Challenges in cancer management during SARS-CoV-2 pandemic: a systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i3.13251

Keywords:

COVID-19; SARS-CoV-2; Cancer; Oncology; Surgical oncology.

Abstract

The SARS-CoV-2 spread and the installation of a pandemic generated drastic changes in society's lifestyle, in health practices, and in the way we do and consume science. There are countless uncertainties regarding the virus and its health implications, especially for individuals from vulnerable groups, such as oncologic patients. The aim of this systematic review was to identify what has been the reality of oncology in the SARS-CoV-2 pandemic. A systematic review was carried out on the Pubmed® platform, based on the Prisma protocol, using the following keywords were searched: COVID-19 and Cancer. Among the 94 works selected, including systematic reviews, reviews, randomized trials, multicenter studies, meta-analysis, controlled clinical-trials, comparative studies and case reports, only 36 publications corresponded to the purpose of this study and were used. The results showed that, despite the large volume of studies, there is no consensus concerning gold standard measures. As individuals with cancer tend to evolve with more severe conditions when infected with SARS-CoV-2, oncology services have adopted protocols to guarantee adequate management and prevent the spread of the infection onto its facilities. The possible scarcity of resources during the SARS-CoV-2 pandemic brought the necessity to adapt adjust clinical conduct in oncology. Considering the severity and the possibility of a sudden progression of some types of cancer, the professionals must analyze all cases individually to determine the best approach.

References

Ackermann, M., Verleden, S. E., Kuehnel, M., Haverich, A., Welte, T., Laenger, F., Vanstapel, A., Werlein, C., Stark, H., Tzankov, A., Li, W. W., Li, V. W., Mentzer, S.J. & Jonigk, D. (2020). Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19. New England Journal of Medicine. DOI: 10.1056/NEJMoa2015432.

Al‐Shamsi, H. O., Alhazzani, W., Alhuraiji, A., Coomes, E. A., Chemaly, R. F., Almuhanna, M., Wolff, R. A., Ibrahim, N.K., Chua, M. L. K., Hotte, S. J., Meyers, B. M., Elfiki, T., Curigliano, G., Eng, C., Grothey, A. & Xie, C. (2020). A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID‐19) pandemic: an international collaborative group. The oncologist, 25(6), e936. DOI: 10.1634/theoncologist.2020-0213.

Albano, D., Bertagna, F., Bertoli, M., Bosio, G., Lucchini, S., Motta, F., Panarotto, M. B., Peli, A., Camoni, L., Bengel, F. M. & Giubbini, R. (2020). Incidental findings suggestive of COVID-19 in asymptomatic patients undergoing nuclear medicine procedures in a high-prevalence region. Journal of Nuclear Medicine, 61(5), 632-636. DOI: 10.2967/jnumed.120.246256.

Ardura, M., Hartley, D., Dandoy, C., Lehmann, L., Jaglowski, S., & Auletta, J. J. (2020). Addressing the impact of the Coronavirus Disease (COVID-19) pandemic on hematopoietic cell transplantation: Learning networks as means for sharing best practices. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.018.

Bachanova, V., Bishop, M. R., Dahi, P., Dholaria, B., Grupp, S. A., Hayes-Lattin, B., Janakiram, M., Maziarz, R. T., McGuirk, J. P., Nastoupil, L. J., Oluwole, O. O., Perales, M-A., Porter, D. L. & Riedell, P. A. (2020). CAR T Cell Therapy During the COVID-19 Pandemic. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.008.

Banna, G., Curioni-Fontecedro, A., Friedlaender, A., & Addeo, A. (2020). How we treat patients with lung cancer during the SARS-CoV-2 pandemic: primum non nocere. ESMO open, 4(Suppl 2), e000765. DOI:10.1136/ esmoopen-2020-000765.

Ciliberto, G., Mancini, R., & Paggi, M. G. (2020). Drug repurposing against COVID-19: focus on anticancer agents. Journal of Experimental & Clinical Cancer Research, 39, 1-9. DOI: 10.1186/s13046-020-01590-2.

Combs, S. E., Belka, C., Niyazi, M., Corradini, S., Pigorsch, S., Wilkens, J., Grosu, A. L., Guckenberger, M., Ganswindt, U. & Bernhardt, D. (2020). First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments. Radiation Oncology, 15, 1-12. DOI: 10.1186/s13014-020-01527-1.

Cucinotta, D., & Vanelli, M. (2020). WHO declares COVID-19 a pandemic. Acta bio-medica: Atenei Parmensis, 91(1), 157-160. DOI: 10.23750/abm.v91i1.9397.

