Sutton's disease: Diagnosis, management and therapeutic options

Authors

DOI:

https://doi.org/10.33448/rsd-v10i10.18056

Keywords:

Aphthous stomatitis; Treatment; Pathology; Oral ulcers.

Abstract

Recurrent aphthous stomatitis (RAS) is a more common disorder of the oral mucosa and is characterized by a well-defined, painful ulcerated lesion with a necrotic center, raised borders, and an erythematous halo. However, the characterization of a specific etiological agent for this condition has not yet occurred. RAS has three main forms, with the smallest RAS being the most common in the oral cavity, which are painful and well-defined ulcerations that heal within 10 to 14 days. Herpetiformis, which has several lesions and can coalesce between 7 and 10 days, finally we have the longest RAS, which can last for more than 6 weeks and can leave scars. Methodology: This study is a qualitative and descriptive case report, bringing relevant data from the literature. The ethical principles of the Declaration of Helsinki were respected and the patient signed the “Informed Consent Form” to participate in the research. The aim of this study was to report a case of RAS in a 41-year-old male patient with Sutton's disease, presenting multiple necrotizing ulcers within 9 years of recurrence. Conclusion: As the etiology of RAS is still unknown and a common and recurrent disorder in the oral cavity, current treatment is diversified and focuses on relieving the symptoms of the disease, ranging from the use of natural products, topical use, anti-inflammatory drugs, immunomodulators and low power laser application.

References

Alfonso Valdés, M. E. (2016). Síndrome de Behcet. Revista Cubana de Hematología, Inmunología y Hemoterapia, 32(3), 301-315.

Costa, G. B., & Castro, J. F. (2013). Etiologia e tratamento da estomatite aftosa recorrente-revisão de literatura. Medicina (Ribeirão Preto), 46(1), 1-7.

da Rocha Curvelo, J. A., de Carvalho Ferreira, D., de Carvalho, F. C. R., & Janini, M. E. R. (2008). Úlceras aftosas recorrentes e sua possível associação ao estresse. Revista de Ciências Médicas e Biológicas, 7(1), 67-75.

de Araújo, A. R. M. D. (2013). Abordagem diagnóstica da Aftose oral recorrente.

de Souza Tolentino, E., Romanichen, I. M. M., Bessani, A., Nicácio, L. A., & Ferreira, G. Z. (2018). Manifestações bucais e considerações gerais da síndrome de Behçet: relato de caso. Revista da Faculdade de Odontologia-UPF, 23(3), 322-328.

Fávaro, D. M., & Martins, G. (2005). Ulceração aftosa recorrente em crianças: revisão. Archives of Oral Research, 1(3).

Fitzpatrick, S. G., Cohen, D. M., & Clark, A. N. (2019). Ulcerated lesions of the oral mucosa: clinical and histologic review. Head and neck pathology, 13(1), 91-102.

Fraiha, P. M., Bittencourt, P. G., & Celestino, L. R. (2002). Estomatite aftosa recorrente: revisão bibliográfica. Revista Brasileira de Otorrinolaringologia, 68(4), 571-578.

Gonzaga, H. F. D. S., Gonzaga, L. H. D. S., Costa, C. A. D. S., Spolidorio, L. C., Osaki, L., & Naka, P. M. (2013). Avaliação sistêmica de paciente portador de ulceração aftosa recorrente. Revista de Odontologia da UNESP, 24(2), 253-262.

Gürkan, A., Özlü, S. G., Altıaylık‐Özer, P., Kurtul, B. E., Karacan, C. D., & Şenel, S. (2015). Recurrent aphthous stomatitis in childhood and adolescence: a single‐center experience. Pediatric dermatology, 32(4), 476-480.

Huling, L. B., Baccaglini, L., Choquette, L., Feinn, R. S., & Lalla, R. V. (2012). Effect of stressful life events on the onset and duration of recurrent aphthous stomatitis. Journal of oral pathology & medicine, 41(2), 149-152.

Lin, K. C., Tsai, L. L., Ko, E. C., Yuan, K. S. P., & Wu, S. Y. (2019). Comorbidity profiles among patients with recurrent aphthous stomatitis: A case–control study. Journal of the Formosan Medical Association, 118(3), 664-670.

Najeeb, S., Khurshid, Z., Zohaib, S., Najeeb, B., Qasim, S. B., & Zafar, M. S. (2016). Management of recurrent aphthous ulcers using low-level lasers: a systematic review. Medicina, 52(5), 263-268.

Neville, B. (2011). Patologia oral e maxilofacial (12a ed.). Elsevier Brasil.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica.[e-book]. Santa Maria. Ed (pp. 3-9). UAB/NTE/UFSM. Disponível em: https://repositorio. ufsm. br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica. pdf.

Pereira, K. M. A., Rocha, D. A. P., Galvão, H. C., & Freitas, R. D. A. (2013). Ulceração aftosa recorrente: revisão dos conceitos atuais. Revista de Odontologia da UNESP, 35(1), 61-67.

Reolon, L. Z., Rigo, L., Conto, F. D., & Cé, L. C. (2017). Impacto da laserterapia na qualidade de vida de pacientes oncológicos portadores de mucosite oral. Revista de Odontologia da UNESP, 46(1), 19-27.

Rioboo Crespo, M., & Bascones Martínez, A. (2011). Aftas de la mucosa oral. Avances en Odontoestomatología, 27(2), 63-74.

Ship, J. A. (1996). Recurrent aphthous stomatitis: an update. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 81(2), 141-147.

Silva, L. F., de Carvalho, L. F. L., de Souza Gorjão, P., dos Santos, A. P. P., da Silva, V. E. S., & Fernandes, V. M. P. (2019). O papel do cirurgião-dentista no diagnóstico e tratamento de lesões orais associadas a doenças sistêmicas inflamatórias. Revista Interdisciplinar, 12(2), 121-125.

Sonia, K. H., & Catherine, E. (2020). Sutton's Disease and Vitamin Deficiency: Diagnostic and Therapeutic Difficulties. About a Clinical Case at the University Teaching Hospital Center of Yaounde.

Tarakji, B., Gazal, G., Al-Maweri, S. A., Azzeghaiby, S. N., & Alaizari, N. (2015). Guideline for the diagnosis and treatment of recurrent aphthous stomatitis for dental practitioners. Journal of international oral health: JIOH, 7(5), 74.

Vaillant, L., & Samimi, M. (2016). Aphtes et ulcérations buccales. La Presse Médicale, 45 (2), 215–226. doi: 10.1016 / j.lpm.2016.01.005.

Vieira, A. C. F., do Carmo, C. D. S., Vieira, G. M. B., Lima, L. A., da Cruz, M. C. F. N., & ferreira Lopes, F. (2015). Tratamento da estomatite aftosa recorrente: uma revisão integrativa da literatura. Revista da Faculdade de Odontologia-UPF, 20(3).

Published

04/08/2021

How to Cite

DELAMURA, I. F. .; SOUZA, M. de C. .; VIOTTO, A. H. A. .; BARRA, R. H. D. .; SILVA, L. F. A. da .; BIZELLI, V. F. .; BAGGIO , A. M. P. .; FERRIOLLI , S. C. .; PONZONI , D.; BASSI , A. P. F. . Sutton’s disease: Diagnosis, management and therapeutic options. Research, Society and Development, [S. l.], v. 10, n. 10, p. e06101018056, 2021. DOI: 10.33448/rsd-v10i10.18056. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18056. Acesso em: 12 nov. 2024.

Issue

Section

Health Sciences