Use of vitamin D to decrease cardiovascular risk in patients with type II diabetes mellitus: A Systematic Review
DOI:
https://doi.org/10.33448/rsd-v10i7.16862Keywords:
Vitamin D; Cardiovascular disease; Diabetes mellitus.Abstract
Introduction: Diabetes mellitus is an increasingly prevalent disease in the modern world, being highly related to genetic and behavioral factors, causing numerous public health problems. Objective: analyze the use of vitamin D in order to reduce cardiovascular risk in patients with type 2 diabetes mellitus. Methods: A systematic review of the literature was performed. To prepare the study, national and international data were searched and the eligibility criteria were chosen considering the language of the article (English and Portuguese), complete texts and published in the last 10 years. In sequence, from the reading of the titles and subsequent analysis of the abstracts, the final sample consisted of 13 publications. Results: A low number of publications was detected, however, it was found that vitamin D and its analogs have a direct efficacy on the markers used to predict the cardiovascular risk of patients even though they still have doubts about their mechanisms of action. Conclusions: Intervention with vitamin D shows good results regarding the reduction of cardiovascular risk markers in diabetic patients. However, more research should be carried out to better clarify the correlation of vitamin D levels and the reduction of cardiovascular events, in addition to better their physiological mechanisms, therapeutic strategies and their effects on the most diverse population profiles in order to develop effective and conclusive interventions.
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