Analysis of hepatic steatosis control in patients after bariatric surgery
DOI:
https://doi.org/10.33448/rsd-v10i14.22364Keywords:
Hepatic steatosis; Bariatric surgery; Control.Abstract
Purpose: To evaluate the association between the control of hepatic steatosis (HS) and the postoperative period of bariatric surgery in a private institution in Sergipe. Methodology: Retrospective observational and single-center study, with data collected through an online form, previously authorized by 57 patients, regardless of gender, with Class III or Class II obesity associated with comorbidities, who underwent bariatric surgery using the techniques of Vertical Gastrectomy (Gastric Sleeve) and Roux-en-Y Reduction Gastroplasty (Gastric Bypass) by videolaparoscopy, in a private institution in Aracaju/SE, between 2019 and 2021. After applying the exclusion criteria, 45 patients were analyzed. Data were analyzed using percentage frequency, Pearson and McNemar tests. It was adopted a significance level of 5%. Results: In the preoperative period, it was found a 66.7% prevalence of HS and in the postoperative period the prevalence was found to be 16.7%, with a reduction in the degree of the pathology to HS class I, verified through ultrasonographic examination. There was an 83.3% success rate in the patients with HS in the preoperative period. Of the 83.3%, there was a clinical improvement in 23 (67.6%) of those who underwent Gastric Sleeve surgery, as well as an improvement of 7 (63.6%) who underwent Gastric Bypass surgery. Conclusion: There was a significant association between bariatric surgery and the resolution of hepatic steatosis, regardless of the surgical technique used.
References
Bellentani, S., Saccoccio, G., Masutti, F., Crocè, L. S., Brandi, G., Sasso, F., Cristanini, G, & Tiribelli, C. (2000). Prevalence of and risk factors for hepatic steatosis in Northern Italy. Annals of internal medicine, 132(2), 112-117. doi: 10.7326/0003-4819-132-2-200001180-00004
Beymer, C., Kowdley, K. V., Larson A., Edmonson, P., Dellinger, E. P., & Flum, D. R. (2003). Prevalence and predictors of asymptomatic liver disease in patients undergoing gastric Bypass surgery. Arch Surg, 138(111), 1240-1244. doi:10.1001/archsurg.138.11.1240
Billeter, A. T., Senft, J., Gotthardt, D., Knefeli, P., Nickel, F., Schulte, T., Fischer, L., Nawroth, P. P., Büchler, M.W., & Müller-Stich, B. P. (2016). Combined non-alcoholic fatty liver disease and type 2 diabetes mellitus: sleeve gastrectomy or gastric bypass?—a controlled matched pair study of 34 patients. Obesity surgery, 26(8), 1867-1874. doi: 10.1007/s11695-015-2006-y
Bower, G., Toma, T., Harling, L., Jiao, L. R., Efthimiou, E., Darzi, A., Athanasiou, T., & Ashrafian, H. (2015). Bariatric surgery and non-alcoholic fatty liver disease: a systematic review of liver biochemistry and histology. Obesity surgery, 25(12), 2280-2289. doi: 10.1007/s11695-015-1691-x
Bult, M. J., van Dalen, T., & Muller, A. F. (2008). Surgical treatment of obesity. European journal of endocrinology, 158(2), 135–145. doi: 10.1530/EJE-07-0145
Castanha, C. R., Ferraz, A. A. B., Castanha, A. R., Belo, G. D. Q. M. B., Lacerda, R. M. R., & Vilar, L. (2018). Avaliação da qualidade de vida, perda de peso e comorbidades de pacientes submetidos à cirurgia bariátrica. Revista do Colégio Brasileiro de Cirurgiões, 45, e-20181864. doi: 10.1590/0100-6991e-20181864
Fakhry, T. K., Mhaskar, R., Schwitalla, T., Muradova, E., Gonzalvo, J. P., & Murr, M. M. (2019). Bariatric surgery improves nonalcoholic fatty liver disease: a contemporary systematic review and meta-analysis. Surgery for Obesity and Related Diseases, 15(3), 502-511. doi: 10.1016/j.soard.2018.12.002
Frare, L., Pantano Alves , D., Farias , I. R. ., Medeiros, G. M. de ., & Soares, C. F. de P. (2021). Associação de esteatose hepática em pacientes em pré-operatório de cirurgia bariátrica com apneia obstrutiva do sono. Research, Society and Development, 10(6), e36610615495. doi: 10.33448/rsd-v10i6.15495
Freire, M; & Pattussi, M. (2018). Tipos de estudo In Estrela, C. (Org.), Metodologia Científica: Ciência, Ensino, Pesquisa (pp. 187-188). São Paulo: Editora Artes Médicas.
