Oral transmission of Chagas disease: A literature review
DOI:
https://doi.org/10.33448/rsd-v10i2.12636Keywords:
Chagas disease; Trypanosoma cruzi Infection; Euterpe; Saccharum.Abstract
Chagas disease, known as American trypanosomiasis, is caused by the protozoan T. cruzi and endemic to Latin America, in which it represents one of the main socioeconomic problems in the region. Transmission routes can be vector, orally, by blood transfusion, organ transplantation, congenital transmission or laboratory accidents. Oral transmission stands out for being one of the main causes of acute Chagas disease (ACD) in some regions. Thus, the work aims to describe the main epidemiological outbreaks of infection with T. cruzi by oral contamination based on the literature and to identify the main sources, places and preventive measures taken in the face of these outbreaks caused by oral contamination. The bibliographic review was carried out in the databases: Latin American and Caribbean Literature in Health Sciences (LILACS), Scientific Electronic Library Online portal (SCIELO) and PubMed. At the end of the selection, 13 articles were used for the development of the study. The studies showed that the main foods associated with acute Chagas infection were sugarcane juice, açaí, açaí juice, contaminated water, palm heart juice and guava juice. The main localities affected were Brazil, Pará, Amapá and Amazonas, and other Latin American countries such as French Guiana and Venezuela. In addition, the studies pointed out sanitary control practices, the cooking process, the adoption of basic structural measures combined with not using artificial lighting as possible measures to reduce the risk of contamination in these areas. Finally, this work brings a survey that favors a better characterization of the importance of oral transmission of Chagas disease in the last 12 years in Latin America.
References
Barros, M. B. H., de Paula, C. M., Freitas, D. R. C., Das Neves P. A. Y., da Costa, V. V., Valente, S. A., Costa, E. G., & Sobel, J. (2009). Investigation of two outbreaks of suspected oral transmission of acute Chagas disease in the Amazon region, Pará State, Brazil, in 2007. Trop Doct. 39(4):231–2.
Bastos, C. J. C., Aras, R., Mota, G., Reis, F., Dias, J. P., de Jesus R. S., Freire, M. S., Araújo, E. G., Prazeres, J., & Grassi M. F. R. (2010). Clinical outcomes of thirteen patients with acute chagas disease acquired through oral transmission from two urban outbreaks in Northeastern Brazil. PLoS Negl Trop Dis. 4(6):16–7.
Benziger, C. P., Carmo, G. A. L., & Ribeiro, A. L. P. (2017). Chagas Cardiomyopathy: Clinical Presentation and Management in the Americas. Cardiol Clin. 35(1):31–47.
Blanchet, D., Brenière, S. F., Schijman, A. G., Bisio, M., Simon, S., Véron, V., Mayenced, C., Demar-Pierrea, M., Djossoue, F., & Aznar, C. (2014). First report of a family outbreak of Chagas disease in French Guiana and posttreatment follow-up. Infect Genet Evol. 28:245–50.
Carlier, Y., & Truyens, C. (2015) Congenital Chagas disease as an ecological model of interactions between Trypanosoma cruzi parasites, pregnant women, placenta and fetuses. Acta Trop. 103-115.
Chagas, C. (1922). Descoberta do Trypanosoma cruzi e verificação da tripanossomíase americana: retrospecto histórico. Memórias do Instituto Oswaldo Cruz. Vol. 15, p. 67–76.
Conners, E. E., Vinetz, J. M., Weeks, J. R., & Brouwer, K. C. (2016). A global systematic review of Chagas disease prevalence among migrants Graphical abstract HHS Public Access. Acta Trop. 156 (Mc 0507):68–78.
Conteh, L., Engels, T., & Molyneux, D. H. (2010). Socioeconomic aspects of neglected tropical diseases. Lancet. 375(9710):239–47.
Coura, J. R., & Vĩas, P. A. (2010). Chagas disease: A new worldwide challenge. Nature. Jun 24,465(7301):S6-7.
