Preliminary phytochemical analysis of the ethanolic extract of Xerophyta stenophylla Baker
DOI:
https://doi.org/10.33448/rsd-v11i5.28319Keywords:
Schistosomiasis; Xerophyta stenophylla Baker; Muxima; Pharmacological.Abstract
The species Xerophyta stenophyla Baker of the family Velloziaceae is known in Angola as “Chá do Iona” by the people of the Muxima region, Luanda. This species is alternatively used for alleviating schistosomiasis symptoms. The information available in the literature on “Chá do Iona” is scarce. Thus, we investigated the leaf and stem extracts' preliminary phytochemical and biological screening to assess their antioxidant potential. The phytochemical profile was determined in hydroethanolic extract (5:95). The extract yield for this plant species was 0.26%, and there was a positive presence of flavonoids, coumarins, anthraquinones, tannins, saponins, and alkaloids and a negative presence of anthocyanins. Fifteen substances were identified by gas chromatography coupled with mass spectrometry, among which cineole <1,8> and mentha-1 (7), 8-dien-2-ol <trans-ρ-> showed areas of 19, 31% and 17.59%, respectively. The tests for antioxidant activity confirmed the antioxidant potential of this plant. These preliminary results indicate that Xerophyta stenophylla Baker has promising pharmacological potential and can be officially included in the Angolan pharmacopeia.
References
Adams R. P. Identification of essential oil components by gas chromatography/mass spectrometry. (4th ed.), Carol Stream: Allured Publishing. 2007.
Astani, A., Reichling, J., & Schnitzler, P. (2011). Screening for Antiviral Activities of Isolated compounds from Essential Oils. Evidence-Based Complementary and Alternative Medicine, 12(6), 283-28.
Araújo, C. A. C., & Leon L. L. Biological activities of Curcuma longa L. (2001). Memories of the Oswaldo Cruz Institute, 96, 723-728.
Araújo, T. A. S., Melo, J. G., & Albuquerque, U. P. (2014). Medicinal plants. In: Albuquerque, U.P. (org.) Introduction to ethnobiology. Recife: NUPEEA. 91-98.
Bahia. (2019). Health Secretariat of the State of Bahia. Schistosomiasis. Available at: http://www.saude.ba.gov.br/suvisa/vigilancia-epidemiologica/doencas-detransmissao-vetorial/esquistossomose. Accessed on: 23 septs.
Bragagnollo, G. R., Godoy, P. C. G. de T., Santos, T. S., Ribeiro, V.dos. S. Moreno, J. A. P., & Ferreira, B. R. (2018). Educational intervention on enteroparasitosis: a quasi-experimental study, Revista Cuidarte, 9 (2030-2044).
Bossard, E. (1996). La Medicine Traditionnelle au centre et a L’Ouest de L’Angola. Lisboa, Instituto de Investigação Científica Tropical.
Carvalho, O. S. (2018). Geographical distribution of Schistosoma mansoni intermediate hosts in the states of Paraná, Minas Gerais, Bahia, Pernambuco and Rio Grande do Norte, 2012-2014. Epidemiology and Health Services, 27(3).
Cimenman, B. (2011). Atlas of Human Parasitology. (2nd ed.), Editora, Atheneu.
Chan, R.; Brooks, R., Erlich, J., Gallagher, M., Snelling, P., Chow, J., & Suranyi, M. (2011). Studying psychosocial adaptation to endstage renal disease: The proximal-distal model of health-related outcomes as a base model. Journal of Psychosomatic Research, 70(5):455-464. http://dx.doi.org/10.1016/j.jpsychores.2010.11.005.
De Sousa, N. F. (2021). Recent Studies on Neglected Drug Design. Current topics in medicinal chemistry, 21(21), 1943-1974.
Grácio M. (1977). Incidência da Bilharziose Vesical em escolas do distrito de Luanda (Área de Bom Jesus). An. Inst. Med. Trip.; 5: 171-175.
