Peripheral odontogenic myxoma: Clinical case with a literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i6.15797

Keywords:

Odontogenic myxoma; Oral pathology; Dentistry; Oral cavity.

Abstract

Peripheral odontogenic myxoma (POM) is a rare and extra-osseous variant of odontogenic myxoma (OM), classified as a relatively rare benign odontogenic tumor, yet presenting locally aggressive behavior. The objective this manuscript is to report a case of POM in a 75-year-old patient, located in the right maxilla, and in addition, to perform a literature review of the data in relation to clinical, radiographic aspects, hypothesis of diagnosis, and treatment. A male patient, 75 years old, clinical examination constact the presence of a nodule, with a smooth surface, on the right upper alveolar ridge, measuring 20 x 25 mm, with a color similar to the mucosa, a softened consistency, involving teeth 14 and 15, and with an undetermined time of evolution was observed. The diagnostic hypothesis was a peripheral ossifying fibroma and differential diagnosis of peripheral giant cell lesion. An excisional biopsy was performed together with extraction of the involved teeth. Histopathological examination and histochemical reaction was confirm the histopathological diagnosis of POM. The reported case is extremely rare due to the clinical presentation of the lesion, causing bone resorption with tooth mobility. In addition, the age range of involvement is very different from that presented in the literature, between the second and fourth decade of life. The final diagnosis was very important, as it is a lesion with a great potential for recurrence, long-term follow-up should be more careful, and in case of recurrence, a new intervention must be performed.

References

Aytac-Yazicioglu, D., Eren, H., & Görgün, S. (2008). Peripheral odontogenic myxoma located on the maxillary gingiva: Report of a case and review of the literature. Oral and Maxillofacial Surgery, 12(3), 167–171. https://doi.org/10.1007/s10006-008-0122-8.

Chrcanovic, B. R., & Gomez, R. S. (2019). Odontogenic myxoma: An updated analysis of 1,692 cases reported in the literature. Oral Diseases, 25(3), 676–683. https://doi.org/10.1111/odi.12875

Elzay, R. P., & Dutz, W. (1978). Myxomas of the paraoral-oral soft tissues. Oral Surgery, Oral Medicine, Oral Pathology, 45(2), 246–254. https://doi.org/10.1016/0030-4220(78)90091-9.

Hill, T. L., Jones, B. E., & Park, K. H. (1990). Myxoma of the skin of a finger. Journal of the American Academy of Dermatology, 22(2), 343–345. https://doi.org/10.1016/0190-9622(90)70044-I.

Jain, V. K., & Reddy, S. N. (2013). Peripheral odontogenic myxoma of maxillary gingiva: A rare clinical entity. Journal of Indian Society of Periodontology, 17(5), 653–656. https://doi.org/10.4103/0972-124X.119287.

Kanitkar, S., Kamat, M., Tamagond, S., Varekar, A., & Datar, U. (2017). Peripheral odontogenic myxoma in a 12-year-old girl: A rare entity. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 43(3), 178–181. https://doi.org/10.5125/jkaoms.2017.43.3.178.

Kapoor, P., Gandhewar, T. M., Andrade, N. N., & Desai, R. S. (2015). Peripheral myxoma of the infratemporal region: An unusual case report. Journal of Oral Biology and Craniofacial Research, 5(3), 232–235. https://doi.org/10.1016/j.jobcr.2015.07.004.

Miettinen, M., Hockerstedt, K., Reitamo, J., & Totterman, S. (1985). Intramuscular myxoma - A clinicopathological study of twenty-three cases. American Journal of Clinical Pathology, 84(3), 265–272. https://doi.org/10.1093/ajcp/84.3.265.

Oliveira, S. V., Rocha, A. C., Ceccheti, M. M., Gallo, C. de B., & Alves, F. A. (2018). Odontogenic Myxoma in a Child treated with enucleation and curettage. Autopsy and Case Reports, 8(3). https://doi.org/10.4322/acr.2018.042.

Perrotti, V., Rubini, C., Fioroni, M., & Piattelli, A. (2006). Soft tissue myxoma: Report of an unusual case located on the gingiva. Journal of Clinical Periodontology, 33(1), 76–78. https://doi.org/10.1111/j.1600-051X.2005.00837.x

Raubenheimer, E. J., & Noffke, C. E. (2012). Peripheral Odontogenic Myxoma: A Review of the Literature and Report of Two Cases. Journal of Maxillofacial and Oral Surgery, 11(1), 101–104. https://doi.org/10.1007/s12663-011-0194-0

Shenoy, V. S., Rao, R. A., Prasad, V., Kamath, P. M., & Rao, K. S. (2014). Soft tissue myxoma- a rare differential diagnosis of localized oral cavity lesions. Journal of Clinical and Diagnostic Research, 8(12), KD01–KD02. https://doi.org/10.7860/JCDR/2014/10189.5288.

Shimoyama, T., Horie, N., Kato, T., Tojo, T., Nasu, D., Kaneko, T., & Ide, F. (2000). Soft tissue myxoma of the gingiva: report of a case and review of the literature of soft tissue myxoma in the oral region. Journal of Oral Science, 42(2), 107–109. https://doi.org/10.2334/josnusd.42.107.

Singh, P., & Davies, H. T. (2013). An ectopic tooth concealing an odontogenic myxoma. Dental Update, 40(1), 32–35. https://doi.org/10.12968/denu.2013.40.1.32.

Tasnime, S., Saxena, C., Bansal, V., & Wadhwan, V. (2016). Peripheral odontogenic myxoma. Indian Journal of Dental Research, 27(4), 437–440. https://doi.org/10.4103/0970-9290.191896.

Tse JJ, Vander S. (1985). The soft tissue myxoma of the head and neck region--report of a case and literature review. Head Neck Surg. 7(6):479-483. doi:10.1002/hed.2890070608.

Downloads

Published

29/05/2021

How to Cite

NUNES, C. E. N. .; MORAIS , A. D. A. .; LIMA, J. V. M. de .; CHAVES, F. N. .; SAMPIERI, M. B. da S. .; OLIVEIRA, D. H. I. P. de . Peripheral odontogenic myxoma: Clinical case with a literature review. Research, Society and Development, [S. l.], v. 10, n. 6, p. e26910615797, 2021. DOI: 10.33448/rsd-v10i6.15797. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/15797. Acesso em: 20 jun. 2021.

Issue

Section

Health Sciences