Coura, J. R. (2015). The main sceneries of chagas disease transmission. The vectors, blood and oral transmissions - A comprehensive review. Mem Inst Oswaldo Cruz. 110(3):277–82.
Dias, J. P., Bastos, C., Araújo, E., Mascarenhas, A. V., Netto, E. M., Grassi, F., Silva, M., Tatto, E., Mendonça, J., Araújo, R. F., Shikanai-Yasuda, M. A., & Aras, R. (2008). Acute Chagas disease outbreak associated with oral transmission. Rev Soc Bras Med Trop. 41(3):296–300.
Esper, H. R., de Freitas, V. L. T., Assy, J. G. P. L., Shimoda, E. Y., Berreta, O. C. P., Lopes, M. H., & França F. O. S. (2019). Fatal evolution of acute chagas disease in a child from northern Brazil: Factors that determine poor prognosis. Rev Inst Med Trop Sao Paulo.61:5–9.
Ferreira, R. T. B., Cabral, M. L., Martins, R. S., Araujo, P. F., Silva, S. A., Britto, C. Branquinho, M. R., Cardarelli-Leite, P., & Moreira, O. C. (2018). Detection and genotyping of Trypanosoma cruzi from açai products commercialized in Rio de Janeiro and Pará, Brazil. Parasites and Vectors. 11(1):1–11.
Groom, Z. C., Protopapas, A. D., & Zochios, V. (2017). Tropical diseases of the myocardium: A review. Int J Gen Med.10:101–11.
Lee, B. Y., Bacon, K. M., Bottazzi, M. E., & Hotez, P. J. (2013). Global economic burden of Chagas disease: A computational simulation model. Lancet Infect Dis.13(4):342–8.
Lidani, K. C. F., Bavia, L., Ambrosio, A. R., & de Messias-Reason, I. J. (2017). The complement system: A prey of Trypanosoma cruzi. Front Microbiol. 8(APR):1–14.
Marin-Neto, J. A., & Rassi, A. (2010). Update on Chagas Heart Disease on the First Centennial of Its Discovery. Rev Española Cardiol (English Ed. 62(11):1211–6.
Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., & Shekelle, P. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. January:1–9.
Nóbrega, A. A., Garcia, M. H., Tatto, E., Obara, M. T., Costa, E., Sobel, J., & Araujo W. N. (2009). Oral transmission of chagas disease by consumption of Açaí palm fruit, Brazil. Emerg Infect Dis. Apr, 15(4): 653–655.
Noya, B. A., Díaz‐Bello, Z., Colmenares, C., Ruiz‐Guevara, R., Mauriello, L., Zavala‐Jaspe, R., Suarez, J. A., Abate, T., Naranjo, L., Paiva, M., Rivas, L., Castro, J., Márques, J., Mendoza, I., Acquatella, H., Torres, J., & Noya, O. (2010). Large Urban Outbreak of Orally Acquired Acute Chagas Disease at a School in Caracas, Venezuela. J Infect Dis. 201(9):1308–15.
Noya, B. A., Pérez-Chacón G, Díaz-Bello, Z., Dickson, S., Muñoz-Calderón, A., Hernández, C., Pérez, Y., Mauriello, L., & Moronta, E. (2017). Description of an oral chagas disease outbreak in Venezuela, including a vertically transmitted case. Mem Inst Oswaldo Cruz. 112(8):569–71.
Parente, R. C. M., Oliveira, M. A. P., & De Celeste, R. K. (2012). Relatos e Série de Casos na Era da Medicina Baseada em Evidência. Brazilian J os Videoendoscopic Surg.3:67–70.
Sangenis, L. H. C., Nielebock, M. A. P., da Silva, S. C., da Silva M. C. C., & Bento, G. M. R. (2016). Transmissão da doença de Chagas por consumo de carne de caça: Revisão sistemática. Rev Bras Epidemiol.19(4):803–11.