Dariya, B., & Nagaraju, G. P. (2020). Understanding novel COVID-19: Its impact on organ failure and risk assessment for diabetic and cancer patients. Cytokine & Growth Factor Reviews. DOI: 10.1016/j.cytogfr.2020.05.001.

de la Viña, J. I., & Mayol, J., & Ortega, A. L., & Navarrete, B. A. (2020). Lung cancer patients on the waiting list in the midst of the COVID-19 crisis: what do we do now? Archivos de bronconeumologia. DOI: 10.1016/j.arbr.2020.05.003.

Deo, S., Kumar, S., Kumar, N., Saikia, J., Bhoriwal, S., Bhatnagar, S., & Sharma, A. (2020). Guiding Principles for Cancer Surgery during the COVID-19 Pandemic. Indian Journal of Surgical Oncology, 1. DOI: 10.1007/s13193-020-01082-x.

SILVA FILHO, P. S. da P.; COSTA, R. E. A. R. da; SANTOS, M. B. L. dos; LIMA, S. P. N.; SILVA, L. de A. da; FREITAS, A. S.; SILVA, J. P. da; ARAÚJO, L. K. C. de; CUNHA, S. H.; ARAÚJO, F. W. C.; SILVA, A. P. A. da; ALVES, D. R. C. F.; MENDES, A. M.; LEÃO, C. de A.; KIRCHESCH, C. L.; MACEDO, J. L. (2020). Management of patients with cancer during the COVID-19 pandemic. Research, Society and Development, 9 (7), p. e628974609, 2020. DOI: 10.33448/rsd-v9i7.4609.

Gandhi, R. T., Lynch, J. B., & del Rio, C. (2020). Mild or moderate COVID-19. New England Journal of Medicine. DOI: 10.1056/NEJMcp2009249.

Glehen, O., Kepenekian, V., Bouché, O., Gladieff, L., & Honore, C. (2020). Treatment of primary and metastatic peritoneal tumors in the Covid-19 pandemic. Journal of Visceral Surgery. DOI: 10.1016/j.jviscsurg.2020.04.013.

Gosain, R., Abdou, Y., Singh, A., Rana, N., Puzanov, I., & Ernstoff, M. S. (2020). COVID-19 and cancer: a comprehensive review. Current Oncology Reports, 22(5). DOI: 10.1007/s11912-020-00934-7.

Guo, Y.-R., Cao, Q.-D., Hong, Z.-S., Tan, Y.-Y., Chen, S.-D., Jin, H.-J., Tan, K-S., Wang, D-Y. & Yan, Y. (2020). The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Medical Research, 7(1), 1-10. DOI: 10.1186/s40779-020-00240-0.

Huang, Z., Yan, J., Jin, T., Huang, X., Zeng, G., Adashek, M. L., Wang, X., Li, J., Zhou, D. & Wu, Z. (2020). The Challenges Of Urgent Radical Sigmoid Colorectal Cancer Resection In A COVID-19 Patient; A Case Report. International Journal of Surgery Case Reports. DOI: 10.1016/j.ijscr.2020.04.088.

Ierardi, A. M., Wood, B. J., Gaudino, C., Angileri, S. A., Jones, E. C., Hausegger, K., & Carrafiello, G. (2020). How to Handle a COVID-19 Patient in the Angiographic Suite. Cardiovascular and Interventional Radiology, 1-7. DOI: 10.1007/s00270-020-02476-8.

Jin, X.-H., Zheng, K. I., Pan, K.-H., Xie, Y.P., & Zheng, M.-H. (2020). COVID-19 in a patient with chronic lymphocytic leukaemia. The Lancet Haematology, 7(4), e351-e352. DOI: 10.1016/S2352-3026(20)30074-0.

Kimmig, R., Verheijen, R. H., & Rudnicki, M. (2020). Robot assisted surgery during the COVID-19 pandemic, especially for gynecological cancer: a statement of the Society of European Robotic Gynaecological Surgery (SERGS). Journal of Gynecologic Oncology, 31(3). DOI: 10.3802/jgo.2020.31.e59.

Ky, B., & Mann, D. L. (2020). COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities. JACC: Basic to Translational Science, 5(5), 501-517. DOI: 10.1016/j.jacbts.2020.04.003.

Ljungman, P., Mikulska, M., de la Camara, R., Basak, G. W., Chabannon, C., Corbacioglu, S., Duarte, R., Dolstra, H., Lankester, A. C., Mohty, M., Montoto, S., Murray, J., de Latour, R. P., Snowden, J. A., Yakoub-Agha, I., Verhoeven, B., Kröger, N. & Styczynski, J. (2020). The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy. Bone marrow transplantation, 1-6. DOI: 10.1038/s41409-020-0919-0.

