Breast angiosarcoma: case report

Authors

DOI:

https://doi.org/10.33448/rsd-v9i3.2654

Keywords:

Breast câncer; Neoplasms; Sarcomas.

Abstract

Primary breast sarcomas are neoplasms originating from the connective tissue of this region and correspond to less than 1% of all mammary malignancies. Primary angiosarcoma of the breast is extremely rare. The relative incidence in relation to breast sarcomas is 2.7 to 7.9%. The predominant clinical aspect is that of a painless breast mass, sometimes with diffuse breast enlargement. The overlying skin may be violet or black in color. It is classified into 3 categories, being: group I or well differentiated. Group II tumors, either intermediate or moderately differentiated - have more frequent mitotic activity; Finally, in group III or poorly differentiated are tumors that present areas of solid growth composed of spindle cells, with pronounced mitotic activity. The aim of this study was to demonstrate a case of breast angiosarcoma in a patient from a public hospital in Teresina – PI.Considering the rare incidence and delayed diagnosis described in the literature that interfere with the early initiation of adequate therapy, here is a case report occurred in our service.

References

Bezerra, A.L.R.; Bezerra, M.C.M.; Albuquerque, L.P.C.M.; Aguiar, L.S,M.P. & Peixoto, J. (2016). Avaliação clínico-epidemiológica de pacientes portadoras de sarcoma de mama na cidade do Recife.

Rev. Bras. Mastologia, 26(3):89:94.

Boff, R.A.; Wisintainer, F. & Amorim, G. (2008). Manual de diagnóstico e terapêutica em mastologia. 2.ed. Caxias do Sul: Mesa Redonda; p. 219-20.

Bordoni, D.; Bolleta, E.; Falco, G. Primary angiosrcoma of the breast. Int J Surg Case Rep. 2016;20(Suppl):12–15. doi: 10.1016/j.ijscr.2016.02.003.

Bousquet, G.; Confavreux, C.; Magne, N.; De Lara, C.T.(2007). Poortmans P., Senkus E. Outcome and prognostic factors in breast sarcoma: a multicenter study from the rare cancer network. Radiother. Oncol.85:355–361.

Donnell, R.M.; Rosen, P.P.; Lieberman, P. H.; Kaufman, R.J.; Braun, D.W.; Kinne, D.W. (1981). Angiosarcoma and other vascular tumours of the breast. Am J Surg Pathol. 5(7):629–42.

Karlsson, P.; Holmberg, E.; Samuelsson, A.; Johansson, K.A.; Wallgren, A. (1998). Soft tissue sarcoma after treatment for breast cancer – a Swedish population-based study. Eur J Cancer.;34(13):2068-75.

Kiluk, J.V.; Yeh, K.A.(2005). Primary angiosarcoma of the breast. Breast J. 11:517-8.

Merino, M.J.; Carter. D.; Berman, M.(1983). Angiosarcoma of the breast. Am J Surg Pathol. ;7(1):53–60.

Muzumber, S.; Das, P.; Kumar, M. (2010). Primary epithelioid angiosarcoma of the breast masquerading as carcinoma. Curr Oncol. 17(1):64–69.

Pirozzi, P.R.; Rossetti, C.; Carelli Filho, I.; Pozzan, G.; Rinaldi, J.F.; Oliveira, V.M.; Piato, S. (2007) Angiossarcoma mamário após cirurgia conservadora do câncer de mama seguido de radioterapia: relato de caso. Arq Med Hosp Fac Cienc Med Santa Casa São Paulo. 52(3):117-21.

Rosen, P.P.; Kimel, M.; Ernsberger, D. (1988) Mammary angiosarcoma. The prognostic significance of tumor differentiation. Cancer. 62:2145–2151.

Scow, J.S.; Reynolds, C.A.; Deggnim, A.C.; Peterson, I.A., Jakub, J.W.; Bonghoy, J.C.(2010) Primary angiosarcoma of the breast: the Mayo Clinic experience. Journal of Surgical Oncology. 101(5):401–07.

Shabahang, M.; Franceschid, D.; Sundaram, M.; Castilho, M.H.; Moffat, F.L.; Franks, D.S.(2002) Surgical management of primary breast sarcoma. Am Surg.;68(8);673-7.

Sher, T.; Hennessy, B.T.; Valero, V.; Broglio, K.; Woodward, W.A.; Trent, J.(2007) Primary angiosarcomas of the breast. Cancer. 110(1):173-8.

Silva, H. R.; Costa, R. H. F.; Pinheiro Neto, J. C.; Macedo Junior, C. A. A.; Pacheco, N.I.; Pessoa, G. T. (2020) Associação prevalência e fatores de risco entre obesidade e cancer de mama. Research, Society and Development, v. 9, n. 3

Smoll, N.R.; Farhadieh, R.D.; Ferguson, R.; Findlay, M.W.; Hunter-Smith, D.J. (2013) High-grade Angiosarcoma Associated with Ruptured Breast Implants. Plast Reconstr Surg Glob Open. ;1(1)

Viviani, R.S.O.; Gebrim, L.H.; Nazario, A.C.P.; Kemp, C.; Lima, G.R. (2000) Angiossarcoma de mama – relato de caso. Rev Bras Ginecol Obstet. 22(7):455-8.

Wang, J.; Fisher, C.; Thway, K. (2013). Angiosarcoma of the breast with solitary metastasis to the ovary during pregnancy: an uncommon pattern of metastatic disease. Case Rep Oncol Med.

Yang, W.T.; Hennessy, B.T.; Dryden, M.J.; Valero, V.; Hunt, K.K.; Kri-Shnamurthy, S. (2007) Mammary angiosarcomas: imaging findings in 24 patients. Radiology. 242(3):725–34.

Young, R. J.; Brown, N. J.; Reed, M. W.; Hughes, D.; Woll, P. J. (2010) Angiosarcoma. The Lancet Oncology. 11(10):983–991. doi: 10.1016/S1470-2045(10)70023-1.

Zelek, L.; Llobart-Cussac, A.; Terrier, P.; Pivot, X.; Guinebretiere, J.M.; Le Pechoux, C. (2003) Pronostic factors in primary breast sarcomas: a series of patient with long-term follow-up. J Clin Oncol.21(13):2583–8.

Published

09/03/2020

How to Cite

CALDAS, M. L. de; MEDEIROS, L. A.; SANTOS, J. C. S.; GOMES, C.; COUTO, A. C. F.; MIRANDA, S. M. N. Breast angiosarcoma: case report. Research, Society and Development, [S. l.], v. 9, n. 3, p. e179932654, 2020. DOI: 10.33448/rsd-v9i3.2654. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/2654. Acesso em: 21 nov. 2024.

Issue

Section

Health Sciences