Treatment of multiple recidivant basal cell carcinom: Importance of early screening and patient's quality of life




Basal cell carcinoma; Humanization of assistance ; General surgery; Quality of life.


BCC is the most common non-melanoma skin tumor in Brazil and also the most benign, with small metastatic capacity and relative potential for local tissue destruction. It originates from basal cells of the epidermis and also from different parts of the follicular apparatus that have undergone chronic action of ultraviolet radiation. The study was justified due to the importance of BCC in the current medical scenario, as this condition is recurrent and can cause numerous losses to the patient, whether organic or psychosocial. Therefore, it requires better therapeutic methodology and early screening. 65-year-old male ACCA patient comes to the dermatological office with at least five skin lesions characteristic of BCC that have evolved for more than 10 years in frontooccipital regions (0.5x0.3 cm), pinna (1.5x1.0 cm) ), upper limbs (0.7x0.4 cm) and two on the anterior side of the right lower limb (1.0x0.6 cm). Refers to family and personal history of recurrent skin tumors and reports living social stigma resulting from the disease. Surgical excision with free margins and primary closure was performed, except in the leg region, in which skin grafting from the groin region was performed with Brown's dressing. The sample of biological material collected was subjected to a histopathological study that proved the diagnostic hypothesis of BCC in varying degrees of differentiation. Currently, he is undergoing dermatological follow-up to follow the wound healing and reports satisfaction with the result obtained. BCC frequently appears in dermatological clinics and medical clinics as the main complaint of patients with a history of chronic photoexposure or with a family history of skin tumors requiring surgical treatment. It is important to encourage the habit of solar photoprotection, as well as the search for professionals trained in the early diagnosis of the disease in order to avoid both the onset and evolution of this condition and the need for extensive surgical intervention and the compromise of the patient's self-esteem.


Agra, G., Gouveia, B. L. A., Sousa, A. T. O., Costa, M. M. L., Oliveira, S. H. S., & Soares, M. J. G. (2015). Cuidados paliativos de enfermagem a paciente com carcinoma basocelular terebrante: estudo de caso. Journal of Nursing UFPE/Revista de Enfermagem UFPE, 9(11).

Aguiar, D., Melo, A., Melo, B., Fluhr, F., Wanderley, M., & Pontes, A. C. (2017). Tratamento cirúrgico de carcinoma basocelular do tipo esclerodermiforme e recidiva linfonodal: relato de caso. Semana de Pesquisa do Centro Universitário Tiradentes-SEMPESq-Alagoas, (5).

Almeida, M. A., Feroldi, M. R., Vianna, L. Z., & Parreira, E. B. (2020). Carcinoma basocelular areolar: um raro relato de caso. Jornal Brasileiro de Patologia e Medicina Laboratorial, 56.

Behan, J. W., Sutton, A., & Wysong, A. (2016). Management of Skin Cancer in the High-Risk Patient. Current treatment options in oncology, 17(12), 60.

Borgonjen, R. J., van Everdingen, J. J., Bruijnzeel-Koomen, C. A., van de Kerkhof, P. C., & Spuls, P. I. (2015). A national study on adherence to a basal cell carcinoma guideline; development of a tool to assess guideline adherence. The British journal of dermatology, 172(4), 1008–1013.

Drucker, A. M., Adam, G. P., Rofeberg, V., Gazula, A., Smith, B., Moustafa, F., Weinstock, M. A., & Trikalinos, T. A. (2018). Treatments of Primary Basal Cell Carcinoma of the Skin: A Systematic Review and Network Meta-analysis. Annals of internal medicine, 169(7), 456–466.

González, A. R., Londoño, Á. M., Mejía, M. E., Gaitan, M., Pistone, M., & Etchichury, D. (2016). Carcinoma basocelular metastásico. Experiencia de tres casos tratados con cirugía de Mohs. Dermatología Revista Mexicana, 60(4), 348-353.

Hachmann, C. (2018). Carcinoma basocelular em lábio superior: relato de caso. Ação Odonto.

Hoorens, I., Vossaert, K., Ongenae, K., & Brochez, L. (2016). Is early detection of basal cell carcinoma worthwhile? Systematic review based on the WHO criteria for screening. The British journal of dermatology, 174(6), 1258–1265.

Jacobsen, A. A., Aldahan, A. S., Hughes, O. B., Shah, V. V., & Strasswimmer, J. (2016). Hedgehog Pathway Inhibitor Therapy for Locally Advanced and Metastatic Basal Cell Carcinoma: A Systematic Review and Pooled Analysis of Interventional Studies. JAMA dermatology, 152(7), 816–824.

Leyva, E. P., Ochoa, K. B., Guerra, O. P., Rivero, I. B., & Martinez, M. V. S. (2016). Interferones una opción terapéutica moderna en el tratamiento de los carcinomas basocelulares. Correo Científico Médico de Holguín, 20(2), 275-291.