Mahmoudjafari, Z., Alexander, M., Roddy, J., Shaw, R., Shigle, T. L., Timlin, C., & Culos, K. (2020). American Society for Transplantation and Cellular Therapy Pharmacy Special Interest Group Position Statement on Pharmacy Practice Management and Clinical Management for COVID-19 in Hematopoietic Cell Transplant and Cellular Therapy Patients in the United States. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.005.

Minotti, C., Tirelli, F., Barbieri, E., Giaquinto, C., & Donà, D. (2020). How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. Journal of Infection. DOI: 10.1016/j.jinf.2020.04.026.

Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P. & Stewart, L. A. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic reviews, 4(1), 1. DOI: 10.1186/2046-4053-4-1.

Moujaess, E., Kourie, H. R., & Ghosn, M. (2020). Cancer patients and research during COVID-19 pandemic: a systematic review of current evidence. Critical Reviews in Oncology/Hematology, 102972. DOI: 10.1016/j.critrevonc.2020.102972.

Nannan, Z., Jie, S., Lizhong, Z., & Shuanying, Y. (2020). Clinical Characteristics and Coping Strategies of Neoplasms with 2019 Novel Coronavirus Infection. Chinese Journal of Lung Cancer, 23(4). DOI: 10.3779/j.issn.1009-3419.2020.102.15.

Paul, S., Rausch, C. R., Jain, N., Kadia, T., Ravandi, F., DiNardo, C. D., Welch, M. A., Dabaja, B. S., Daver, N., Garcia-Manero, G., Wierda, W., Pemmaraju, N., Bravo, G. M., Thompson, P., Verstovsek, S., Konopleva, M., Kantarjian, H. & Jabbour, E. (2020). Treating Leukemia in the Time of COVID-19. Acta Haematologica, 1-13. DOI: 10.1159/000508199.

Pawar, T., Pokharkar, A., Gori, J., Pandey, D., Rohila, J., Dsouza, A., & Saklani, A. (2020). The Technique and Justification for Minimally Invasive Surgery in COVID-19 Pandemic: Laparoscopic Anterior Resection for Near Obstructed Rectal Carcinoma. Journal of Laparoendoscopic & Advanced Surgical Techniques, 30(5), 485-487. DOI: 10.1089/lap.2020.0241.

Pimentel, B. (2020). As disfunções olfativas e gustativas como apresentação clínica da COVID-19. Research, Society and Development, 9 (8), e64985072. DOI: http://dx.doi.org/10.33448/rsd-v9i8.5072.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da Pesquisa Científica. [e-book]. (1ª ed). Santa Maria: UAB/NTE/UFSM. Retrieved from: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa -Cientifica.pdf?sequence=1. Access in: 04 mar. 2021.

Puliatti, S., Eissa, A., Eissa, R., Amato, M., Mazzone, E., Dell’Oglio, P., Sighinolfi, M. C., Zoeir, A., Micali, S., Bianchi, G., Patel, V., Wiklund, P., Coelho, R. F., Bernhard, J-C., Dasgupta, P., Mottrie, A. & Rocco, B. (2020). COVID‐19 and urology: A comprehensive review of the literature. BJU international. DOI: 10.1111/bju.15071.

Shinde, R. S., Naik, M. D., Shinde, S. R., Bhandare, M. S., Chaudhari, V. A., Shrikhande, S. V., & Dcruz, A. K. (2020). To Do or Not to Do?—A Review of Cancer Surgery Triage Guidelines in COVID-19 Pandemic. Indian Journal of Surgical Oncology, 1. DOI: 10.1007/s13193-020-01086-7.

Spezzani, V., Piunno, A., & Iselin, H.-U. (2020). Benign COVID-19 in an immunocompromised cancer patient-the case of a married couple. Swiss Medical Weekly, 150(1516). DOI: 10.4414/smw.2020.20246.

Tchelebi, L. T., Haustermans, K., Scorsetti, M., Hosni, A., Huguet, F., Hawkins, M. A., Dawson, L. A. & Goodman, K. A. (2020). Recommendations on the use of radiation therapy in managing patients with gastrointestinal malignancies in the era of COVID-19. Radiotherapy and Oncology. DOI: 10.1016/j.radonc.2020.04.010.