Freitas, A. C. T. D., Freitas, D. T. D., Parolin, M. B., Campos, A. C. L., & Coelho, J. C. U. (2007). Doença hepática não-alcoólica: evolução após derivação gastrojejunal em Y-de-Roux pela técnica de fobi-capella. Arquivos de Gastroenterologia, 44, 49-53. doi:10.1590/S0004-28032007000100011
Froylich, D., Corcelles, R., Daigle, C., Boules, M., Brethauer, S., & Schauer, P. (2016). Effect of Roux-en-Y gastric bypass and sleeve gastrectomy on nonalcoholic fatty liver disease: a comparative study. Surgery for Obesity and Related Diseases, 12(1), 127-131. doi: 10.1016/j.soard.2015.04.004
Goldoni, M. B., Fontes, P. R. O., Guimarães, M. M., Diedrich-Neto, J. A., Nogueira, T., Teixeira, U. F., Giacomazzi, C. B., Kiss, G., Pioner, S. R., & Rodrigues, P. D. (2021). Bypass vs. Sleeve e seus resultados na doença hepática gordurosa não alcoólica: qual a melhor técnica?. ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), 33. doi: 10.1590/0102-672020200003e1549
Hachem, A, & Brennan, L. (2016). Quality of life outcomes of bariatric surgery: a systematic review. Obes Surg., 26(2), 395-409. doi: 10.1007/s11695-015-1940-z
Hafeez, S., & Ahmed, M. H. (2013). Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: a future treatment by choice or by chance?. Journal of obesity, 2013, 839275. doi: 10.1155/2013/839275
Junior, L. C. K., do Nascimento, R. R., Nazário, R. F., & Mick, H. (2015). Estudo ultrassonográfico da esteatose hepática no pré e pós-operatório de cirurgia bariátrica. Revista da AMRIGS, 59(3), 209-216. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-835414
Marceau, P., Biron, S., Hould, F. S., Marceau, S., Simard, S., Thung, S. N., & Kral, J. G. (1999). Liver pathology and the metabolic syndrome X in severe obesity. The Journal of Clinical Endocrinology & Metabolism, 84(5), 1513-1517. doi: 10.1210/jcem.84.5.5661
Meré, L. A. F., & Blanco, M. A. (2004). Obesidad y cirugía bariátrica: Implicaciones anestésicas. NutrHosp, 19(1), 33-44. https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112004000100007
Mummadi, R. R., Kasturi, K. S., Chennareddygari, S., & Sood, G. K. (2008). Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis. Clinical Gastroenterology and Hepatology, 6(12), 1396-1402. doi: 10.1016/j.cgh.2008.08.012
Raj, P. P., Gomes, R. M., Kumar, S., Senthilnathan, P., Karthikeyan, P., Shankar, A., & Palanivelu, C. (2015). The effect of surgically induced weight loss on nonalcoholic fatty liver disease in morbidly obese Indians:“NASHOST” prospective observational trial. Surgery for Obesity and Related Diseases, 11(6), 1315-1322. doi: 10.1016/j.soard.2015.02.006
Soler, G. L. N., Silva, A. W. S. M., Silva, V. C. G., & Teixeira, R. de J. (2008). Doença Hepática Gordurosa Não-Alcoólica: associação com síndrome metabólica e fatores de risco cardiovascular. Rev SOCERJ, 21(2), 94–100. http://sociedades.cardiol.br/socerj/revista/2008_02/a2008_v21_n02_a04Gisele.pdf
Vargas, V., Allende, H., Lecube, A., Salcedo, M. T., Baena-Fustegueras, J. A., Fort, J. M., Rivero, J., Ferrer, R., Catalán, R., Pardina, E., Ramón Y Cajal, S., Guardia, J., & Peinado-Onsurbe, J. (2012). Surgically induced weight loss by gastric bypass improves non alcoholic fatty liver disease in morbid obese patients. World journal of hepatology, 4(12), 382–388. doi: 10.4254/wjh.v4.i12.382
Wirth, K. M., Sheka, A. C., Kizy, S., Irey, R., Benner, A., Sieger, G., Simon, G., Ma, S., Lake, J., Aliferis, C., Leslie, D., Marmor, S., & Ikramuddin, S. (2020). Bariatric Surgery is Associated With Decreased Progression of Nonalcoholic Fatty Liver Disease to Cirrhosis: A Retrospective Cohort Analysis. Annals of surgery, 272(1), 32–39. doi: 10.1097/SLA.0000000000003871
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