Endodontic Treatment in Patients Under Radiotherapy Treatment: Literature Review
DOI:
https://doi.org/10.33448/rsd-v10i7.16127Keywords:
Endodontics; Head and neck neoplasms; Radiotherapy.Abstract
The prevalence of head and neck cancer has been increasing more and more and is associated with pain, disfigurement, dysfunction, psychosocial suffering and death. Among the forms of treatment there are radiotherapy, chemotherapy, surgery, as well as their combination. One of the biggest complications of radiotherapy is osteoradionecrosis. It presents xerostomia, and consequently radiation caries, which appear due to a change in the oral microbiota, creating a more acidic environment. These microorganisms cause an inflammation inside the tooth that later develops into pulp necrosis. With this, the objective of this work is to carry out a review in the literature that shows how to perform an atraumatic endodontic treatment, highlighting the conduct for endodontic treatment in cancer patients and how to avoid osteoradionecrosis of the jaws. Search strategies were used in five databases: PubMed; Cochrane; LILACS; Web of Science; and Scopus, with the keywords: "head neck cancer", "root canal therapy", "endodontic treatment". The main reason for performing endodontic treatment is the fact that a more conservative treatment can be performed, being an alternative to avoid tooth extraction and reduce the possibility of causing osteonecrosis. In patients who are in the pre-radiotherapy treatment phase, the protocol suggests a normal treatment. In the phases during and after irradiation treatment, the cleaning of the channels must be non-traumatic. If a tooth has sufficient structure, compatible with a good prognosis for rehabilitation, but with an inflammatory lesion or irreversible pulp inflammation, endodontic treatment is ideal.
References
AlRahabi, M. K., & Ghabbani, H. M. (2018). Clinical impact of bisphosphonates in root canal therapy. Saudi medical journal, 39(3), 232–238. https://doi.org/10.15537/smj.2018.3.20923
Alterio, D., Marvaso, G., Ferrari, A., Volpe, S., Orecchia, R., & Jereczek-Fossa, B. A. (2019). Modern radiotherapy for head and neck cancer. Seminars in oncology, 46(3), 233–245. https://doi.org/10.1053/j.seminoncol.2019.07.002
Baumgartner, J. C., & Eggli, D. (1989). The use of bone imaging to detect a periapical lesion of endodontic origin. Journal of endodontics, 15(10), 493–495. https://doi.org/10.1016/s0099-2399(89)80032-9
Bodrumlu, E., Avsar, A., Meydan, A. D., & Tuloglu, N. (2009). Can radiotherapy affect the apical sealing ability of resin-based root canal sealers? Journal of the American Dental Association (1939), 140(3), 326–330. https://doi.org/10.14219/jada.archive.2009.0162
Brennan, M. T., Woo, S. B., & Lockhart, P. B. (2008). Dental treatment planning and management in the patient who has cancer. Dental clinics of North America, 52(1), 19–vii. https://doi.org/10.1016/j.cden.2007.10.003
Camargo, J. M. P. De.; Camargo, R. V. De.; Cintra, L. T. A.; Faria, F. D.; Consolaro, A.; Cao, D.; Leonardo, R. De T. (2021). Salto Evolutivo em Endodontia. Relato de caso. Research, Society and Development, 10(3), e44110313538 DOI: 10.33448/rsd-v10i3.13538.
Cox F. L. (1976). Endodontics and the irradiated patient. Oral surgery, oral medicine, and oral pathology, 42(5), 679–684. https://doi.org/10.1016/0030-4220(76)90218-8
Chow L. (2020). Head and Neck Cancer. The New England journal of medicine, 382(1), 60–72. https://doi.org/10.1056/NEJMra1715715
de Miranda, R. R., Silva, A., Dantas, N. O., Soares, C. J., & Novais, V. R. (2019). Chemical analysis of in vivo-irradiated dentine of head and neck cancer patients by ATR-FTIR and Raman spectroscopy. Clinical oral investigations, 23(8), 3351–3358. https://doi.org/10.1007/s00784-018-2758-6
Epstein, J. B., Thariat, J., Bensadoun, R. J., Barasch, A., Murphy, B. A., Kolnick, L., Popplewell, L., & Maghami, E. (2012). Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA: a cancer journal for clinicians, 62(6), 400–422. https://doi.org/10.3322/caac.21157
Faria, K. M., Brandão, T. B., Ribeiro, A. C., Vasconcellos, A. F., de Carvalho, I. T., de Arruda, F. F., Castro Junior, G., Gross, V. C., Almeida, O. P., Lopes, M. A., & Santos-Silva, A. R. (2014). Micromorphology of the dental pulp is highly preserved in cancer patients who underwent head and neck radiotherapy. Journal of endodontics, 40(10), 1553–1559. https://doi.org/10.1016/j.joen.2014.07.006
Ferraz, F. C., Simões, W., Rapaport, A., & Bozzo, R. O. (2004). O Uso de Localizador Apical Endodôntico em Pacientes Irradiados. Revista Gaúcha de Odontologia, 52 (3),157-160.
Grimaldi, N., Sarmento. V., Provedel, L ., & Almeida, D., Cunha, S.(2005). Conduta do cirurgião-dentista na prevenção e tratamento da osteorradionecrose: revisão de literatura. Revista Brasileira de Cancerologia, 51(4), 319-324.
