Properties of platelet-rich fibrin (PRF) applied to oral surgery - Choukroun protocol
DOI:
https://doi.org/10.33448/rsd-v10i5.15338Keywords:
Blood platelets; Fibrin; Platelet-rich fibrin; Bone regeneration; Oral surgery.Abstract
The development of bioactive surgical additives to regulate inflammation and increase the speed of the healing process is one of the great challenges of clinical research. Because in surgical procedures they often used techniques that, in most cases, were very invasive and caused discomfort to the patient. In this sense, platelet-rich fibrin (PRF) appears as a natural, viable and quite satisfactory alternative with favorable results and presenting low risks. The PRF (Fibrin Rich in Platelets) was developed by Choukroun for use in oral and maxillofacial surgery, and has several areas of application within dentistry, which can mention the bone increase in implantology, maxillary sinus lifting, alveolar transplantation, aesthetic periodontal surgery, among others. The following review is a literature review study on the properties of platelet-rich fibrin (PRF) applied to oral surgery-choukroun protocol, based on 24 selected articles from 40 researched articles focusing on its preparation, advantages and disadvantages of using it in clinical applications, especially its use in oral surgery.
References
Ali, S., Bakry, S. A., & Abd-Elhakam, H. (2015). Platelet-rich fibrin in maxillary sinus augmentation: a systematic review. J Oral Implantol, 41 (6): 746-753.
Aroca, S., Keglevich, T., Barbieri, B., Gera, I., & Etienne, D. (2009) Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study. J Periodontol, 80 (2): 244-252.
Bajaj, P., Pradeep, A. R., Agarwal, E., et al. (2013). Comparative evaluation of autologous platelet-rich fibrin and platelet-rich plasma in the treatment of mandibular degree II furcation defects: a randomized controlled clinical trial. J Periodont Res, 48 (5): 573-581.
Bolukbasi, N., Ersanli, S., Keklikoglu, N., Basegmez, C., & Ozdemir, T. (2015) Sinus Augmentation With Platelet-Rich Fibrin in Combination With Bovine Bone Graft Versus Bovine Bone Graft in Combination With Collagen Membrane. J Oral Implantol, 41 (5): 586-595.
Choukroun, J., Diss, A., Simonpieri, A., Girard, M. O., Schoeffler, C., Dohan, S. L., Dohan, A. J., Mouhyi, J., & Dohan, D. M. (2006). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101: e56-60.
Corso M. D., Toffler M., David M., & Ehrenfest D. (2010). Use of an autologous leukocyte and platelet-rich fibrin (L-PRF) membrane in post-avulsion sites: An overview of Choukroun's PRF. O jornal de implantes e odontologia clínica avançada, 1 (9): 27-35.
Desarda, H. M., Gurav, A. N., Gaikwad, S. P., & Inamdar, S. P. (2013). Platelet rich fibrin: a new hope for regeneration in aggressive periodontitis patients: report of two cases. Indian J Dent Res., 24: 627-630.
Gil, A. T. C. (2002). Como elaborar projetos de pesquisa. Atlas.
Gupta, V., Bains, B. K., Singh, G. P., Mathur, A., & Bains, R. (2011). Regenerative Potential of Platelet Rich Fibrin In Dentistry: Literature Review. Asian J Oral Health Allied Sci, 1: 22-28.
Hauser, F., Gaydarov, N., Badoud, I., et al. (2013). Clinical and histological evaluation of postextraction platelet-rich fibrin socket filling: a prospective randomized controlled study. Implant Dent., 22 (3): 295-303.
Inchigolo, F., Tatullo, M., Marrelli, M., et al. (2010). Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations. Eur Rev Med Pharmacol Sei., 14 (12): 1075-1084.
Kawase, T., Kamiya, M., Kobayashi, M., Tanaka, T., Okuda, K., Wolff, L. F., & Yoshie, H. (2015). The heat-compression technique for the conversion of platelet-rich fibrin preparation to a barrier membrane with a reduced rate of biodegradation. J Biomed Mater Res B Appl Biomater, 103: 825-31.
