The effect of nutritional formulas used in the treatment of children with cow milk protein allergy: a systematic review
DOI:
https://doi.org/10.33448/rsd-v11i2.25594Keywords:
Milk hypersensitivity; Soy foods; Food hypersensitivity.Abstract
Introduction: The literature has shown an increase in the prevalence of children with allergy to cow's milk protein (APLV) and their treatment consists of this food and its dietary derivatives and its replacement by formulas based on isolated soy protein or formulas hydrolyzed. Objective: To evaluate the effects of using nutritional formulas in children with APLV. Methodology: The search and selection of articles followed the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), using the keywords: “milk hypersensitivity”,” food hypersensitivity, hydrolyzed”, “vegetable protein”, “vegetable protein”, “soy bean proteins” in combination or alone, in Pubmed, Scopus and Science direct databases. Results: Nine articles were included, including six clinical trials, a cohort study, an observational study and a multicenter study. Were tested: extensively hydrolyzed protein formula, amino acid-based formula and soy-based formula. In 3 studies, extensively hydrolyzed protein and amino acid formulas were associated with probiotics Lactobacillus rhamnosus. and there were 2 studies associated with symbiotics. Conclusion: All types of formulas analyzed contributed to improvement in symptoms related to APLV, with the best results observed for formulas with probiotics. However, further studies are needed to assess the effects of added probiotics in nutritional formulas for the treatment of APLV, its potential needs to be better evaluated, especially in long-term studies.
References
Aguiar, A. L. O. (2013). Avaliação clínica e evolutiva de crianças em programa de ate. Rev Paul Pediatr, 31 (2), 152-8. 10.1590/S0103-05822013000200004.
Barros, K.V. et al. (2017). Evidence for Involvement of IL-9 and IL-22 in Cows' Milk Allergy in Infants. Nutrients, 9 (1040), 1-10. 10.3390/nu9101048.
Berni, R. et al. (2015). Differences in DNA methylation profile of Th1and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow's milk allergy. Clin Epigenet. 7 (1), 1-9. 10.1186/s13148-015-0070-8.
Berni, R.et al. (2016). Lactobacillus rhamnosus GG supplemented formula expands butyrate producing bacterial strains in food allergic infants. ISME J.10 (1), 742-750. 10.1038/ismej.2015.151.
Brasil (2008). Associação Brasileira de Alergia e Imunopatologia. Consenso brasileiro sobre alergia alimentar: 2007. Revista Brasileira de Alergia e Imunologia, 31 (2), 64-89.
Brasil (2018). Associação Brasileira de Alergia e Imunopatologia. Consenso brasileiro sobre alergia alimentar: 2007. Arquivos de Asma, Alergia e Imunologia, 2 (1), 39-82.
Boettcher, E. & Crowe, S. E. (2013). Dietary proteins and functional gastrointestinal disorders. Am J Gastroenterol.108 (5), 728-36. 10.1038/ajg.2013.97.
Caetano, M. C., Ortiz, T.T., Silva, S. G. L., Souza F. I. S. & Sarni, R. O. S. (2010). Alimentação complementar: práticas inadequadas em lactentes. J. Pediatr., 86 (3), 196-201. 10.5123/S1679-49742015000300012.
Canani, R.B. et al. (2017). Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow’s milk allergy: 3-year randomized controlled trial. J allergy clin immunol., 139 (6), 1906-1914. 10.1016/j.jaci.2016.10.050.
Candy, D. C. A., et al. (2018). A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants. Pediatr Res., 83 (3), 677-686.10.1038/pr.2017.270.
Dupont, C., Bradatan, E., Soulaine, P., Nocerino, R. & Berni-Canani, R. (2016). Tolerance and growth in children with cow’s milk allergy fed a thickened extensively hydrolyzed casein-based formula. BMC Pediatrics. 16 (96), 1-8. 10.1186/s12887-016-0637-3.
Dupont C., Hol J. & Nieuwenhuis E. E.S. (2015). An extensively hydrolysed casein-based formula for infants with cows’ milk protein allergy: tolerance/hypo-allergenicity and growth catch-up. British Journal of Nutrition.113 (1), 1102–1112. 10.1017/S000711451500015X.
Delgado, A. F., Cardoso, A. L. & Zamberlan, P. (2010). Nutrologia básica e avançada. 1. ed. São Paulo: Manole.
Dupont, C. et al. (2011). Dietary treatment of cows’ milk protein allergy in childhood: a commentary by the Committee on Nutrition of the French Society of Paediatrics. Br J Nutr, 107 (1), 325-338. 10.1017/S0007114511004831.
Eloe-Fadrosh, E. A. et al. (2015). Functional dynamics of the gut microbiome in elderly people during probiotic consumption. MBio,1 (1), 6. 10.1128/mBio.00231-15.
Ferreira, C. T. & Seidman, E. (2007). Alergia alimentar: atualização prática do ponto de vista gastroenterológico. Jornal de Pediatria, 83 (1), 7-20. 10.1590/S0021-75572007000100004.
Fiocchi, A., et al. (2010). World Allergy Organization (WAO) diagnosis and rationale for action against cow’s milk allergy (DRACMA) Guidelines. World Allergy Organ J. 3 (4), 57–161. 10.1097/WOX.0b013e3181defeb9.
Gourbeyre, P., Denery, S.& Bodinier, M. (2011). Probióticos, prebióticos e simbióticos: Impacto no sistema imunológico do intestino e reações alérgicas. J. Leukoc. Biol., 89 (1), 685–695. 10.1590/S0103-05822010000100014.
