Breast angiosarcoma: case report
DOI:
https://doi.org/10.33448/rsd-v9i3.2654Keywords:
Breast câncer; Neoplasms; Sarcomas.Abstract
Primary breast sarcomas are neoplasms originating from the connective tissue of this region and correspond to less than 1% of all mammary malignancies. Primary angiosarcoma of the breast is extremely rare. The relative incidence in relation to breast sarcomas is 2.7 to 7.9%. The predominant clinical aspect is that of a painless breast mass, sometimes with diffuse breast enlargement. The overlying skin may be violet or black in color. It is classified into 3 categories, being: group I or well differentiated. Group II tumors, either intermediate or moderately differentiated - have more frequent mitotic activity; Finally, in group III or poorly differentiated are tumors that present areas of solid growth composed of spindle cells, with pronounced mitotic activity. The aim of this study was to demonstrate a case of breast angiosarcoma in a patient from a public hospital in Teresina – PI.Considering the rare incidence and delayed diagnosis described in the literature that interfere with the early initiation of adequate therapy, here is a case report occurred in our service.
References
Bezerra, A.L.R.; Bezerra, M.C.M.; Albuquerque, L.P.C.M.; Aguiar, L.S,M.P. & Peixoto, J. (2016). Avaliação clínico-epidemiológica de pacientes portadoras de sarcoma de mama na cidade do Recife.
Rev. Bras. Mastologia, 26(3):89:94.
Boff, R.A.; Wisintainer, F. & Amorim, G. (2008). Manual de diagnóstico e terapêutica em mastologia. 2.ed. Caxias do Sul: Mesa Redonda; p. 219-20.
Bordoni, D.; Bolleta, E.; Falco, G. Primary angiosrcoma of the breast. Int J Surg Case Rep. 2016;20(Suppl):12–15. doi: 10.1016/j.ijscr.2016.02.003.
Bousquet, G.; Confavreux, C.; Magne, N.; De Lara, C.T.(2007). Poortmans P., Senkus E. Outcome and prognostic factors in breast sarcoma: a multicenter study from the rare cancer network. Radiother. Oncol.85:355–361.
Donnell, R.M.; Rosen, P.P.; Lieberman, P. H.; Kaufman, R.J.; Braun, D.W.; Kinne, D.W. (1981). Angiosarcoma and other vascular tumours of the breast. Am J Surg Pathol. 5(7):629–42.
Karlsson, P.; Holmberg, E.; Samuelsson, A.; Johansson, K.A.; Wallgren, A. (1998). Soft tissue sarcoma after treatment for breast cancer – a Swedish population-based study. Eur J Cancer.;34(13):2068-75.
Kiluk, J.V.; Yeh, K.A.(2005). Primary angiosarcoma of the breast. Breast J. 11:517-8.
Merino, M.J.; Carter. D.; Berman, M.(1983). Angiosarcoma of the breast. Am J Surg Pathol. ;7(1):53–60.
Muzumber, S.; Das, P.; Kumar, M. (2010). Primary epithelioid angiosarcoma of the breast masquerading as carcinoma. Curr Oncol. 17(1):64–69.
Pirozzi, P.R.; Rossetti, C.; Carelli Filho, I.; Pozzan, G.; Rinaldi, J.F.; Oliveira, V.M.; Piato, S. (2007) Angiossarcoma mamário após cirurgia conservadora do câncer de mama seguido de radioterapia: relato de caso. Arq Med Hosp Fac Cienc Med Santa Casa São Paulo. 52(3):117-21.
Rosen, P.P.; Kimel, M.; Ernsberger, D. (1988) Mammary angiosarcoma. The prognostic significance of tumor differentiation. Cancer. 62:2145–2151.
Scow, J.S.; Reynolds, C.A.; Deggnim, A.C.; Peterson, I.A., Jakub, J.W.; Bonghoy, J.C.(2010) Primary angiosarcoma of the breast: the Mayo Clinic experience. Journal of Surgical Oncology. 101(5):401–07.
Shabahang, M.; Franceschid, D.; Sundaram, M.; Castilho, M.H.; Moffat, F.L.; Franks, D.S.(2002) Surgical management of primary breast sarcoma. Am Surg.;68(8);673-7.
Sher, T.; Hennessy, B.T.; Valero, V.; Broglio, K.; Woodward, W.A.; Trent, J.(2007) Primary angiosarcomas of the breast. Cancer. 110(1):173-8.
Silva, H. R.; Costa, R. H. F.; Pinheiro Neto, J. C.; Macedo Junior, C. A. A.; Pacheco, N.I.; Pessoa, G. T. (2020) Associação prevalência e fatores de risco entre obesidade e cancer de mama. Research, Society and Development, v. 9, n. 3
Smoll, N.R.; Farhadieh, R.D.; Ferguson, R.; Findlay, M.W.; Hunter-Smith, D.J. (2013) High-grade Angiosarcoma Associated with Ruptured Breast Implants. Plast Reconstr Surg Glob Open. ;1(1)
Viviani, R.S.O.; Gebrim, L.H.; Nazario, A.C.P.; Kemp, C.; Lima, G.R. (2000) Angiossarcoma de mama – relato de caso. Rev Bras Ginecol Obstet. 22(7):455-8.
Wang, J.; Fisher, C.; Thway, K. (2013). Angiosarcoma of the breast with solitary metastasis to the ovary during pregnancy: an uncommon pattern of metastatic disease. Case Rep Oncol Med.
Yang, W.T.; Hennessy, B.T.; Dryden, M.J.; Valero, V.; Hunt, K.K.; Kri-Shnamurthy, S. (2007) Mammary angiosarcomas: imaging findings in 24 patients. Radiology. 242(3):725–34.
Young, R. J.; Brown, N. J.; Reed, M. W.; Hughes, D.; Woll, P. J. (2010) Angiosarcoma. The Lancet Oncology. 11(10):983–991. doi: 10.1016/S1470-2045(10)70023-1.
Zelek, L.; Llobart-Cussac, A.; Terrier, P.; Pivot, X.; Guinebretiere, J.M.; Le Pechoux, C. (2003) Pronostic factors in primary breast sarcomas: a series of patient with long-term follow-up. J Clin Oncol.21(13):2583–8.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Mikaela Lopes de Caldas, Lucas Almeida Medeiros, Júlio César Saraiva Santos, Anna Catharina Feitosa Costa, Simone Madeira Nunes Miranda
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.