Antioxidant potential of Pfaffia glomerata and Arrabidaea chica extracts combination
DOI:
https://doi.org/10.33448/rsd-v10i4.14150Keywords:
Brazilian ginseng; Pariri; Antioxidant activity; Synergism.Abstract
Several therapeutic benefits of medicinal plants are attributed to antioxidant properties, since antioxidant compounds play an important role in the prevention of various diseases and aging. Many products have synergistic action from combinations of plant extracts that contain natural antioxidants. The present study aimed to evaluate the synergistic effect of Pfaffia glomerata extract with Arrabidaea chica extract for antioxidant action. In the study the extract of the inflorescences of P. glomerata and the extract of the leaves of A. chica were used. The synergism between P. glomerata extract and A. chica extract was evaluated using the ratio between experimental and theoretical antioxidant activity, which was determined using the DPPH method and the potential total reactive antioxidant method (TRAP). The combination of P. glomerata extract and A. chica extract showed a synergistic effect, in which the antioxidant property of this combination was substantially superior to the sum of the individual antioxidant effects. This demonstrates that the combined extracts can be important for the development of products that have a high antioxidant potential.
References
Alves, J. M., & Souza, A. O. (2020). O perfil antioxidante no ritmo circadiano de Jambos malaccensis, Ocimum gratissimum e Astrocaryum aculeatum. Revista Ensino, Saúde e Biotecnologia da Amazônia, 2(1), 19-28.
Barbosa, W. L. R., Pinto, L. D. N., Quignard, E., Vieira, J. M. D. S., Silva Jr, J. O. C., & Albuquerque, S. (2008). Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities. Revista Brasileira de Farmacognosia, 18(4), 544-548.
Beddows, C. G., Jagait, C., & Kelly, M. J. (2001). Effect of ascorbyl palmitate on the preservation of α-tocopherol in sunflower oil, alone and with herbs and spices. Food Chemistry, 73(3), 255-261.
Brand-Williams, W., Cuvelier, M. E., & Berset, C. L. W. T. (1995). Use of a free radical method to evaluate antioxidant activity. LWT-Food science and Technology, 28(1), 25-30.
Cai, Y., Luo, Q., Sun, M., & Corke, H. (2004). Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life sciences, 74(17), 2157-2184.
Capasso, A., & Sorrentino, L. (2005). Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination. Phytomedicine, 12(1-2), 39-45.
Daniel, J. F. S., Alves, K. Z., Jacques, D. S, Souza, P. D. S., de Carvalho, M. G., Freire, R. B., Ferreira, D. T., & Freire, M. F. (2005). Free radical scavenging activity of Pfaffia glomerata (Spreng.) Pederson (Amaranthaceae). Indian journal of pharmacology, 37(3), 174.
de Azevedo, S. S., Mesquita, G. P., Mendes, Y. C., Costa, G. D. E., da Silva, L. C. N., & Zagmignan, A. (2020). Avaliação da atividade antioxidante de chás comercializados em feiras livres e de chás industrializados em São Luís-Maranhão, Brasil. Research, Society and Development, 9(8), e06985320-e06985320.
de Freitas, L. M. A., Gomes, B. C. R., Nascimento, C. F., Lage, I. L., Caricati, J. M. M. P., de Sena Silva, L. A., dos Santos, M.J.C., Silva, S.R.A., & de Souza Almeida, V. L. (2020). Antioxidantes como forma de prevenção contra a ação dos radicais livres no processo de envelhecimento cutâneo. ÚNICA Cadernos Acadêmicos, 3(1). 1-10
de Moraes, T. V., Ferreira, J. P. G., de Souza, M. R. A., & Moreira, R. F. A. (2020). Atividade antioxidante e conteúdo de compostos fenólicos do chá do caule da Pereskia aculeata Miller fresco e armazenado sob congelamento. Research, Society and Development, 9(5), e34953140-e34953140.
de Souza, D. A. A., da Luz Correa, A. P., da Silva, P. M. M., & da Conceição, L. R. V. (2020). Avaliação do potencial de misturas de antioxidantes naturais e sintético na estabilidade oxidativa de biodiesel. Brazilian Journal of Development, 6(10), 74562-74578.
Dias Filho, B. P., Nakamura, C. V., Cortez, D. A. G., Siraichi, J. T. G., Serra, L. Z. , Puhl, C. M. N., & Nakamura, T. U. (2009). Formulação farmacêutica à base da espécie vegetal Arrabidaea chica para fotoproteção e pigmentação. Brasil patent PI 0703095.
Dinan, L., & Lafont, R. (2006). Effects and applications of arthropod steroid hormones (ecdysteroids) in mammals. Journal of Endocrinology, 191(1), 1-8.
Felipe, D. F., Brambilla, L. Z., Porto, C., Pilau, E. J., & Cortez, D. A. (2014). Phytochemical analysis of Pfaffia glomerata inflorescences by LC-ESI-MS/MS. Molecules, 19(10), 15720-15734.
