-83. Recuperado de https://ijpbs.com/ijpbsadmin/upload/ijpbs_578a04d10329e.pdf

Sahira Banu, K. & Cathrine, L. (2015). General techniques involved in phytochemical analysis. International Journal of Advanced Research in Chemical Science, 2(4), 26-32. Recuperado de https://www.arcjournals.org/pdfs/ijarcs/v2-i4/5.pdf

Salares, E. F. O., & Balala, L. M. (2018). Phytochemical Screening and Antimicrobial Activity of Terminalia catappa L. Leaf Extract Against Potential Pathogens of Animals. Journal of Science, Engineering and Technology, 6, 15-25. Recuperado de https://www.ijterm.org/index.php/jset/article/view/24/20

Santos, O. V. dos., Lorenzo, N. D., & Lannes, S. C. S. (2016). Chemical, morphological, and thermogravimetric of Terminalia catappa Linn. Food Science and Technology, 36(1), 151-158. https://doi.org/10.1590/1678-457X.0090

Silva, M. O., & Aquino, S. (2018). Resistência aos antimicrobianos: uma revisão dos desafios na busca por novas alternativas de tratamento. Revista de Epidemiologia e Controle de Infecção, 8(4), 472-482. http://dx.doi.org/10.17058/reci.v8i4.11580

Souza, M. T. de., Silva, M. D. da., & Carvalho, R. de. (2010). Revisão integrativa: o que é e como fazer. Einstein (São Paulo), 8(1), 102-106. http://dx.doi.org/10.1590/s1679-45082010rw1134

Terças, A.G., Monteiro, A. S., Moffa, E. B., Santos, J. R. A. dos., Souza, E. M. de., Pinto, A. R. B., Costa, P. C. S., Borges, A. C. R., Torres, L. M. B., Barros, A. K. D., Filho., Fernandes, E. S., & Monteiro, C. A. (2017). Phytochemical Characterization of Terminalia catappa Linn. Extracts and Their antifungal Activities against Candida spp. Frontiers in Microbiology, 8(2), 1-13. https://doi.org/10.3389/fmicb.2017.00595

Published

06/12/2020

How to Cite

SILVA, D. C.; SOUSA, W. P. E. de; COSTA, D. de A. F. Phytochemical components and evidence of the antibacterial efficacy of Terminalia catappa leaf extracts against Staphylococcus aureus strains. Research, Society and Development, [S. l.], v. 9, n. 11, p. e89691110465, 2020. DOI: 10.33448/rsd-v9i11.10465. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/10465. Acesso em: 19 apr. 2024.

Issue

Section

Review Article