Health education: Development of educational material for hand-foot syndrome secondary to the use of capecitabine
DOI:
https://doi.org/10.33448/rsd-v10i17.24093Keywords:
Neoplasm; Antineoplastics; Capecitabine; Hand-foot syndrome; Health education.Abstract
Cancer is the main public health problem in the world. Anticancer drugs can have serious adverse reactions, many of which are potentially fatal if not properly managed. Capecitabine is a chemotherapeutic prodrug that is frequently used in the treatment of breast, colon and rectal cancer. Among the most frequent toxicities in patients undergoing capecitabine use is hand-foot syndrome (HFS). The objective this study was to develop a folder of guidelines for the prevention and treatment of HFS aimed at patients who use capecitabine in order to optimize their treatment. This is an experience report that involved three steps: problem identification; narrative literature review, layout development, illustrations and writing in folder format. The material consisted of simple guidelines, demonstrating the main signs and symptoms of HFS, in addition to a telephone number for contacting the service. Questions related to changing lifestyle habits were also included, such as improving water intake, wearing comfortable shoes and the temperature of the bath water, as well as care with the handling of cleaning products. In addition, non-pharmacological methods were mentioned, such as the use of urea-based creams, aloe vera and laser therapy. We concluded that the elaboration of the folder proposed a printed educational material that allowed a more assertive approach, aimed at the individual, clarifying their doubts and ensuring better treatment.
References
Addor F. A. S., & Aoki V. (2010). Barreira cutânea na dermatite atópica. Anais Brasileiros de Dermatologia, 85 (2), 184–94.
Bertella T., Pretto L. C., Pasinato R., Picinin D., Ebel A., Schorn G. D., & Mioso C. (2020). Acompanhamento farmacoterapêutico na dispensação de medicamentos antineoplásicos via oral: relato de experiência. I Simpósio Sul Brasileiro de Oncologia Clínica e Cirúrgica, v 1, n 1.
Bray F., Ferlay J., Soerjomataram I., Siegel R. L., Torre L. A., & Jemal A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68 (6), 394–424.
Chen, Y., Jobanputra, P., Barton, P., Bryan, S., Fry-Smith, A., Harris, G., & Taylor, R. (2008). Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. Health Technology Assessment, 12 (11).
Costa J. S., Silva G. M., Kameo S. Y., Amorim B. F., & Ramos M. J. O. (2019). Síndrome mão-pé induzida por quimioterapia: abordagem clínica e epidemiológica de pacientes com câncer. Rev Bras Cancerol, 65 (2).
Fernandes C. D. L., Castro C.Q., Franciele E., Maria V., & Bayer L. (2019). Vigilância em Saúde: ações de promoção, prevenção, diagnóstico e tratamento. Perfis dos pacientes em tratamento quimioterápico com capecitabina no hospital universitário de Santa Maria/RS. 6º Congresso Internacional em Saúde.
Freitas, K. A. B. S. (2020). Efeitos da fotobiomodulação no extravasamento de antraciclina: estudo experimental. Universidade Estadual Paulista “Júlio de Mesquita Filho”, Faculdade de Medicina de Botucatu.
Freitas, K. A. B. S., Lima, T. O., Minicucci, E. M., Silva, K. A. B., & Vigliassi, A. P. (2020). Association of photobiomodulation and topical hyaluronidase in extravasation and infiltration of antineoplastics. Retrospective stud. Revista Nursing, 23 (271), 4975-4978.
Hekmatpou D., Mehrabi F., Rahzani K., & Aminiyan A. (2019). The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review. Iranian Journal of Medical Sciences, 44 (1), 1–9.
Johnsen S. P. (2005). Risk of Hospitalization for Myocardial Infarction Among Users of Rofecoxib, Celecoxib, and Other NSAIDs. Archives of Internal Medicine, 165 (9), 978.
Júnior W. B., Tomaz A. C. A., Vieira L. F. A., Silva P. M. X., Oliveira S. M. B., & Lima M. K. S. (2017). Capecitabine induced hand-foot syndrome-a case report. Cogitare Enferm, 22 (1), 01-04.
Latifyan S., Genot M. T., Fernez B., Scharll M. F., & Klastersky J. A. (2019). Use of low-level laser therapy (LLLT) or photobiomodulation (PBM) for the management of the hand-foot syndrome (HSF) or palmo-plantar erythrodysesthesia (PPED) associated with cancer therapy. Supportive Care in Cancer, 28 (7), 3287–90.
Li J., & Gu J. (2017). Hand-foot skin reaction with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: A systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 119, 50–8.
Lins R. D. A. U., Dantas E. M., Lucena K. C. R., Catão M. H. C. V., Granville-Garcia A.F., & Carvalho Neto L.G. (2010). Efeitos bioestimulantes do laser de baixa potência no processo de reparo. Anais Brasileiros de Dermatologia, 85 (6), 849–55.
Macedo L. T., Lima J. P., Santos L. V., & Sasse A. D. (2014) Prevention strategies for chemotherapy-induced hand-foot syndrome: a systematic review and meta-analysis of prospective randomized trials. Support Care Cancer. 22 (6), 1585-93.
Martins T. L., Pinto A. R., Pires J. M. D., Silva M. J. S. D., Couto D. H. N., & Elias S.C. (2019). Adverse reaction induced by capecitabine: the importance of pharmacovigilance | Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde. Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde. http://www.rbfhss.org.br/sbrafh/article/view/163
Mathers, C. D., Bernard, C., Iburg, K. M., Inoue, M., Ma Fat, D., Shibuya, K., Stein, C., Tomijima, N., & Xu, H. (2003). Global Burden of Disease in 2002: data sources, methods and results. World Health Organization. 54th ed.