Harvey, B. M., Eussen, S. R. B. N., Harthoorn, L. F. & Burks, A. W. (2017). Mineral Intake and Status of Cow’s Milk Allergic Infants Consuming an Amino Acid-based Formula. Short communication: nutrition, 65 (3), 346-340. 10.1097/MPG.0000000000001655.
Hill, C. et al. (2014). Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat. Rev Gastroenterol Hepatol, 11 (8), 506-14. 10.1038/nrgastro.2014.66.
Host, A. & Halken, S. (2014). Cow's milk allergy: where have we come from and where are we going? Endocr Metab Immune Disord Drug Targets., 14 (1), 2-8. 10.2174/1871530314666140121142900.
Koletzko, S. et al. (2012). Diagnostic approach and management of cow’s milk protein allergy in infants and children: ESPGHAN GI Committee pratical guidelines. Journal of Pediatric Gastroenterology and Nutrition, 55 (1), 221-229. 10.1097/MPG.0b013e31825c9482.
Kemp, A. S., et al. (2008). Guidelines for the use of infant formulas to treat cows milk protein allergy: an Australian consensus panel opinion. Med J Aust.188,109-12. 10.5694/j.1326-5377.2008.tb01534.x.
Lebeer S. et al. (2012). Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells. Appl Environ Microbiol.78 (1), 185–193. 10.1128/AEM.06192-11.
London (2002). Milton Keynes Primary Care Trust. Critical Appraisal Skills Programme. London: Oxford.
Manuyakorn, W. & Tanpowpong, P. (2019). Cow milk protein allergy and other common food allergies and intolerances. Paediatr Int Child Health., 39 (1), 32-40. 10.1080/20469047.2018.1490099.
Mcbride, D. et al., (2012). The EuroPrevall birth cohort study on food allergy: baseline characteristics of 12,000 newborns and their families from nine European countries, Pediatr Allergy Immunol.,23(1), 230-239. 10.1111/j.1399-3038.2011.01254.x.
Paparo, L., et al., (2016). Epigenetic features of FoxP3 in children with cow's milk allergy. Clin Epigenetics.8 (86), 1-8. 10.1186/s13148-016-0252-z.
Petschow, B.W. et al., (2015). Effects of feeding an infant formula containing Lactobacillus GG on the colonization of the intestine: a dose-response study in healthy infants. J Clin Gastroenterol., 39 (1), 86–790, 10.1097/01.mcg.0000177245.53753.86.
Pereira, P. B. & Silva, C. P. (2008). Alergia a proteína do leite de vaca em crianças: repercussões da dieta de exclusão e da dieta substitutiva sobre o estado nutricional. Revista Pediatria, 30 (2), 100-106.
Reche, M. et al., (2010). O efeito de uma fórmula parcialmente hidrolisada à base de proteína de arroz no tratamento de bebês com alergia à proteína do leite de vaca. Pediatr Allergy Immunol. 21(4), 577-85.
Rioux, K.P. et al. (2005). O papel da microflora entérica na doença inflamatória do intestino: Estudos em humanos e animais com probióticos e prebióticos. Gastroenterol. Clin. N. Am., 34 (1), 465–482.
Skripak, J.M. et al. (2007). The natural history of IgE-mediated cow's milk allergy. J Allergy Clin Immunol., 1 (1), 120. 10.1016/j.jaci.2007.08.023.
Savage, J. & Johns, C. B. (2014). Food allergy: epidemiology and natural history. Immunol. Allergy Clin. North Am., 35 (1), 45–59.
1016/j.iac.2014.09.004.
Scalabrin, D., Harris, C., Johnston, W.H. & Berseth, C. L. (2017). Long-term safety assessment in children who received hydrolyzed protein formulas with Lactobacillus rhamnosus GG: a 5-year follow-up. Eur J Pediatr., 176 (2), 217-224. 10.1007/s00431-016-2825-4.
Vandenplas, Y. et al. (2007). Guidelines for the diagnosis and management of cow’s milk protein allergy in infants. Arch Dis Child. 92, 902-908, 10.1136/adc.2006.110999.
Vandenplas, Y., De Greef, E. & Hauser, B. (2014). Safety and tolerance of a new extensively hydrolyzed rice protein-based formula in the management of infants with cow’s milk protein allergy. Eur J Pediatr.173 (1),1209–1216. 10.1007/s00431-014-2308-4.
Vandenplas Y. et al. (2015). Extensive protein hydrolysate formula effectively reduces regurgitation in infants with positive and negative challenge tests for cow's milk allergy. Acta Paediatr.104, 449–457. 10.1111/apa.12615.
Venter, C., & Arshad, S. H.(2011). Epidemiology of food allergy. Pediatr. Clin. N. Am., 58 (1), 327–349. /10.1016/j.pcl.2011.02.011.
Yonamine, G. H. et al., (2011). Uso de fórmulas à base de soja na alergia à proteína do leite de vaca. Revista Brasileira de Alergia e Imunopa, 34 (5),187-192.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Rayane Carvalho de Moura; Crislane de Moura Costa; Marilene Magalhães de Brito; Marcos Antônio Pereira dos Santos; Amanda de Castro Amorim Serpa Brandão; Betânia de Jesus e Silva de Almendra Freitas; Adriana de Azevedo Paiva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