Hommez, G. M., De Meerleer, G. O., De Neve, W. J., & De Moor, R. J. (2012). Effect of radiation dose on the prevalence of apical periodontitis--a dosimetric analysis. Clinical oral investigations, 16(6), 1543–1547. https://doi.org/10.1007/s00784-011-0665-1
Kaptan, F., Kazandag, M. K., & Iseri, U. (2013). Treatment of bisphosphonate related osteonecrosis following root canal therapy at the 1-year follow-up: report of two cases. Therapeutics and clinical risk management, 9, 477–482. https://doi.org/10.2147/TCRM.S52630
Kataoka, S. H., Setzer, F. C., Fregnani, E. R., Pessoa, O. F., Gondim, E., Jr, & Caldeira, C. L. (2012). Effects of 3-dimensional conformal or intensity-modulated radiotherapy on dental pulp sensitivity during and after the treatment of oral or oropharyngeal malignancies. Journal of endodontics, 38(2), 148–152. https://doi.org/10.1016/j.joen.2011.09.022
Kuroshima, S., Sasaki, M., & Sawase, T. (2019). Medication-related osteonecrosis of the jaw: A literature review. Journal of oral biosciences, 61(2), 99–104. https://doi.org/10.1016/j.job.2019.03.005
Kyrgidis, A., Arora, A., Lyroudia, K., & Antoniades, K. (2010). Root canal therapy for the prevention of osteonecrosis of the jaws: an evidence-based clinical update. Australian endodontic journal: the journal of the Australian Society of Endodontology Inc, 36(3), 130–133. https://doi.org/10.1111/j.1747-4477.2010.00280.x
Lieshout, H. F., & Bots, C. P. (2014). The effect of radiotherapy on dental hard tissue--a systematic review. Clinical oral investigations, 18(1), 17–24. https://doi.org/10.1007/s00784-013-1034-z
Loureiro, C.; Seron, M. A.; Braga, G. P. De A.; Silva, C. C. Da; Jacinto, R. C.; Sivieri-Araujo, G.; Duque, C.; Cintra, L. T. A.; Gomes-Filho, J. E. (2021). Influência da infecção viral no processo de reparo das lesões periapicais: uma revisão narrativa. Research, Society and Development, 10(3), e14210313134,. 10.33448/rsd-v10i3.13134.
Martins, C. V., Leoni, G. B., Oliveira, H. F., Arid, J., Queiroz, A. M., Silva, L. A., & Sousa-Neto, M. D. (2016). Influence of therapeutic cancer radiation on the bond strength of an epoxy- or an MTA-based sealer to root dentine. International endodontic journal, 49(11), 1065–1072. https://doi.org/10.1111/iej.12556
Novais, V. R., Soares, P. B., Guimarães, C. M., Schliebe, L. R., Braga, S. S., & Soares, C. J. (2016). Effect of Gamma Radiation and Endodontic Treatment on Mechanical Properties of Human and Bovine Root Dentin. Brazilian dental journal, 27(6), 670–674. https://doi.org/10.1590/0103-6440201601267
Paiola, F. G., Lopes, F. C., Mazzi-Chaves, J. F., Pereira, R. D., Oliveira, H. F., Queiroz, A. M., & Sousa-Neto, M. D. (2018). How to improve root canal filling in teeth subjected to radiation therapy for cancer. Brazilian oral research, 32, e121. https://doi.org/10.1590/1807-3107bor-2018.vol32.0121
Rosales, A. C., Esteves, S. C., Jorge, J., Almeida, O. P., & Lopes, M. A. (2009). Dental needs in Brazilian patients subjected to head and neck radiotherapy. Brazilian dental journal, 20(1), 74–77. https://doi.org/10.1590/s0103-64402009000100013
Ruggiero, S. L., Dodson, T. B., Fantasia, J., Goodday, R., Aghaloo, T., Mehrotra, B., O'Ryan, F., & American Association of Oral and Maxillofacial Surgeons (2014). American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update. Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, 72(10), 1938–1956. https://doi.org/10.1016/j.joms.2014.04.031
Sarathy, A. P., Bourgeois, S. L., Jr, & Goodell, G. G. (2005). Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: two case reports. Journal of endodontics, 31(10), 759–763. https://doi.org/10.1097/01.don.0000182737.09980.2c
Vissink, A., Jansma, J., Spijkervet, F. K., Burlage, F. R., & Coppes, R. P. (2003). Oral sequelae of head and neck radiotherapy. Critical reviews in oral biology and medicine: an official publication of the American Association of Oral Biologists, 14(3), 199–212. https://doi.org/10.1177/154411130301400305
Zecha, J. A., Raber-Durlacher, J. E., Nair, R. G., Epstein, J. B., Sonis, S. T., Elad, S., Hamblin, M. R., Barasch, A., Migliorati, C. A., Milstein, D. M., Genot, M. T., Lansaat, L., van der Brink, R., Arnabat-Dominguez, J., van der Molen, L., Jacobi, I., van Diessen, J., de Lange, J., Smeele, L. E., Schubert, M. M., & Bensadoun, R. J. (2016). Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 24(6), 2781–2792. https://doi.org/10.1007/s00520-016-3152-z
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