Gautam, I. N., Ling, T. W., & Rivas, F. (2016). Anti-proliferative Evaluation of Monoterpene Derivative against Leukemia. European Journal of Medicinal Chemistry. In Press. Accepted Manuscript. Available online.
Grimes, J. E. (2015) The roles of water, sanitation and hygiene in reducing schistosomiasis: a review. Parasit Vectors, 8, 156.
Hotez, P. J., & Fenwick, A (2009). Schistosomiasis in África: An Emerging Tragedy in Our New Global Health Decade. PLos Neglected Tropical Disease, 3(9): e 485.
Isaac, I. Bogoch, J. T., Coulibaly, J. R., Andrews, B. S., Jennifer K. J., Russell, S., Eliézer, K. N’ & Jürg, U. (2014). Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection.
Kappes, C. (2011) Uses and benefits of Crotalaria in agriculture. Panorama Rural Magazine, Ribeirão Preto, 147: 16-17.
Kweka, E. J., Lima, T. C., Marciale, C. M., & Sousa, D. P. (2016). Larvicidal efficacy of monoterpenes against the larvae of Anopheles gambiae. Asian Pacific Journal of Tropical Biomedicine.
Maghema, T. N. M. (2005) Signs, Meanings and Actions associated with hematobic schistosomiasis. Rachou/Laboratory of Epidemiology and Medical Anthropology.
Da Silva, L, Juliana C. F; & Galvão, G. G. (2021) Integrative and complementary practices in the scope of sus: use, limits and potential. Recima21-Multidisciplinary Scientific Journal, 1(1), e210864-e210864.
Matos, F. J. A. (1997). Introduction to experimental phytochemistry. (2a ed.), Ufc editions. 141.
Mello-Silva, R. (2018). Flora of the cangas of Serra dos Carajás, Pará, Brazil: Velloziaceae. Rodriguésia, 69(1), 259-262.
Mello-Silva, R., Santos, D. Y. A. C., Salatino, M. L. F., Motta, L. B., Cattai, M. B., Sasaki, D., Lovo, J., Pita, P. B., Rocini, C., Rodrigues, C. D. N., Zarrei, M., & Chase, M. W. (2011.). Five vicarious genera from Gondwana: the 281 Velloziaceae as shown by molecules and morphology. Annals of Botany, 108, 87– 102.
Mello, A. G. S., Irmão, J. J. M., Jeraldo V. L. S., & Mello C. M. (2019). Schistosomiasis mansoni in families of fishermen in an endemic area of Alagoas. Anna Nery School. 23 (1).
Ministry of Health-Angola, Secretariat of Health Surveillance. (2010). Department of Epidemiological Surveillance. (2a ed.), Publisher of the Ministry of Health.
Nora, C. D., Muller, C. D., Bona, G. S., Rios, A. O., Hertz, P. F., Jablonski, A., Jong, E. V., & Flôres, S. H. (2014). Effect of processing on the stability of bioactive compounds from red guava (Psidium cattleyanum Sabine) and guabiju (Myrcianthes pungens). Journal of Food Composition and Analysis, v. 34, p.18-25.
Porder, S. (2019). How plants enhance weathering and how weathering is important to plants. Elements, 15, 241– 246. https://doi.org/10.2138/gselements.15.4.241.
Silva, E. A. J., Estevam, E. B. B., Silva, T. S., Nicolella, H. D., Furtado, R. A., Alves, C. C. F., Souchie, E. L., Martins, C. H. G., Tavares, D. C., Barbosa, L. C. A., & Miranda, M. L. D. (2019). Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae). Brazilian Journal of Biology, 79(4), 697-702.
Silva, C. G., Santos Junior, H. M., Barbosa, J. P., Costa, G. L., Rodrigues, F. A. R., Oliveira, D. F., Moraes, M. O., Costa-Lotufo, L. V., Alves, R. J. V., Eleutherio, E. C. A., & Pessoa, C. O. (2015). Structure Elucidation, Antimicrobial and Cytotoxic Activities of a Halimane Isolated from Vellozia kolbekii Alves (Velloziaceae). Chemistry & Biodiversity, 12(12), 1891-1901.
