Association of photobiomodulation and topic hyaluronidase in paclitaxel extravasation: case study

Authors

DOI:

https://doi.org/10.33448/rsd-v10i13.21470

Keywords:

Photobiomodulation; Photobiomodulation; Nursing care; Clinical protocols; Extravasation of Therapeutic and Diagnostic Materials; Nursing care; Clinical protocols; Extravasation of antineoplastic.

Abstract

Objective: To demonstrate the use of the association of photobiomodulation with topical hyaluronidase in paclitaxel extravasation. Method: Case study referring to the use of photobiomodulation and topical hyaluronidase in a paclitaxel extravasation that occurred in the oncology clinic of a university hospital. After 450 ml of paclitaxel infusion, the infusion pump stopped, edema on the site and displacement of part of the catheter from the puncture site was observed. Patient denied complaints of pain at the site and reported that he only observed the edema at the same time as the nursing team. The area was demarcated and presented an approximate measurement of 3.5 x 3.0 cm (height x width). Results: After verifying the extravasation, all necessary measures were taken, following the institutional protocol. Nine photobiomodulation points were performed using 1 joule/cm2 as energy density, then topical hyaluronidase 65 UTR/g was administered. The patient was instructed about home care. Conclusion: The association of FBM with topical hyaluronidase maintained the integrity of the patient's skin, not forming lesions resulting from extravasation.

References

Barbee, M. S., Owonikoko, T. K., & Harvey, R. D. (2014). Taxanes: vesicants, irritants, or just irritating?.Therapeutic advances in medical oncology, 6(1), 16–20. https://doi.org/10.1177/1758834013510546

Bonassa, E. M. A., & Gato, M. I. R. (2012). Terapêutica Oncológica para Enfermeiro e Farmacêuticos. (4th ed.). Editora Atheneu.

Chamusca, F. V., Reis, S. R. A., Lemaire, D., & Medrado, A. P. (2012). Mediadores do efeito sistêmico do processo inflamatório e terapias fotobiomoduladoras: uma revisão de literatura. Revista De Ciências Médicas E Biológicas, 11(1), 70–78. https://doi.org/10.9771/cmbio.v11i1.5705

Conselho Regional de Enfermagem de São Paulo (COREN). (2014). Parecer COREN-SP 009/2014. Utilização do Laser de Baixa Intensidade (LBI) pelo enfermeiro. Recuperado de https://portal.coren-sp.gov.br/sites/default/files/Parecer_009_Utilizacao_Laser_Baixa_Intensidade_LBI_por_enfermeiro.pdf

Conselho Regional de Enfermagem de São Paulo (COREN). (2018). Parecer COREN-SP 009/2018. Ementa: Laser Vermelho e Infra Vermelho. Recuperado de https://portal.coren-sp.gov.br/wp-content/uploads/2019/01/parecer-009-2018.pdf

Freitas, K. A. B. S. (2015). Estratégias para a administração segura de antineoplásicos [dissertação de mestrado]. Botucatu (BR): Universidade Estadual Paulista, Faculdade de Medicina de Botucatu. Recuperado de http://hdl.handle.net/11449/134240

Freitas, K. A. B. S., Minicucci, E. M., Bragnato, V. S., & Lizarelli, R. de F. Z. (2021). Association of different approaches to low level laser therapy in the treatment of surgical dehiscence of knee arthroplasty. Research, Society and Development, 10(11), e505101119757. https://doi.org/10.33448/rsd-v10i11.19757

Freitas, K. A. B. S., Minicucci, E. M., Lima, T. O., Silva, K. A. B., Menozzi, B. D., Silva, V. F. B., & Popim, R. C. (2021). Effects of photobiomodulation (low-intensity laser) on wound healing: an integrative review. Research, Society and Development, 10(11), e362101119821. https://doi.org/10.33448/rsd-v10i11.19821

Freitas, K. A. B. S., Oliveira de Lima, T., Beluomini de Castro, A., Batista da Silva, K. A., Passarelli Vigliassi, A., & Popim, R. C. (2020). Elaboração e implantação de protocolo de condutas no extravasamento de medicamentos não quimioterápicos. Saúde Coletiva (Barueri), 10(58), 3913–3922. https://doi.org/10.36489/saudecoletiva.2020v10i58p3913-3922

