Low-grade polymorphic adenocarcinoma: Atypical case report in the lower retromolar region of the young patient

Authors

DOI:

https://doi.org/10.33448/rsd-v10i9.18461

Keywords:

Adenocarcinoma; Salivary Glands; Adenoma.

Abstract

Low-grade polymorph adenocarcinoma (APBG) is a rare malignant neoplasm in the minor salivary gland. It is prevalent in females between the sixth and seventh decade of life. It usually starts asymptomatically, with slow growth and low aggressiveness, and the palate is the most frequent site. Cystic adenoid carcinoma and pleomorphic adenoma are the most frequent lesions that make a differential diagnosis with this neoplasm. Initial therapy should consist of complete surgical excision, with the possibility of association with radiotherapy treatment, with a favorable prognosis depending on the time of diagnosis. This paper aims to report a clinical case of low-grade polymorph adenocarcinoma in a 34-year-old female patient in the lower left alveolar ridge region. Reports of APBG in the posterior inferior alveolar ridge and in patients in the 3rd decade of life are extremely scarce in the specialized literature. It is extremely important for the dentist to know about the malignancies that can affect the oral cavity. Correct diagnosis and the establishment of an ideal clinical approach are essential for the patient's life expectancy and good prognosis.

References

Abu El-Naaj, I., Leiser, Y., Wolff, A., Peled, M. (2011). Polymorphous low grade adenocarcinoma: case series and review of surgical management. J Oral Maxillofac Surgery, 69, 1967-72.

Araujo, V., C., Passador-Santos, F., Turssi, C., Soares, A., B., Araujo, N., S. (2013). Polymorphous low-grade adenocarcinoma: an analysis of epidemiological studies and hints or pathologists. Diagn Pathol, 6, 1-8.

Barnes, L., Everson, J., W., Reichart, P., Sidransky, D. (2005). Wased Health Organization Classification of Tumors. Pathology and genetics of head and neck tumors. International Agency for research on cancer.

Baroni, Júnior, D., Liutti, V., T., Gama, R., R. (2008). Estudo retrospectivo de pacientes portadores de neoplasias de glândulas salivares: levantamento de 75 casos. Rev Med Res, 10(1), 16-24.

Buchner, A., Merrell., P., W., Carpenter, W., M. (2007). Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med, 36, 207-14.

B., W., Damm, D., D., Allen, C., M., Bouquot, J., E. (2009). Patologia oral e maxilofacial. 3ª ed. Rio de Janeiro, Elsevier.

Carboni, S., S., C., M. (2011). Padrão de expressão das gtpases RHO em adenoma pleomórfico de parótida. Universidade Federal do Triangulo Mineiro.

Fava, A., S., (2001). Diagnóstico, estadiamento e tratamento cirúrgico dos tumores malignos das glândulas salivares. Tratado de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia. São Paulo, Atheneu (pp.791-812).

Fife, T., A., Smith, B., Sullivan, C., A., Browne, J., D., Waltonen, J., D. (2013) Polymorphous low-grade adenocarcinoma: a 17 patient case series. Am J Otolaryngol, 34, 445-8.

J., Á., Ciulba, J., J., Jordan, R., C., K. (2008). Patologia Oral, correções clínico patológicas. 5ª Ed. Saunders Elsevier, Rio de Janeiro.

Jones, A., V., Craig, G., T., Speight, P., M., Franklin, C., D. (2008). The range and demographics of salivary gland tumors diagnosed in a UK population. Oral Oncol, 44(4), 407-17.

J., T., Thompson, L., D., R., Frommelt, R., A., Wenrig, B., M., Kessler, H., P., (1999). Polymorphous Low - Grad Adenocarcinoma a clinicopathologic study of 164 cases. American cancer society, 86(2), 207-219.

Lima, S., S., Soares, A., F., Amorim, R., F., B., Freitas, R., A. (2005). Perfil epidemiológico das neoplasias de glândulas salivares: análise de 245 casos. Rev Bras Otorrinolaringol, 71(3), 335-40.

Loiola, R., S., Matos, F., R., Nonaka, C., F., W., Lopes, F., F., Cruz, M., C., F., N. (2009). Perfil epidemiológico das neoplasias de glândulas salivares diagnosticadas em São Luís-MA. J Bras Patol Med Lab, 45(5), 413-20.

M., A., Wenig, B., M. (2009). Classificação de Tumores da Organização Mundial de Saúde. Genética e Patologia dos Tumores de Cabeça e de Pescoço. Ed. Santos. Gen/Grupo Editorial Nacional.

Mc., Hugh, Jonathan, B., M., D., V., Daniel, W., M., D., Barnes, E., Leon, M., D. (2009). Update on Selected Salivary Gland Neoplasms. Archives of Pathology e Laboratory Medicine, 1763-74.

M., C., Penna, K., Vinaski, M. (2000). Polymorphous Low – Grade Adenocarcinoma of the oral cavity. New York State Dental Journal, 28-32.

Milsa, Sarmento, D., J., S., Silveira, E., J., D., Oliveira, I., C., P., Costa, A., L., L. (2010). Adenocarcionoma polimorfo de baixo grau: relato de um caso adicional e uma atualização dos principais aspectos sobre seu diagnóstico. Rev. Odontol UNESP, 311-315.

M., S., Sabri, A., N., Lewis, J., E., Olsen, K., D. (2006). Retrospective study and review of polymorphous low-grade adenocarcinoma. Laryngoscope, 116, 2145-9.

Neville, B., W., Damm, D., D., Allen, C., M., Bouquot, J., E. (2008). Patologia oral & maxillofacial. 2ª Ed. Guanabara Koogan, Rio de Janeiro.

O’ Rourke, A., K., Gourin, C., G., Wade, Z., K., Hessler, R., B. (2006). Polymorphous Low – Grade Adenocarcinoma of the parotid gland. Ear, Nose e Thoat Journal, 669-71.

S., Kumar, C., A., Raghav, N. (2011). Polymorphous Low- Grade Adenocarcinoma of the Palate: Report of a case and Review of Literature. International journal of Head and Nick Surgery, 57-60.

Seethala, R., R., Johnson, J., T., Barnes, E., L., Myers, E., N. (2010). Polymorphous low-grade adenocarcinoma: the University of Pittsburgh experience. Arch Otolaryngol Head Neck Surg, 136, 385-92.

Soames, J., V., Southam, J., C. (2008). Patologia Oral. 4 Ed. Editora Gen/Guanabara Koogan, Rio de Janeiro.

Toida, M., Shimokawa, K., Makita, H., Kato, K., Kobayashi, A., Kusunoki, Y. (2005). Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. Int J Oral Maxillofac Surg, 34, 528-32.

Published

03/08/2021

How to Cite

RODRIGUES, L. R. S.; PEREIRA, C. M. Low-grade polymorphic adenocarcinoma: Atypical case report in the lower retromolar region of the young patient . Research, Society and Development, [S. l.], v. 10, n. 9, p. e59910918461, 2021. DOI: 10.33448/rsd-v10i9.18461. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18461. Acesso em: 23 sep. 2021.

Issue

Section

Health Sciences