Socio-epidemiological aspects and factors associated with tuberculosis / HIV co-infection - 10-year time series in Southeast Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v10i3.13062

Keywords:

Coinfection;; HIV Infections; Tuberculosis.

Abstract

To investigate the epidemiological behavior, sociodemographic aspects and factors related to the health-disease process of tuberculosis / HIV coinfection in the 4 states of Southeast Brazil, in a 10-year time series. This is a retrospective descriptive study with a quantitative approach of confirmed / reported cases of coinfection in southeastern Brazil. For data collection, the Disease Information System was consulted from 2007 to 2017, using TabWin as a tool for analysis of the variables of interest and the information obtained was tabulated with the help of EpiInfo 7.2 and Bioestat 5.3 softwares. A total of 317.188 records were analyzed, of which 45.552 cases of tuberculosis /HIV coinfection in southeastern Brazil. It was noted that 71.39% of individuals with both conditions

(34.68%) and aged between 30 to 39 years (34.62%) and only 1.78% had completed higher education. Regarding the clinical manifestation,the pulmonary form was more frequent(66.06%) and that a large proportion of the co-infected patients were socially vulnerable due to illicit drug use (14.49%), alcoholism (14.51%) and smoking (6.95%), resulting in treatment abandonment (17.16%) and deaths from other conditions (16.06%). The epidemiological behavior of tuberculosis / HIV coinfection increased considerably over the 10-year period due to the lack of adherence to tuberculosis therapy, which can negatively influence the HIV serological result, leading to high morbidity and mortality due to these health problems.

Author Biographies

Clea Adas Saliba Garbin , Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatuba.

Professora Titular do Programa de Pós-graduação em Saúde Coletiva em Odontologia , Departamento de Odontologia Preventiva e Restauradora.

Julia Arruda Batista, Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatuba.

PhD student of the Graduate Program in Public Health Dentistry, Department of Preventive Dentistry and Restorative.

Bruno Wakayama, Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatuba.

Master and Doctor in Collective Health in Dentistry.

Artênio José Saliba Garbin, Centro Universitário Católico Salesiano Auxilium (UniSalesiano).

Graduating in Medicine.

Orlando Adas Saliba Junior , Centro Universitário Católico Salesiano Auxilium (UniSalesiano)

Professor Doutor of the Medicine course.

Artênio Jose Isper Garbin , Universidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araçatuba.

Associate Professor of the Post-graduation Program in Collective Health in Odontology, Department of Preventive and Restorative Dentistry.

References

Amorim, L. T., & Schlemper Junior, B. R. (2019). HIV/AIDS in small cities in Midwest Santa Catarina, south of Brazil: Clinical and epidemiological aspects, opportunistic infections. Revista da Sociedade Brasileira de Medicina Tropical, 52, e20180430.

Bruchfeld, J., Correia-Neves, M., & Källenius, G. (2015). Tuberculosis and HIV coinfection. Cold Spring Harbor perspectives in medicine, 5(7), a017871.

Brunello, M. E. F., Chiaravalotti, N. F., Arcência, R. A., Andrade, R. L. P., Magnabosco, G. T., & Villa, T. C (2011) Áreas de vulnerabilidade para co-infecção HIV-aids/TUBERCULOSE em Ribeirão Preto, SP. Revista de Saúde Pública, 45, 556-563.

Cardoso, L. C., Melquiades, R., Magalhães, J. A., Carvalho, S. S., da Rosa, G., Merlini, L. S., & Julião, V. A. P. (2018). Aspectos epidemiológicos dos pacientes notificados com tuberculose na microrregião de Umuarama–noroeste paranaense de 2009 a 2014. Arquivos de Ciências da Saúde da UNIPAR, 22(3), 157-163.

Cui, Z., Lin, M., Nie, S., & Lan, R. (2017). Risk factors associated with Tuberculosis (TB) among people living with HIV/AIDS: A pair-matched case-control study in Guangxi, China. PLoS One, 12(3), e0173976.

Falana, A., Akpojiyovwi, V., Sey, E., Akpaffiong, A., Agumbah, O., Chienye, S., & Salihu, H. M. (2018). Hospital length of stay and cost burden of HIV, tuberculosis, and HIV-tuberculosis coinfection among pregnant women in the United States. American journal of infection control, 46(5), 564-570.

Frasca, K., & Cohn, J. (2014). Integration of HIV and tuberculosis in the community. Journal of the International Association of Providers of AIDS Care (JIAPAC), 13(6), 534-538.

