Intra-articular mesenchymal stem cell therapy on a joint capsule rupture in a horse – Case report
DOI:
https://doi.org/10.33448/rsd-v10i12.20370Keywords:
Tibiotarsal joint; Lameness; Totipotent cells; Adjuvant therapy.Abstract
Joint capsule rupture is an uncommon pathology that leads to intense pain, lameness and is related to the athletic performance impossibility of the animal. This pathology presents controversial therapeutic protocols in the equine clinic and surgery. Therefore, this study aimed to report the use of mesenchymal stem cells associated with arthroscopy and rehabilitation to improve the treatment of joint capsule rupture in equine. A three-year-old, male, Quarter Horse, presenting grade 5 lameness, with four months of evolution, was diagnosed with tibiotarsal joint capsule rupture. The patient underwent arthroscopic surgery, received an intra articular application of mesenchymal stem cells, and a rehabilitation protocol was performed. One year after the treatment and rehabilitation, the horse reestablished its athletic performance, thus indicating the success of the therapy using mesenchymal stem cells associated with surgical treatment and rehabilitation.
References
AAEP, A. A. of E. P. (2018). LAMENESS EXAMS: Evaluating the Lame Horse. https://aaep.org/horsehealth/lameness-exams-evaluating-lame-horse
Barker, W. H. J., Smith, M. R. W., Minshall, G. J., & Wright, I. M. (2013). Soft tissue injuries of the tarsocrural joint: A retrospective analysis of 30 cases evaluated arthroscopically. Equine Veterinary Journal, 45(4), 435–441. https://doi.org/10.1111/j.2042-3306.2012.00685.x
Boller, C. E. P., & Lopes, F. de O. (2021). Injeção intra-articular de plasma rico em plaquetas para osteoartrite de joelho: parecer técnico científico a respeito do uso. Research, Society and Development, 10(1), e15710111606. https://doi.org/10.33448/rsd-v10i1.11606
Broeckx, S. Y., Seys, B., Suls, M., Vandenberghe, A., Mariën, T., Adriaensen, E., Declercq, J., Van Hecke, L., Braun, G., Hellmann, K., & Spaas, J. H. (2019). Equine Allogeneic Chondrogenic Induced Mesenchymal Stem Cells Are an Effective Treatment for Degenerative Joint Disease in Horses. Stem Cells and Development, 28(6), 410–422. https://doi.org/10.1089/scd.2018.0061
Bussoni, V., & Audigié, F. (2018). Equine stifle and tarsus. In Textbook of Veterinary Diagnostic Radiology (Elsevier, p. 1000).
Butler, J. A., Colles, C. M., Dyson, S. J., Kold, S. E., & W., P. P. (2017). Clinical Radiology of the Horse. In Wiley Blackwell (Issue 4). https://doi.org/10.1017/CBO9781107415324.004
Cunha, P. F. A., & Silva, R. B. B. da. (2021). Osteoartrite de joelho e o aspirado de medula óssea como escolha de tratamento - Uma revisão narrativa. Research, Society and Development, 10(7), e17410716391. https://doi.org/10.33448/rsd-v10i7.16391
Livesey, L., Schumacher, J., Sartin, E., Caldwell, M., Ziska, S., & Brock, K. (2009). Ruptured capsule of the elbow joint of a draught horse. Equine Veterinary Education, 21(7), 371–374. https://doi.org/10.2746/095777309X422988
Mcilwraith, C. W., Frisbie, D., Kawcak, C., & Weeren, R. V. (2016). Joint disease in the horse. In Journal of Equine Veterinary Science (Issue 9). https://doi.org/10.1016/s0737-0806(96)80178-x
Rich Redding, W. R. (2011). Ultrasound. In Lameness in horse (Sixth, pp. 338–376).
Taylor, S. E., Smith, R. K. W., & Clegg, P. D. (2007). Mesenchymal stem cell therapy in equine musculoskeletal disease: Scientific fact or clinical fiction? Equine Veterinary Journal, 39(2), 172–180. https://doi.org/10.2746/042516407X180868
Van Lent, P. L. E. M., & Van den Berg, W. B. (2013). Mesenchymal stem cell therapy in osteoarthritis: Advanced tissue repair or intervention with smouldering synovial activation? Arthritis Research and Therapy, 15(2), 1–2. https://doi.org/10.1186/ar4190
Yamada, A. L. M., Carvalho, A. de M., Moroz, A., Deffune, E., Watanabe, M. J., Hussni, C. A., Rodrigues, C. A., & Alves, A. L. G. (2013). Mesenchymal stem cell enhances chondral defects healing in horses. Stem Cell Discovery, 03(04), 218–225. https://doi.org/10.4236/scd.2013.34027
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Heitor Cestari; Joel Phillipe Costa e Souza; Carlos Alberto Hussni; Celso Antonio Rodrigues; Marcos Jun Watanabe; Ana Liz Garcia Alves
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.