Profile severe acute respiratory syndrome cases obtained by a public health reference laboratory

Authors

DOI:

https://doi.org/10.33448/rsd-v10i6.16056

Keywords:

Influenza; SRAG; Laboratory Surveillance.

Abstract

Objective: To analyze the profile of notified SARS cases and results obtained by a Public Health Reference Laboratory. Methodology: This is a cross-sectional study, developed from the notification forms and notified results of SRAG obtained through the LACEN-GO Surveillance Nucleus. The Epi info 3.5.4 software was used to transcribe the results, analyze the variables contained in the notification form and the Chi-square test (x2). Results: 691 SRAG notification forms and their reported results were analyzed. The average age of the cases was 33 years, the main biological sample was the secretion of the oro and nasopharynx and for the identification of the viral etiology, the RT-PCR was used. Regarding the epidemiological profile, most of the cases were female, non-pregnant, had an education higher than 8 years, were not vaccinated and there was a need for the use of antiviral drugs. The main signs and symptoms were cough, fever and respiratory distress. The main comorbidity was chronic cardiovascular disease. There was a need for hospitalization, the main radiological pattern found was the interstitial infiltrate and the intensive care unit was used. The main viral etiologic agent diagnosed was the Influenza A / H1N1pdm09 virus. Conclusion: The epidemiological surveillance of Influenza through SARS Notification, including surveillance of SG in sentinel units, is an important tool for public health and has become the fundamental factor for the prevention, containment, surveillance and therapeutic management of patients.

References

Allard, R. et al. (2012). Invasive bacterial infections following influenza: a time-series analysis in Montréal, Canada, 1996- 2008. Oxford. 6(4), 268-275.

Breese, J. S.; Fry, A. M.; Sambara, S.; Cox, N. J. (2018). Inactivated Influenza Vaccines. In: Plotkin, S.; Orenstein, W.; Offit, P.; Eduwards, K. M. Plotkin´s Vaccines. Philadelphia: Saunders Elsevier, 456-488.

Bricks, L. F. et al. (2014). Influenza em crianças o que há de novo? Journal of Health and Biological Sciences. 3(2), 125-134.

Cavalieri, G. C. et al. (2016). Perfil Epidemiológico dos Casos de Influenza A em Santa Catarina, Brasil no ano de 2012. Arq. Catarin Med. 45(2),79-90.

Cowling, B. J. et al. (2013). Comparative epidemiology ofhuman infections with avian Influenza A (H7N9) and A(H5N1) viruses in China. Lancet. 382(9887), 129-137.

Coloquhoun, A. J. et al. (1997). Effectiveness of influenza vaccine in reducing hospital admissions in people with diabetes. Epidemiology and Infection. 119(3), 335-341.

Falsey, A. R. et al. (2014). Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. The Journal Infectious Disease. 209(2), 1873-1881.

Fiebig, L. et al. (2011). Avian Influenza A (H5N1) in humans: new insights from a line list of World Health Organization confirmed cases. Euro Surveill. 16(32), 1-10.

Fiore, A. E. et al. (2015). Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2007. Morbidity and Mortality Weekly Report. 56, 1-24.

Freitas, F. T. et al. (2014). Reitas, F. T. Sentinel surveillance of influenza and other respiratory viruses, Brazil, 2000-2010. The Brazilian Journal of Infectious Disease. 17(1), 62-68.

Freitas, A. R. et al. (2013). Mortality associated with influenza in tropics, state of São Paulo, Brazil, from 2002 to 2011: the pre-pandemic, pandemic, and post-pandemic periods. Influenza Research and Treatment. 4(1), 20-28.

Jayasundara, K. et al. (2016). Natural attack rate of influenza in unvaccinated children and adults: a meta-regression analysis. BMC Infectious Disease. 1(2).

Jefferson, T. et al. (2014). Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BM. 314.

Lan, Y. et al. (2013). Epidemiology of pandemic Influenza A/H1N1 virus during 2009–2010 in Taiwan. Virus Res. 117(2), 46-54.

Lenzi, L. et al. (2011). Study of the relationship between sociodemographic characteristics and new Influenza A (H1N1). Braz J Infect Dis. 15(5), 457-467.

Maraví-Poma, E. et al. (2011). Severe 2009 H1N1 Influenza in pregnant women in Spain. Crit Care Med. 39(1), 945-951.

Mazon, L. M. et al. (2016). Perfil epidemiológico de pacientes com síndrome gripal e síndrome respiratória aguda grave. Sáude em Revista. 2(4).

Michels, B. et al. (2011). A systematic review of the evidence on the effectiveness and risks of inactivated influenza vaccines in different target groups. Vaccine. 29(49), 9159-9170.

Ministério da Saúde. (2015). Secretaria de Vigilância em Saúde. Departamento de Vigilância das Doenças Transmissíveis. Protocolo de tratamento de Influenza, 1(1), 1-41.

Ministério da Saúde. (2015). Protocolo de Manejo Clínico de Síndrome Respiratória Aguda Grave-SRAG. Brasília, DF.

Ministério da Saúde. (2017). Guia de vigilância em saúde. Volume único.

Mertz, D. et al. (2013). Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis. British Medical Journal. 347(3).

Ng, S. et al. (2016). The timeline of influenza virus shedding in children and adults in a household transmission study of influenza in Managua, Nicaragua. The Pediatric Infectious Disease Journal. 35(5), 582-586.

Nitsch-Ouch, A. et al. (2013). Clinical features and outcomes of influenza A and B infections in children. Advances in Experimental Medicine and Biology. 788(2), 89-96.

Paddock, C. D. et al. (2012). Myocardial injury and bacterial pneumonia contribute to the pathogenesis of fatal influenza B virus infection. The Journal of Infectious Disease. 205(6), 895-905.

Plans-rubió, P. The vaccination coverage required to establish herd immunity against influenza viruses. Preventive Medicine, v.55, n.1, p.72-77, 2012.

Schuelter-Trevisol, F. et al. (2012). Perfil epidemiológico dos casos de gripe A na região sul de Santa Catarina, Brasil, na pidemia de 2009. Rev Panam Salud Publica. 32(1), 82-86.

World Health Organization. (2018). Infection prevention and control of epidemic- and pandemic- prone acute respiratory infections in health care. Geneva: Word Health Organization, 2014a. http://www.who.int/mediacentre/factsheets/fs141/en/.

World Health Organization. (2018). Influenza (seasonal). Fact sheet. 2018; http://www.who.int/mediacentre/factsheets/fs211/en)

Published

08/06/2021

How to Cite

SILVEIRA, M. B.; OLIVEIRA, D. de L.; SILVA, N. M. da; FINOTTI, A.; PEREIRA, L. A.; MANRIQUE, E. J. C. . Profile severe acute respiratory syndrome cases obtained by a public health reference laboratory. Research, Society and Development, [S. l.], v. 10, n. 6, p. e51710616056, 2021. DOI: 10.33448/rsd-v10i6.16056. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/16056. Acesso em: 24 jun. 2021.

Issue

Section

Health Sciences