Seca, A. M. L., & Pinto, D. C. G. A. (2018). Plant Secondary Metabolites as Anticancer Agents: Sucesses in Clinical Trials and Therapeutic Application.International Journal of Molecular Sciences, 19, 1- 22.
Siza, J. E., Kaatano, G. M., Chai, J. Y., Eom, K. S., Rim, H. J., Yong, T. S., Min, D. Y., Chang.S. Y., Ko. Y., & Changalucha, J. M. (2015). Prevalence of schistosomes and helminths transmitted by soil and morbidity associated with schistosomiasis among the adult population in the Lake Victoria basin, Tanzania. Korean J Parasitol. 53 (5): 525–533.
Tibiriça, S. H. C., Guimarães, F. B., & Teixeira, M. T. (2011). Schistosoma mansoni in the context of the Brazilian health policy. Ciênc Saúde Coletiva. 16(1): 1375-1381.
Iara, L. M., Samisia, M. F. M., Adauto, R. S., Emmanoel, V. C., Angelita, N., Anderson, B., & Pérola, B. A. (2015). Constitutive of essential oil and hinolate of compomanesia viatoris Landrum leaves. 38(10).
Valeriano, A. C. F. R. (2017). The use of phytotherapy in medicine by SUS users, a systematic review. Multidisciplinary and Psychology Journal, 10(33), 219-236.
Vasconcelos, A. G., Amorim, A. G. N., Santos, R. C., Souza, J. M. T., Souza, L. K. M., Araújo, T. S. L., Nicolau, L.A. D., Carvalho, L.L., Aquino, P. E. A., Martins, C. S., Ropke, C. D.; Soares, P. M. G.; Kuckelhaus, S. A. S.; Medeiros, J. R.; & Leite, J. R. S. A. (2017). Lycopene rich extract from red guava (Psidium guajava L.) displays anti-inflammatory and antioxidant profile by reducing suggestive hallmarks of acute inflammatory response in mice. Food Research International, p. 1-10.
Zhang, Y., Macarthur, C., Mubila, L, & Baker S. (2010). Control of neglected tropical diseases needs a long-term commitment.BMC Medicine. http://www.biomedcentral.com/1741-7015/8/67.
WHO, accelerating work to overcome the global impact of neglected tropical diseases: a roadmap for implementation. (2012). World Health Organization, Geneva.
Lima, L. C. P. (2014). Taxonomic Revision of Desmodium (Leguminosae, Papilionoideae) in Brazil. Phytotaxa, 169(1), 001–119.
Luiza, C. M., & Elder, A. S. P. (2016). Flammable resin in Vellozia variabilis (Velloziaceae).
Renato, M. S. (2018). Flora of the canga of Serra dos Carajás, Pará, Brazil: Velloziaceae. University of São Paulo, Depto. Botany.
Simões, C. M. O., SchenkeL, E. P., Gosmann, G.; MEllo, J. C. P.; Mentz, L. A.; & Petrovick, P. R. (2010). Pharmacognosia: From the plant to the medicine. 6th ed. Porto Alegre/Florianópolis: University/Federal University of Rio Grande do Sul/Federal University of Santa Catarina, p.1102.
Ohashi, H. Tribo Desmodieae. In: Lewis, G. B., Schrire, B., Mackinder, B., & Lock, M. (Ed). (2018). Legumes of the World. Royal Botanic Gardens, Richmond. 433–453, 20.
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Copyright (c) 2022 Dionísio Joaquim da Costa; Anabela Leitão; Robson Xavier Faria; Maria Carolina Anholeti; Maria Antónia Nunes; Maria Beatriz P P Oliveira; Wilson da Costa Santos; Thelma de Barros Machado
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