Medina A. M., Leal A. F., Zavaglia G. O., Muniz R. M., Guimarães S. R. L., & Faes A. D. R. (2013). A consulta de enfermagem como estratégia de cuidado ao cliente oncológico em tratamento radioterápico. Ciência, Cuidado e Saúde, 7. https://doi.org/10.4025/cienccuidsaude.v7i0.6727.
Modesto A. C. F., Ferreira T. X. A. M., Provin M. P., Amaral R. G., & Lima D. M. (2016). Reações Adversas a Medicamentos e Farmacovigilância: Conhecimentos e Condutas de Profissionais de Saúde de um Hospital da Rede Sentinela. Revista Brasileira de Educação Médica, 40 (3), 401–10.
National Cancer Institute (US). Division of cancer treatment and diagnosis. Commom toxicity criteria (Computer Program). Version 5.0 NCI; 2017.
Ozkol, H. U., Calka, O., & Bulut, G. (2013). Chemotherapy-induced acral erythema with involvement of the face and neck. Toxicology and Industrial Health, 32 (5), 791–4.
Pereira, P. P., Pedroso, R. S., & Ribeiro, M. A. (2020). Identificação, Prevenção e Tratamento da Síndrome Mão-Pé Induzida por Quimioterapia: Revisão Sistemática. Revista Brasileira de Cancerologia, 65 (4).
Phaniendra, A., Jestadi, D. B., & Periyasamy L. (2014). Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases. Indian Journal of Clinical Biochemistry, 30 (1), 11–26.
Polit, D. F. & Beck, C. T. (2011). Fundamentos de pesquisa em enfermagem: avaliação de evidências para a prática da enfermagem. Porto Alegre: Artmed, 7ª ed.
Rezende, R., & Lenzi, J. (2020). Eletrotermofooterapia em Oncologia: da evidência à prática clínica. 1. ed. Rio de Janeiro: Thieme Revinter Publicações, 312 p.
Richardson, J., Smith J. E., McIntyre M., Thomas, R., & Pilkington, K. (2005). Aloe Vera for Preventing Radiation-induced Skin Reactions: A Systematic Literature Review. Clinical Oncology, 17 (6), 478–84.
Richards, K. N., Ivan, D., Rashid, R. M., & Chon, S. Y. (2012). Paclitaxel-Induced Acral Erythema. Archives of Dermatology, 148 (11), 1333.
Robijns, J., Censabella, S., Claes, S., Pannekoeke, L., Bussé, L., Colson, D., Kaminski, I., Lodewijckx, J., Bulens, P., Maes, A., Noé, L., Brosens, M.,
Sanches O. (2017). Síndrome Mão-Pé: prevenção, diagnóstico e tratamento. [Cartilha]. Instituo Viver Hoje. www.viverhoje.org.
Simão, D. A. S., Lima, E. D. R. P., Souza, R. S., Faria, T. V., & Azevedo, G. F. (2012). Síndrome mão-pé induzida por quimioterapia: relato de um caso. Revista Brasileira de Enfermagem, 65 (2), 374–8.
Thalita, M. (2017). Ureia para prevenção da eritrodisestesia palmo-plantar em pacientes submetidos à quimioterapia: revisão sistemática. https://bdm.unb.br/handle/10483/18411.
Trivelin, M. L. O. A. A., Alchorne, A. O. A., Marques, E. R. M. C., Alchorne, M. M. A., Silva, M. F., Freixadas, E. M. R., Trivelin, S. A. A., & Chavantes, M. C. (2020). Avaliação do efeito clínico da terapia de fotobiomodulação com uso do laser de baixa intensidade em rosácea eritêmato-telangiectásica: Estudo piloto. Brazilian Journal of Development, 6 (7), 50152–50175.
Watkins, A. A., Johnson, T. V., Shrewsberry, A. B., Nourparvar, P., Madni, T., Watkins, C. J., Feingold, P. L., Kooby, D. A., Maithel, S. K., Staley, C. A., & Master, V. A. (2014). Ice Packs Reduce Postoperative Midline Incision Pain and Narcotic Use: A Randomized Controlled Trial. Journal of the American College of Surgeons, 219 (3), 511–517.
Xeloda (capecitabina). [Bula]. Rio de Janeiro: Produtos Roche Químicos e Farmacêuticos S.A; 2020.
Zhang, R. X., Wu, X. J., Wan, D. S., Lu, Z. H., Kong, L. H., Pan, Z. Z., & Chen, G. (2012). Celecoxib can prevent capecitabine-related hand-foot syndrome in stage II and III colorectal cancer patients: result of a single-center, prospective randomized phase III trial. Annals of Oncology, 23(5), 1348–1353.
Zecha, J. A. E. M., Raber-Durlacher, J. E., Nair, R. G., Epstein, J. B., Sonis, S. T., Elad, S., Hamblin, M. R., Barasch, A., Migliorati, C. A., Milstein, D. M. J., Genot, M.-T., Lansaat, L., van der Brink, R., Arnabat-Dominguez, J., van der Molen, L., Jacobi, I., van Diessen, J., de Lange, J., Smeele, L. E., Bensadoun, R.-J. (2016). Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations. Supportive Care in Cancer, 24 (6), 2781–2792.
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Copyright (c) 2021 Fernando Césare Batista Cessel; Talita Oliveira de Lima; Mayara Spin; Tânia dos Santos Salvador; Bruna Santos Ezequiel; Karina Alexandra Batista da Silva Freitas
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