Clinical management of thromboembolic events arising from complications of COVID-19: integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i13.21052

Keywords:

Venous thromboembolism; Pulmonary embolism; COVID-19; Clinical management.

Abstract

Objective: to identify how the clinical management of patients infected with COVID-19 who present pulmonary thromboembolism and/or venous thromboembolism occurs. Method: This is an integrative review, carried out by searching for articles in the VHL, LILACS, MEDLINE, CINAHL AND SCOPUS databases, with a temporal delimitation from November 2019 to March 2021. Results: 24 articles were included. Diagnosis occurs through D-dimer and fibrinogen. For drug therapy, low molecular weight heparin (LMWH) is administered, 30 mg/12h in 12h for prophylactic anticoagulation, staggered doses of LMWH with enoxaparin, 0.5 mg/kg twice a day for anticoagulation therapy and rivoxaban 10mg/day for post-discharge anticoagulation. Conclusion: Clinical management of TEP and VTE occurs through increased D-dimer or fibrinogen, with TEP confirmed by pulmonary angiography. For anticoagulation, LMWH is mostly used.

Author Biographies

Laura Dayane Gois Bispo, Universidade Federal de Sergipe

Academic in nursing. Federal University of Sergipe. Lizard, SE, Brazil.

Natan Martins Machado, Universidade Federal de Sergipe

Academic in medicine. Federal University of Sergipe, Lagarto, SE, Brazil.

Caio Lopes Pinheiro de Paula, Hospital de Urgências de Sergipe

Neurosurgeon. Sergipe Emergency Hospital, Aracaju, SE, Brazil.

Jussiely Cunha Oliveira, Universidade Federal de Sergipe

PhD in Health Sciences from the Federal University of Sergipe. Federal University of Sergipe, São Cristóvão, SE, Brazil.

Ingrid Melo Santos, Universidade Tiradentes

Pharmaceuticals. Tiradentes University, Aracaju, Sergipe, Brazil.

Fernanda Gomes de Magalhães Soares Pinheiro, Universidade Federal de Sergipe

PhD in Health Sciences from the Federal University of Sergipe. Federal University of Sergipe, Lagarto, SE, Brazil.

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Published

09/10/2021

How to Cite

BISPO, L. D. G.; MACHADO, N. M. .; PAULA, C. L. P. de .; OLIVEIRA, J. C.; SANTOS, I. M.; PINHEIRO, F. G. de M. S. . Clinical management of thromboembolic events arising from complications of COVID-19: integrative review. Research, Society and Development, [S. l.], v. 10, n. 13, p. e138101321052, 2021. DOI: 10.33448/rsd-v10i13.21052. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21052. Acesso em: 4 dec. 2021.

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Section

Health Sciences