Gomes, C. F. G., & Schapochnik, A. (2017). O uso terapêutico do LASER de Baixa Intensidade (LBI) em algumas patologias e sua relação com a atuação na Fonoaudiologia. Distúrb Comun, 29(3), 570-578. https://doi.org/10.23925/2176-2724.2017v29i3p570-578

Instituto Nacional do Câncer (INCA). (2021). Quimioterapia. Recuperado de: https://www.inca.gov.br/tratamento/quimioterapia

Kapucu, S., Özkaraman, A. Ö., Uysal, N., Bagcivan, G., Şeref, F. Ç., & Elöz, A. (2017). Knowledge Level on Administration of Chemotherapy through Peripheral and Central Venous Catheter among Oncology Nurses. Asia-Pacific journal of oncology nursing, 4(1), 61–68. https://doi.org/10.4103/2347-5625.199081

Kreidieh, F. Y., Moukadem, H. A., & El Saghir, N. S. (2016). Overview, prevention and management of chemotherapy extravasation. World Journal Clinical Oncology, 1(7), 87-97. https://doi.org/10.5306/wjco.v7.i1.87

Lima, R. F. (2019). Elaboração e validação do Manual de Orientações sobre reações adversas a antineoplásicos para a Equipe de Enfermagem [dissertação de mestrado]. Natal (BR): Hospital das Clínicas de Porto Alegre. Recuperado de http://hdl.handle.net/10183/199303

Lima, T.O. (2019). Eficácia da laserterapia trasncutânea sobre efeitos adversos da quimioterapia: ensaio clínico randomizado. [dissertação de mestrado]. Botucatu (BR): Universidade Estadual Paulista, Faculdade de Medicina de Botucatu. Recuperado de http://hdl.handle.net/11449/190978

Lizarelli, R. F. Z. (2018). Reabilitação biofotônica orofacial: fundamentos e protocolos clínicos. Compacta

Maly, C., Fan, K. L., Rogers, G. F., Mitchell, B., Amling, J., Johnson, K., Welch, L., Oh, A. K., & Chao, J. W. (2018). A Primer on the Acute Management of Intravenous Extravasation Injuries for the Plastic Surgeon. Plastic and reconstructive surgery. Global open, 6(4), e1743. https://doi.org/10.1097/GOX.0000000000001743

Murayama, R., Oya, M., Abe-Doi, M., Oe, M., Komiyama, C., & Sanada, H. (2019). Characteristics of subcutaneous tissues at the site of insertion of peripheral infusion in patients undergoing paclitaxel and carboplatin chemotherapy. Drug discoveries & therapeutics, 13(5), 288–293. https://doi.org/10.5582/ddt.2019.01064

Patton, M. Q. (2002). Qualitative research & evaluation methods. (3rd ed.). Sage Publications.

Pelissa, A., & Nothaft, S. C. S. (2019). Extravasamento quimioterápico e as condutas adotadas pela equipe de enfermagem: uma revisão integrativa. Universidade Regional Integrada do Alto Uruguai e das Missões. Recuperado de http://repositorio.uricer.edu.br/handle/35974/252

Stanford, B. L., & Hardwicke, F. (2003). A review of clinical experience with paclitaxel extravasations. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 11(5), 270–277. https://doi.org/10.1007/s00520-003-0441-0

Vasques, C. I., Custódio, C. S., Goulart, C. B., Silveira, R. C. C. P., Santos, B. N., & Santos, K. R. M. (2018). Diretrizes Oncológicas: Acessos Vasculares em Oncologia (2nd ed.). DoctorPress

Published

21/10/2021

How to Cite

LIMA, T. O. de .; SANTOS, W. J. F. dos .; SPIN, M.; SARDELI, K. M. .; FREITAS, K. A. B. da S. . Association of photobiomodulation and topic hyaluronidase in paclitaxel extravasation: case study . Research, Society and Development, [S. l.], v. 10, n. 13, p. e553101321470, 2021. DOI: 10.33448/rsd-v10i13.21470. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21470. Acesso em: 27 dec. 2024.

Issue

Section

Health Sciences