Franco, R. R., de Almeida Takata, L., Chagas, K., Justino, A. B., Saraiva, A. L., Goulart, L. R., Ávila, V. M. R., Otoni, W. C., Espindola, F. S., & da Silva, C. R. (2021). A 20-hydroxyecdysone-enriched fraction from Pfaffia glomerata (Spreng.) pedersen roots alleviates stress, anxiety, and depression in mice. Journal of Ethnopharmacology, 267, 113599.
Fuhrman, B., Volkova, N., Rosenblat, M., & Aviram, M. (2000). Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic. Antioxidants and Redox Signaling, 2(3), 491-506.
Gang, C.G., Cho, S.A., Kim, J.H., Jang, H.G., Cho, & J.C. (2012). The cosmetic composition for sunscreen for the antiaging controlling the nerve cell damage due to the ultraviolet ray. Korea patent KR 1155180.
Gaspar, L. R., Camargo Jr, F. B., Gianeti, M. D., & Campos, P. M. (2008). Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitamins. Food and chemical toxicology, 46(11), 3493-3500.
Ghiselli, A., Serafini, M., Natella, F., & Scaccini, C. (2000). Total antioxidant capacity as a tool to assess redox status: critical view and experimental data. Free Radical Biology and Medicine, 29(11), 1106-1114.
Henrique, A. D. S., & Lopes, G. C. (2017). Biodiversidade e a indústria de cosméticos: O uso dos flavonóides contra o envelhecimento cutâneo. Revista Uningá Review, 29(2), 58-63.
Jiménez-Estrada, M., Velázquez-Contreras, C., Garibay-Escobar, A., Sierras-Canchola, D., Lapizco-Vázquez, R., Ortiz-Sandoval, C., Burgos-Hernández, A., & Robles-Zepeda, R. E. (2013). In vitro antioxidant and antiproliferative activities of plants of the ethnopharmacopeia from northwest of Mexico. BMC complementary and alternative medicine, 13(1), 1-8.
Jorge, M. P., Madjarof, C., Ruiz, A. L. T. G., Fernandes, A. T., Rodrigues, R. A. F., de Oliveira Sousa, I. M., Foglio, M.A., & de Carvalho, J. E. (2008). Evaluation of wound healing properties of Arrabidaea chica Verlot extract. Journal of Ethnopharmacology, 118(3), 361-366.
Kaim, M., & Backes, L. T. H. (2019). Envelhecimento celular: teorias e mecanismos. Revista Saúde Integrada, 12(23), 178-189.
Kalim, M. D., Bhattacharyya, D., Banerjee, A., & Chattopadhyay, S. (2010). Oxidative DNA damage preventive activity and antioxidant potential of plants used in Unani system of medicine. BMC Complementary and alternative medicine, 10(1), 1-11.
Kirakosyan, A., Seymour, E. M., Noon, K. R., Llanes, D. E. U., Kaufman, P. B., Warber, S. L., & Bolling, S. F. (2010). Interactions of antioxidants isolated from tart cherry (Prunus cerasus) fruits. Food Chemistry, 122(1), 78-83.
Kusumawati I., & Indrayanto G. (2013). Natural antioxidants in cosmetics. Studies in Natural Products Chemistry, 40, 485-505.
Lafont, R., & Dinan, L. (2003). Practical uses for ecdysteroids in mammals including humans: and update. Journal of insect science, 3(1), 1-30.
Lee, C.G., Kim, J.Y., Jang, H.G., Min, D.J., & Cho, J.C. (2012). The cosmetic composition for the dynamic activation of a skin cell. Korea patent KR 1116447.
Lima, A. F., de Jesus Santana, E. C., & Moreira, J. A. R. (2018). Atuaça o da vinhoterapia no retardo do envelhecimento cuta neo: revisa o de literatura. Revista Científica da FHO v, 6(2), 1-18.
Liu, D., Shi, J., Ibarra, A. C., Kakuda, Y., & Xue, S. J. (2008). The scavenging capacity and synergistic effects of lycopene, vitamin E, vitamin C, and β-carotene mixtures on the DPPH free radical. LWT-Food Science and Technology, 41(7), 1344-1349.
Massarolo, K. C., de Souza, T. D., Collazzo, C. C., Furlong, E. B., & de Souza Soares, L. A. (2017). The impact of Rhizopus oryzae cultivation on rice bran: Gamma-oryzanol recovery and its antioxidant properties. Food chemistry, 228, 43-49.
Meybeck, A., Bonte, F., Redziniak, G. (1997). Use of an ecdysteroid for the preparation of cosmetic or dermatological compositions intended, in particular, for strengthening the water barrier function of the skin or for the preparation of a skin cell culture medium, as well as to the compositions. United States patent US5609873.
Nsimba, R. Y., Kikuzaki, H., & Konishi, Y. (2008). Ecdysteroids act as inhibitors of calf skin collagenase and oxidative stress. Journal of biochemical and molecular toxicology, 22(4), 240-250.
