Pathophysiological, clinical and treatment repercussions of Wernicke's Encephalopathy: a review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i16.23857

Keywords:

Wernicke's encephalopathy; Classical triad; Alcoholism.

Abstract

Among the encephalopathies, some have been more studied in recent decades, such as Wernicke's encephalopathy (WE), which is a set of neuropsychiatric signs and symptoms that result from a nutritional deficiency of thiamine. This research is a systematic bibliographic review, of the quantitative type, which used the platforms PubMed, Scientific Electronic Library Online (SciELO) and Google Scholar as a database for researching scientific articles. Literature published with a time frame from 2016 to 2021, in English, that addressed Wernicke's Encephalopathy and its pathophysiological and clinical aspects were used. Therefore, it was found that the deficiency of thiamine (vitamin B1) is able to lead the patient to develop Wernicke's encephalopathy, when the disease is associated with anterograde amnesia. Furthermore, the underlying condition described in WE is alcoholism. Therefore, high doses of parenteral thiamine in high-risk patients are essential for the patient's gradual improvement.

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Published

19/12/2021

How to Cite

FONSECA, G. S. G. B. .; ASSUNÇÃO, I. L. .; PACHECO, L. O. P. L. .; FREITAS JÚNIOR, W. U. de .; TRINDADE, P. O. .; SODRÉ NETO SEGUNDO, A.; REGO, C. P. A. .; SILVA, J. D. da C. F. da .; AGUIAR, R. C. de .; BORGES, F. de A. .; COELHO, C. N. do N. .; COSTA, A. C. N. .; GARCIA, A. C. R. .; FREIRE, V. M. L. M. .; MARINHO, L. C. O. .; LIMA, P. de L. .; ANDRADE, P. P. .; MAIA, A. V. F. B. .; BONFIM, L. L. .; SILVA, M. C. .; CARVALHO, B. N. .; CARMO, F. S. R. .; SILVA, V. M. da .; ABREU, D. B. .; LEITE, M. J. F. L. .; MACHADO, P. S. .; COSTA, A. B. S. .; GONÇALVES , R. P. Pathophysiological, clinical and treatment repercussions of Wernicke’s Encephalopathy: a review. Research, Society and Development, [S. l.], v. 10, n. 16, p. e580101623857, 2021. DOI: 10.33448/rsd-v10i16.23857. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/23857. Acesso em: 26 dec. 2024.

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Vol. 10 No. 16

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Health Sciences

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Copyright (c) 2021 Gustavo Soares Gomes Barros Fonseca; Izabely Lima Assunção; Luyla Oliveira Paes Landim Pacheco; Wellington Ubaldino de Freitas Júnior; Patrielly Oliveira Trindade; Ademar Sodré Neto Segundo; Cecília Pessoa Almeida Rego; Janyne Daniel da Cunha França da Silva; Rebeca Carvalho de Aguiar; Fernando de Abreu Borges; Claudia Nery do Nascimento Coelho; Ana Clara Nóbrega Costa; Ana Clara Rocha Garcia; Vivianne Maria Laranjeiras Monte Freire; Luana Caroline Oliveira Marinho; Pedro de Lacerda Lima; Pietra Possapp Andrade; Ana Vitória Feitosa Barroso Maia; Lais Lima Bonfim; Mikael Coutinho Silva; Bárbara Nussrala Carvalho; Fernanda Soares Rezende Carmo; Vanessa Marques da Silva; David Brusaca Abreu; Maria Julia Fonseca Lima Leite; Paula Soares Machado; Arthur Brício Silva Costa; Rafael Pavão Gonçalves

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