Gesesew, H., Tsehaineh, B., Massa, D., Tesfay, A., Kahsay, H., & Mwanri, L. (2016). The prevalence and associated factors for delayed presentation for HIV care among tuberculosis/HIV co-infected patients in Southwest Ethiopia: a retrospective observational cohort. Infectious diseases of poverty, 5(1), 1-10.

Gopalan, N., Chandrasekaran, P., Swaminathan, S., & Tripathy, S. (2016). Current trends and intricacies in the management of HIV-associated pulmonary tuberculosis. AIDS research and therapy, 13(1), 1-19.

Kwan, C. K., & Ernst, J. D. (2011). HIV and tuberculosis: a deadly human syndemic. Clinical microbiology reviews, 24(2), 351-376.

Liberato, I. R. D. O., Albuquerque, M. D. F. P., Campelo, A. R. L., & Melo, H. R. L. D. (2004). Características da tuberculose pulmonar em pacientes com sorologia positiva e negativa para o HIV em uma região do Nordeste do Brasil. Revista da Sociedade Brasileira de Medicina Tropical, 37(1), 46-50.

Martinson, N. A., Hoffmann, C. J., & Chaisson, R. E. (2011). Epidemiology of tuberculosis and HIV: recent advances in understanding and responses. Proceedings of the American Thoracic Society, 8(3), 288-293.

Méndez‐Samperio, P. (2017). Diagnosis of tuberculosis in HIV co‐infected individuals: current status, challenges and opportunities for the future. Scandinavian journal of immunology, 86(2), 76-82.

Ministério da Saúde. Manual de Recomendações para o controle da Tuberculose no Brasil. Secretária de Vigilância em Saúde.

Oliveira, A. V. S. de, Alfonso, A. D., Miranda, R. S. de, & oliveira, T. R. S. de. (2020). Epidemiological profile of tuberculosis in the northeast of Brazil: temporary series from 2008 to 2018. Research, Society and Development, 9(2), e108922129.

Pawlowski, A., Jansson, M., Sköld, M., Rottenberg, M .E., & Källeniu, G. (2012) Tuberculosis and HIV co-infection. PLoS Pathogens, 8, e1002464.

Silva, D. R. (2018). Fatores de risco para tuberculose: diabetes, tabagismo, álcool e uso de outras drogas. Jornal Brasileiro de Pneumologia, 44, 145–152.

Silva, L. F. da, Carvalho, N. S. de, Souza, B. W. L. de, Castro, R. da C., Feitosa, A. P. A. R., & Martins, V. H. da S. (2020). Risk factors and complications of tuberculosis due to treatment abandonment. Research, Society and Development, 9(6), e109963501.

Sousa, G. O., Sales, B. N., Gomes, J. G. F., Silva, M. do A., & Oliveira, G. A. L. de. (2020). Tuberculosis epidemiology in northeastern Brazil, 2015 – 2019. Research, Society and Development, 9(8), e82985403.

Vachon, J., Gallant, V., & Siu, W. (2018). Can we eliminate tuberculosis?: Tuberculosis in Canada, 2016. Canada Communicable Disease Report, 44(3-4), 75-81.

Vendramini, S. H. F., Santos, N. S. G. M. D., Santos, M. D. L. S. G., Chiaravalloti Neto, F., Ponce, M. A. Z., Gazetta, C. E., & Ruffino Netto, A. (2010). Análise espacial da co-infecção tuberculose/HIV: relação com níveis socioeconômicos em município do sudeste do Brasil. Revista da Sociedade Brasileira de Medicina Tropical, 43, 536-541.

World Health Organization. (2017). Global turberculosis report 2017.

Zhu, Y., Wu, J., Feng, X., Chen, H., Lu, H., Chen, L., & Rui, C. (2017). Patient characteristics and perceived health status of individuals with HIV and tuberculosis coinfection in Guangxi, China. Medicine, 96(14), e6475.

Published

06/03/2021

How to Cite

GARBIN , C. A. S. .; BATISTA, J. A. .; WAKAYAMA, B.; GARBIN, A. J. S. .; SALIBA JUNIOR , O. A. .; GARBIN , A. J. I. . Socio-epidemiological aspects and factors associated with tuberculosis / HIV co-infection - 10-year time series in Southeast Brazil . Research, Society and Development, [S. l.], v. 10, n. 3, p. e6910313062, 2021. DOI: 10.33448/rsd-v10i3.13062. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13062. Acesso em: 12 apr. 2021.

Issue

Section

Health Sciences