Pérez-Molina, J. A., & Molina, I. (2017). Chagas disease. Lancet. 391(10115):82–94.
Sánchez, L. V., & Ramírez, J. D. (2013). Congenital and oral transmission of American trypanosomiasis: An overview of physiopathogenic aspects. Parasitology. 140(2):147–59.
Toso, M. A., Vial, U. F., & Galanti, N. (2011). Transmisión de la enfermedad de Chagas por vía oral. Rev Med Chil. 139: 258-266
Santana, R. A. G., Guerra, M. G. V. B., Sousa, D. R., Couceiro, K., Ortiz, J. V., Oliveira, M., Ferreira, L.S., Souza, K. R., Tavares, I. C., Morais, R. F., Silva, G. A. V., Melo, G. C., Vergel, G. M., Albuquerque, B. C., Arcanjo, A. R. L., Monteiro, W. M., Ferreira, J. B. B., Lacerda, M. V. G., Silveira, H., & Guerra, J. A. O. (2019). Oral transmission of Trypanosoma cruzi, Brazilian Amazon. Emerg Infect Dis. 25(1): 132–135.
Shikanai-Yasuda, M. A., & Carvalho, N. B. (2012). Oral transmission of chagas disease. Clin Infect Dis. Mar,54(6):845-52. 10.1093/cid/cir956.
Simões, M. V., Romano, M. M. D., Schmidt, A., Martins, K. S. M., & Marin-Neto, J. A. (2018). Cardiomiopatia da Doença de Chagas. Int J Cardiovasc Sci .31(2):173–89.
Souza, W., Carvalho, T. M. U., & Barrias, E. S. (2010). Review on Trypanosoma cruzi : Host Cell Interaction. Int J Cell Biol. 2010:1–18.
Souza-Lima, R. C., Barbosa, M. G. V., Coura, J. R., Arcanjo, A. R. L., Nascimento, A. S., Ferreira, J. M. B. B., Magalhães, L. K., Albuquerque, B. C., Araújo, G. A. N., & Guerra, J. A. O. (2013). Outbreak of acute Chagas disease associated with oral transmission in the Rio Negro region, Brazilian Amazon. Rev Soc Bras Med Trop.46(4):510–4.
Tanowitz, H. B., Machado, F. S., Jelicks, L. A., Shirani, J., Carvalho, A. C., Spray, D. C., Factor, S. M., Kirchhoff, V. L., & Weiss, L. M. (2009). Perspectives on Trypanosoma cruzi-Induced Heart Disease (Chagas Disease). Prog Cardiovasc Dis. 51(6):524–39.
Valente, S. A. S., da Costa, V. V., das Neves, P. A. Y., de Jesus, B. C. M., dos Santos, M. P., Miranda, C. O. S., Cuervo, P., & Fernandes, O. (2009). Analysis of an acute Chagas disease outbreak in the Brazilian Amazon: human cases, triatomines, reservoir mammals and parasites. Trans R Soc Trop Med Hyg. 103(3):291–7.
Vargas, A., Malta, J. M. A. S., da Costa, V. M., Cláudio, L. D. G., Alves, R. V., Cordeiro, G. S., Aguir L. M. A., & Percio, J. (2018). Investigação de surto de doença de Chagas aguda na região extra-amazônica, Rio Grande do Norte, Brasil, 2016. Cad Saude Publica. 34(1):e00006517.
World Health Organisation. (2020). Chagas disease (also known as American trypanosomiasis). Chagas Dis Fact Sheets [Internet]. https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)
Yoshida, N. (2008). Trypanosoma cruzi infection by oral route. How the interplay between parasite and host components modulates infectivity. Parasitology International Jun,57(2):105-9.
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Copyright (c) 2021 Luciano Vasconcellos Pacheco; Leonora Souza Santana; Breno Cardim Barreto; Emanuelle de Souza Santos; Cássio Santana Meira
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