Tian, S., Hu, W., Niu, L., Liu, H., Xu, H., & Xiao, S.-Y. (2020). Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer. Journal of Thoracic Oncology. DOI: 10.1016/j.jtho.2020.02.010.

van de Haar, J., Hoes, L. R., Coles, C. E., Seamon, K., Fröhling, S., Jäger, D., Valenza, F., de Braud, F., de Petris, L., Bergh, J., Ernberg, I., Besse, B., Barlesi, F., Garralda, E., Piris-Giménez, A., Baumann, M., Apolone, G., Soria, J. C., Tabernero, J., Caldas, C. & Voest, E. E. (2020). Caring for patients with cancer in the COVID-19 era. Nature Medicine, 26(5), 665-671. DOI: 10.1038/s41591-020-0874-8.

von Lilienfeld-Toal, M., Vehreschild, J. J., Cornely, O., Pagano, L., Compagno, F., & Hirsch, H. H. (2020). Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases. Leukemia, 1-8. DOI: 10.1038/s41375-020-0832-y.

Wei, W., Zheng, D., Lei, Y., Wu, S., Verma, V., Liu, Y., Wei, X., Bi, J., Hu, D. & Han, G. (2020). Radiotherapy workflow and protection procedures during the Coronavirus Disease 2019 (COVID-19) outbreak: Experience of the Hubei Cancer Hospital in Wuhan, China. Radiotherapy and Oncology. DOI: 10.1016/j.radonc.2020.03.029.

Weisel, K. C., Morgner-Miehlke, A., Petersen, C., Fiedler, W., Block, A., Schafhausen, P., Knobloch, J. K. & Bokemeyer, C. (2020). Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg. Oncology Research and Treatment, 43(6), 307-313. DOI: 10.1159/000508272.

Weller, M., & Preusser, M. (2020). How we treat patients with brain tumour during the COVID-19 pandemic. ESMO open, 4(Suppl 2), e000789. DOI: 10.1136/esmoopen-2020-000789.

World Health Organization (2020). Rolling updates on coronavirus disease (COVID-19). Retrieved from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen.

Ye, Z., Hong, Y., Wu, X., Hong, D., Zhang, Y., Dong, X., Rao, Y. & Lu, X. (2020). Management of a colon cancer patient infected with corona virus disease 2019. Journal of Zhejiang University (Medical Science), 49(1), 0-0. DOI: 10.3785/j.issn.1008-9292.2020.03.12.

Yeo, C., Kaushal, S., & Yeo, D. (2020). Enteric involvement of coronaviruses: is faecal–oral transmission of SARS-CoV-2 possible? The lancet Gastroenterology & hepatology, 5(4), 335-337. DOI: 10.1016/S2468-1253(20)30048-0.

Zhang, H., Xie, C., & Huang, Y. (2020c). Treatment and outcome of a patient with lung cancer infected with severe acute respiratory syndrome Coronavirus-2. Journal of Thoracic Oncology, 15(5), e63-e64. DOI: 10.1016/j.jtho.2020.02.025.

Zhang, L., Zhu, F., Xie, L., Wang, C., Wang, J., Chen, R., Jia, P., Guan, H. Q., Peng, L., Chen, Y., Peng, P., Zhang, P., Chu, Q., Shen, Q., Wang, Y., Xu, S.Y., Zhao, P. J., & Zhou, M. (2020a). Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Annals of Oncology. DOI: 10.1016/j.annonc.2020.03.296.

Zhang, X., Song, K., Tong, F., Fei, M., Fei, M., Guo, H., Lu, Z., Wang, J., & Zheng, C. (2020b). First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab. Blood advances, 4(7), 1307. DOI: 10.1182/bloodadvances.2020001907.

Downloads

Published

14/03/2021

How to Cite

OLIVEIRA, A. P. A. .; SCHAFRANEK , A. R. de M. .; CARVALHO , L. de O. B. .; VITRO , M. M. de .; FRAZÃO , R. M. .; NASCIMENTO , V. A. .; OLIVEIRA, P. F. de. Challenges in cancer management during SARS-CoV-2 pandemic: a systematic review . Research, Society and Development, [S. l.], v. 10, n. 3, p. e25910313251, 2021. DOI: 10.33448/rsd-v10i3.13251. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13251. Acesso em: 14 nov. 2024.

Issue

Vol. 10 No. 3

Section

Review Article

License

Copyright (c) 2021 Alan Paulo Amaral Oliveira; Alícia Rocha de Mesquita Schafranek ; Larissa de Oliveira Briganti Carvalho ; Mariana Martins de Vitro ; Renata Messias Frazão ; Victor Alves Nascimento ; Pollyanna Francielli de Oliveira

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.