Oliveira, C. B. D., & Sakai, O. A. (2020). Clean Technologies for Obtaining Biocomposites of Brazilian Ginseng Pfaffia glomerata (Spreng.) Pedersen: A Review. European Journal of Medicinal Plants, 31(14), 18-31.
Pellegrini, N., Serafini, M., Colombi, B., Del Rio, D., Salvatore, S., Bianchi, M., & Brighenti, F. (2003). Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. The Journal of nutrition, 133(9), 2812-2819.
Peschel, W., Sánchez-Rabaneda, F., Diekmann, W., Plescher, A., Gartzía, I., Jiménez, D., Lamuela-Raventós R., Buxaderas S., & Codina, C. (2006). An industrial approach in the search of natural antioxidants from vegetable and fruit wastes. Food Chemistry, 97(1), 137-150.
Radi, R. (2018). Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine. Proceedings of the National Academy of Sciences, 115(23), 5839-5848.
Repetto, M., Reides, C., Carretero, M. L. G., Costa, M., Griemberg, G., & Llesuy, S. (1996). Oxidative stress in blood of HIV infected patients. Clinica Chimica Acta, 255(2), 107-117.
Ribeiro, A. F. C., Telles, T. C., Ferraz, V. P., Souza-Fagundes, E. M., Cassali, G. D., Carvalho, A. T., & Melo, M. M. (2012). Effect of Arrabidaea chica extracts on the Ehrlich solid tumor development. Brazilian Journal of Pharmacognosy 22(2), 364-373.
Scherer, R., & Godoy, H. T. (2009). Antioxidant activity index (AAI) by the 2, 2-diphenyl-1-picrylhydrazyl method. Food chemistry, 112(3), 654-658.
Scholey, A. B., & Kennedy, D. O. (2002). Acute, dose‐dependent cognitive effects of Ginkgo biloba, Panax ginseng and their combination in healthy young volunteers: Differential interactions with cognitive demand. Human Psychopharmacology: Clinical and Experimental, 17(1), 35-44.
Serra, L.Z., Felipe, D.F., & Cortez, D.A.G. (2012). Quantification of β-ecdysone in differents parts of Pfaffia glomerata by HPLC. Brazilian Journal of Pharmacognosy, 22(6), 1349-1354.
Silva, E. M., Souza, J. N. S., Rogez, H., Rees, J. F., & Larondelle, Y. (2007). Antioxidant activities and polyphenolic contents of fifteen selected plant species from the Amazonian region. Food chemistry, 101(3), 1012-1018.
Silva, M. I., Ribas-Filho, O., Malafaia, O., Nassif, P. A. N., Ribas, M. M., Varaschim, M., & Czeczko, L. E. (2010). A utilização da Pfaffia glomerata no processo de cicatrização de feridas da pele. Arquivos brasileiros de cirurgia digestiva, 23(4), 28-233.
Siraichi, J. T. G., Felipe, D. F., Brambilla, L. Z. S., Gatto, M. J., Terra, V. A., Cecchini, A. L., & Cortez, D. A. G. (2013). Antioxidant capacity of the leaf extract obtained from Arrabidaea chica cultivated in Southern Brazil. PLoS One, 8(8), 1-9.
Souza, L. D. Z. D. S., Fonseca, S. R. A. V. D., Ferrari, A., & Felipe, D. F. (2021). β-ecdysone content and antioxidant capacity in different organs of Brazilian ginseng. Ciência Rural, 51(5), 1-9.
Tarahovsky, Y. S., Muzafarov, E. N., & Kim, Y. A. (2008). Rafts making and rafts braking: how plant flavonoids may control membrane heterogeneity. Molecular and cellular biochemistry, 314(1), 65-71.
Vellosa, J. C. R., Biavatti, M., Françóia, P. C. O., de Mello, B. J., de Almeida, A. C., & Bueno, G. E. (2021). Estresse oxidativo: uma introdução ao estado da arte. Brazilian Journal of Development, 7(1), 10152-10168.
Wagner, H. (2006). Multitarget therapy–the future of treatment for more than just functional dyspepsia. Phytomedicine, 13, 122-129.
Wheatley, D. (2001). Stress‐induced insomnia treated with kava and valerian: singly and in combination. Human Psychopharmacology: Clinical and Experimental, 16(4), 353-356.
Williamson, E. M. (2001). Synergy and other interactions in phytomedicines. Phytomedicine, 8(5), 401-409.
Wróblewska, K. B., Baby, A. R., Guaratini, M. T. G., & Moreno, P. R. H. (2019). In vitro antioxidant and photoprotective activity of five native Brazilian bamboo species. Industrial Crops and Products, 130, 208-215.
Zhang, L., Ravipati, A. S., Koyyalamudi, S. R., Jeong, S. C., Reddy, N., Smith, P. T., Bartlett, J., Shanmugam, K., Münch, D.G., & Wu, M. J. (2011). Antioxidant and anti-inflammatory activities of selected medicinal plants containing phenolic and flavonoid compounds. Journal of agricultural and food chemistry, 59(23), 12361-12367.
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