Bioactivity of Ti6Al4V alloy with bioglass and corrosion protection by silane coating




Biocompatibility; Bioglass; Corrosion; Silane Film; Ti6Al4V.


The Ti6Al4V alloy is usually employed as a biomaterial, however, when in use, exhibits a few drawbacks such as corrosion, caused by the release of aluminum and vanadium ions besides the bioinert behavior. Bioactive coatings offer a barrier effect and bioactivity, promoting biocompatibility and osseointegration processes. The present work aims to study the biocompatibility behavior of a bioglass-containing silane film deposited on a titanium alloy (Ti6Al4V) substrate. The effect of the surface roughness of the metallic substrate was also evaluated. Film/substrate systems were characterized as their morphological, chemical, physical, electrochemical behavior, and cell cytotoxicity and cell viability. The main results pointed out that silane films augment corrosion resistance of titanium alloy substrates. The biological results indicated a growth of osteoblast cells (MG-63), for all the test conditions. The bioglass film deposited on the ground substrate exhibits the highest cell density.

Author Biographies

Patricia Marcolin, Universidade de Caxias do Sul

Universidade de Caxias do Sul

Caroline Olivieri da Silva Frozza, Universidade de Caxias do Sul

Universidade de Caxias do Sul

João Antonio Pêgas Henriques, Universidade de Caxias do Sul

Universidade de Caxias do Sul

Sandra Raquel Kunst, FEEVALE University

FEEVALE University

Murilo Camuri Crovace, Federal University of São Carlos

Federal University of São Carlos

Mariana Roesch Ely , Universidade de Caxias do Sul

Universidade de Caxias do Sul

Lucia Vieira, University of Paraiba Valley

University of Paraiba Valley

María Cristina Moré Farias, Universidade de Caxias do Sul

Universidade de Caxias do Sul

Rosmary Nichele Brandalise, Universidade de Caxias do Sul

Universidade de Caxias do Su


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How to Cite

MARCOLIN, P.; FROZZA, C. O. da S. .; HENRIQUES, J. A. P. .; KUNST, S. R. .; CROVACE, M. C. .; ELY , M. R. .; VIEIRA, L. .; FARIAS, M. C. M. .; BRANDALISE, R. N. . Bioactivity of Ti6Al4V alloy with bioglass and corrosion protection by silane coating. Research, Society and Development, [S. l.], v. 10, n. 6, p. e23310615308, 2021. DOI: 10.33448/rsd-v10i6.15308. Disponível em: Acesso em: 27 jan. 2023.