Kerhwald, R., et al. (2021). Uso de fibrina rica em plaqueta em enxerto ósseo e implantes dentários, Research, Society and Development, 10 (1): e56510112210. Doi: http://dx.doi.org/10.33448/rsd-v10i1.12210
Kiran, N. K., Mukunda, K. S., & Tilak Raj, T. N. (2011). Platelet concentrates: A promising innovation in dentistry. J Dent Sci Res, 2: 50-61.
Lins, V. F., Brandão, D. G., & Rocha, S. M. W. (2021). A utilização da fibrina rica em plaquetas em procedimentos estéticos orofaciais: uma revisão integrativa. Research, Society and Development, 10 (3): e27910313477. Doi: http://dx.doi.org/10.33448/rsd-v10i3.13477
Magremanne, M., Baeyens, W., Awada, S., & Vervaet, C. (2009). Solitary bone cyst of the mandible and platelet rich fibrin (PRF). Rev Stomatol Chir Maxillofac., 110 (2): 105-108.
Peck, M. T., Marnewick, J., & Stephen, L. (2011) Alveolar Ridge Preservation Using Leukocyte and Platelet-Rich Fibrin: A Report of a Case. Case Rep Dent., 345048.
Saluja, H., Dehane, V. & Mahindra, U. (2011). PlateletRich fibrin: Platelet-Rich fibrin: A second generation platelet concentrate and a new friend of oral and maxillofacial surgeons. Ann Maxillofac Surg., 1: 53-57.
Simonpieri, A, Del Corso M, Vervelle A, Jimbo R, Inchingolo F, Sammartino G., & Dohan Ehrenfest D. M. (2012). Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 2: Bone graft, implant and reconstructive surgery. Curr Pharm Biotechnol, 13: 1231-1256.
Tatullo M, Marrelli M, Cassetta M, Pacifici A, Stefanelli LV, Scacco S, Dipalma G, Pacifici L & Inchingolo F. (2012). Platelet Rich Fibrin (P.R.F.) in Reconstructive Surgery of Atrophied Maxillary Bones: Clinical and Histological Evaluations. Int J Med Sci., 9: 872-880.
Tchemra, F. G. C., et al. (2021). Efetividade do uso da Fibrina Rica em Plaquetas (PRF) no levantamento de seio maxilar: relato de caso. Research, Society and Development, 10 (1): e29210111492. Doi: http://dx.doi.org/10.33448/rsd-v10i1.11492
Thorat, M. K., Pradeep, A. R., & Pallavi, B. (2011). Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial. J Clin Periodontol., 38: 925-932.
Toeroek, R., & Dohan, E. D. M. (2013). The concept of Screw-Guided Bone Regeneration (S-GBR). Part 3: fast screw-guided bone regeneration (FS-GBR) in the severely resorbed preimplant posterior mandible using allograft and leukocyte- and platelet-rich fibrin (L-PRF): a 4-year follow-up. POSEIDO, 1 (2): 93-100.
Toffler M, Toscano N & Holtzclaw D. (2010). Osteotome-Mediated Sinus Floor Elevation Using Only Platelet-Rich Fibrin: An Early Report on 110 Patients. Implant Dent., 19: 447-456.
VijayalakshmiI, R, Rajmohan, C. S., Deepalakshmi, D., & Sivakami, G. (2012). Use of platelet rich fibrin in a fenestration defect around an implant. J Indian Soc Periodontol., 16 (1): 108-112.
Wu, C. L., Lee, S. S., Tsai, C. H., Lu, K. H., Zhao, J. H., & Chang, Y. C. (2012). Platelet-rich fibrin increases cell attachment, proliferation and collagen-related protein expression of human osteoblasts. Aust Dent J., 57: 207-212.
Yilmaz, D., Dogan, N., Ozkan, A., Sencimen, M., Ora, B. E., & Mutlu, I. (2014). Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs. Acta Cir Bras, 29: 59-65.
Zhao, J. H., Tsai, C. H., & Chang, Y. C. (2011). Clinical and histologic evaluations of healing in an extraction socket filled with platelet-rich fibrin. J Dent Sci. 2011, 6 (2): 116-122.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Keven de Assis Fursel; José Lopes de Oliveira Neto; Mateus José de Sousa; Victor Hugo Lopes de Oliveira Moreira; Rubens Jorge Silveira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.