The use of cannabinoids in dermatological pathophysiologies: a systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i2.25961

Keywords:

Cannabis; Cannabinoids; Skin diseases.

Abstract

This article is a systematic bibliographic review carried out in the period from October 25 to November 4, 2021 through electronic search in the databases of Google Scholar, Science Direct and PUBMED-NCBI-NIH to obtain more recent data, the guiding question of the research was: What is the importance of cannabinoids for the treatment of dermatological physiopathology? The eligibility criteria were selected articles from the last three years concerning cannabis, its cannabinoids and the treatment of dermatological lesions. The descriptors used were: Cannabis, Skin diseases and Cannabinoids verified in Health Science Descriptors (Decs) and Medical Subjec the adings (Mesh). The cross was succeeded using the boolean operator AND: "Cannabis" AND "Skindiseases" AND "Cannabinoids". Nine articles were elected, both analyzed qualitatively, through methodological reading. Even though medicinal herb is known for its psychological use, recent studies show that cannabinoids (Cbs) are actively involved in peripheral systems such as the innate, adaptive immune response. The endocannabinoid system is responsible for regulating several aspects of skin homeostasis such as proliferation, release and differentiation of inflammatory mediators. Therefore, it was possible to observe through the research that Cannabis sativa and its system present in the organism, has large participations for the control of several dermatological and non-dermatological diseases, however, studies are still quite recent and scarce regarding the effect of the herb in the dermatological area, however, already has great advances on its effectiveness.

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Published

05/02/2022

How to Cite

SOARES , M. G. da S. .; SILVA, M. E. W. de B.; BARBOSA, M. L. C. da S. .; MACÊDO, L. P. de .; SANTOS JÚNIOR , F. J. S. .; COSTA, A. C. A. .; MACÊDO, A. H. S. de .; FREITAS, Àlex E. D. L. de .; PEIXOTO , G. F. .; CORREIA, V. L. de S. .; MANZINI, A. P. M. .; ONÓRIO, M. E. de L. .; LOPES, R. de C. R. .; PEDREIRA, Y. L.; SOARES , L. L. . The use of cannabinoids in dermatological pathophysiologies: a systematic review . Research, Society and Development, [S. l.], v. 11, n. 2, p. e55411225961, 2022. DOI: 10.33448/rsd-v11i2.25961. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/25961. Acesso em: 22 nov. 2024.

Issue

Vol. 11 No. 2

Section

Health Sciences

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Copyright (c) 2022 Maria Gabryelle da Silva Soares ; Maria Eduarda Wanderley de Barros Silva; Maria Letícia Cardoso da Silva Barbosa; Lindinês Pereira de Macêdo; Francisco Jacinto Silva Santos Júnior ; Allan César Avelino Costa; Alexandre Henrique Silva de Macêdo; Àlex Espinalt Daví Lima de Freitas; Gabriel Fragoso Peixoto ; Vitória Liz de Souza Correia; Ana Paula Moura Manzini; Maria Eduarda de Lima Onório; Rita de Cássia Rodrigues Lopes; Yngrid Lima Pedreira; Larissa Lima Soares

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