Lin, Y., Chahal, H. S., Wu, W., Cho, H. G., Ransohoff, K. J., Song, F., Tang, J. Y., Sarin, K. Y., & Han, J. (2017). Association study of genetic variation in DNA repair pathway genes and risk of basal cell carcinoma. International journal of cancer, 141(5), 952–957.

Liu, N., Liu, G. J., & Liu, J. (2017). Genetic association between TNF-α promoter polymorphism and susceptibility to squamous cell carcinoma, basal cell carcinoma, and melanoma: A meta-analysis. Oncotarget, 8(32), 53873–53885.

Loney, T., Paulo, M. S., Modenese, A., Gobba, F., Tenkate, T., Whiteman, D. C., Green, A. C., & John, S. M. (2021). Global evidence on occupational sun exposure and keratinocyte cancers: a systematic review. The British journal of dermatology, 184(2), 208–218.

MacDonald D. S. (2015). A systematic review of the literature of nevoid basal cell carcinoma syndrome affecting East Asians and North Europeans. Oral surgery, oral medicine, oral pathology and oral radiology, 120(3), 396–407.

Murray, C., Sivajohanathan, D., Hanna, T. P., Bradshaw, S., Solish, N., Moran, B., Hekkenberg, R., Wei, A. C., & Petrella, T. (2019). Patient Indications for Mohs Micrographic Surgery: A Systematic Review. Journal of cutaneous medicine and surgery, 23(1), 75–90.

Nigro, M. H. M. F., Brandão, L. S. G., Coelho, A. P. C. P., da Motta, L. M., & Júnior, I. B. (2015). Estudo epidemiológico do carcinoma basocelular no período de 2010 a 2013 em um hospital de referência em dermatologia na cidade de Bauru, São Paulo. Surgical & Cosmetic Dermatology, 7(3), 232-235.

Oliveira, J. L. R. D., Coutinho, M. C. R., Ribeiro, R. S. D., & Cavalcanti, Z. D. R. (2018). Prevalência de depressão em idosos com câncer em hospital de referência do Recife.

Oliveira, M. A. P., Velarde, G. C., & Moreira De Sá, R. A. (2015). Entendendo a pesquisa clínica V: relatos e séries de casos. Femina [Internet], 43(5): 235–8.

Praia, A. C. D. S., & de Figueiredo, P. H. M. (2020). Carcinoma basocelular pigmentado: Relato de caso. BWS Journal, 3, 1-8.

Quazi, S. J., Aslam, N., Saleem, H., Rahman, J., & Khan, S. (2020). Surgical Margin of Excision in Basal Cell Carcinoma: A Systematic Review of Literature. Cureus, 12(7), e9211.

Reiter, O., Mimouni, I., Dusza, S., Halpern, A. C., Leshem, Y. A., & Marghoob, A. A. (2019). Dermoscopic features of basal cell carcinoma and its subtypes: A systematic review. Journal of the American Academy of Dermatology, S0190-9622(19)33008-7. Advance online publication.

Silva, F. M., de Souza Borges, F. R., Lopes, R. B., de Carvalho, T. C. A., & Lima, C. S. (2018). As Dificuldades Encontradas Pelos Pacientes No Tratamento Do Câncer De Pele Não Melanoma Em Anápolis-Go. CIPEEX, 2, 1062-1062.

Simoneti, F., Cunha, L. O., Gomes, C. T. V., Novo, N. F., Portella, D. L., & Gonella, H. A. (2016). Perfil epidemiológico de pacientes com tumores cutâneos malignos atendidos em ambulatório de cirurgia plástica de serviço secundário no interior de São Paulo. Revista da Faculdade de Ciências Médicas de Sorocaba, 18(2), 98-102.

Thomson, J., Hogan, S., Leonardi-Bee, J., Williams, H. C., & Bath-Hextall, F. J. (2021). Interventions for basal cell carcinoma: abridged Cochrane systematic review and grade assessments. The British journal of dermatology, 10.1111/bjd.19809. Advance online publication.

Xie, P., & Lefrançois, P. (2018). Efficacy, safety, and comparison of sonic hedgehog inhibitors in basal cell carcinomas: A systematic review and meta-analysis. Journal of the American Academy of Dermatology, 79(6), 1089–1100.e17.



How to Cite

SILVA, P. H. F.; ASSUNÇÃO, A. J. T.; MOURA, A. C.; PEREIRA, M. C. L.; JANUÁRIO, A. L. A. P.; DANTAS, H. M. N.; HOLANDA, S. M. M. S. C. de; NUNES , R. M. de O.; SILVA, L. A. dos S.; BARROS, M. M. de; REZENDE, E. M. S.; SANTOS, P. H. M. dos. Treatment of multiple recidivant basal cell carcinom: Importance of early screening and patient’s quality of life. Research, Society and Development, [S. l.], v. 10, n. 6, p. e43410615885, 2021. DOI: 10.33448/rsd-v10i6.15885. Disponível em: Acesso em: 14 jun. 2024.



Health Sciences