Integrative review on olfactory disfunctions caused by COVID-19

Authors

DOI:

https://doi.org/10.33448/rsd-v11i5.28384

Keywords:

SARS-CoV-2; Severe acute respiratory syndrome; Olfactory dysfunction; Hypogeusia; Teaching.

Abstract

The study aims to gather and synthesize scientific information related to olfactory dysfunctions caused by SARS-CoV-2 (COVID-19). This is an integrative literature review carried out from scientific journals published from August to December 2021. Original articles with systematic literature reviews, retrospective observational studies, prospective descriptive studies, case-control studies and meta-studies were included meta-analyses. It was concluded that symptoms related to olfactory dysfunctions caused by COVID-19 vary according to age, sex, genetics, stage of the disease and pre-existing comorbidities. The mechanism of action by the virus to promote sensory changes is still uncertain. The main evidence suggests viral dissemination through the olfactory cleft neuroepithelium, with consequent infiltration in the olfactory bulb or neural loss mechanism, with direct damage to the olfactory sensory neurons. Given the complexity of the infection caused by COVID-19 it is essential to continue thematic research, especially in relation to the new variants of SARS-CoV-2.

Author Biographies

Daniela Vieira Buchaim, Universidade de Marília

Possui Graduação em Odontologia pela Universidade de Marília - UNIMAR (1998), Especialização em Ortodontia pela Universidade de Maringá (Uningá ,2011), Mestrado em Biologia Oral pela Universidade do Sagrado Coração (USC,2005), Doutorado em Ciências obtido no programa Ciências Odontológicas Aplicadas (AC: Biologia Oral) na Universidade de São Paulo (Faculdade de Odontologia de Bauru - FOB/USP, 2014) e Pós-Doutorado na Universidade de São Paulo (Faculdade de Odontologia de Bauru - FOB/USP). É professora permanente do Programa de Mestrado Acadêmico em Interações Estruturais e Funcionais na Reabilitação da UNIMAR, na linha de Pesquisa em Reparação Tecidual. É coordenadora de Ensino e Pesquisa do curdo de Medicina e atua Professora Doutora do Centro Universitário de Adamantina (UNIFAI) desde 02/2017 nas disciplinas de Neuroanatomia Humana (Medicina) e Anatomia II (Medicina). É Presidente Docente Supervisora da Liga Acadêmica de Anatomia Clínica e Cirúrgica da UNIMAR e da Liga Acadêmica de Morfofisiologia da UniFAI. Foi coordenadora e ministradora de Cursos de Extensão em Anatomia Topográfica . Tem experiência na área de Morfologia, com ênfase em Anatomia e Morfofisiologia Humana, atuando principalmente nos seguintes temas: Ciências Básicas (Disciplinas básicas da área da Saúde) e pesquisadora nas áreas de Regeneração tecidual e terapia por Fotobiomodulação.

Maria Eduarda Guelfi Pinto, Universidade de Marília

Estudante do 4o ano de Medicina.

Natália Lopes Silva, Universidade de Marília

Estudante do 4o ano de Medicina.

Tarek Mustafa Oliveira, Universidade de Marília

Estudante 4o ano de Medicina.

Otávio Simões Girotto, Universidade de Marília

Estudante 4o ano de Medicina.

Yuuki Daniel Tahara Vilas Boas, Universidade de Marília

Estudante do 4o ano de Medicina.

Gabrielle Gomides Marconato, Universidade de Marília

Estudante do 4o ano de Medicina.

João Victor Pereira Rocha, Universidade de Marília

Estudante do 4o ano de Medicina.

Lucas Ryuiti Adati, Universidade de Marília

Estudante do 4o ano de Medicina.

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Published

12/04/2022

How to Cite

BUCHAIM, D. V.; FURLANETO, L. B.; PINTO, M. E. G.; SILVA, N. L.; OLIVEIRA, T. M.; GIROTTO, O. S.; BOAS, Y. D. T. V.; MARCONATO, G. G.; ROCHA, J. V. P.; ADATI, L. R. Integrative review on olfactory disfunctions caused by COVID-19. Research, Society and Development, [S. l.], v. 11, n. 5, p. e45911528384, 2022. DOI: 10.33448/rsd-v11i5.28384. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/28384. Acesso em: 5 nov. 2024.

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Vol. 11 No. 5

Section

Health Sciences

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Copyright (c) 2022 Daniela Vieira Buchaim; Laura Badiz Furlaneto; Maria Eduarda Guelfi Pinto; Natália Lopes Silva; Tarek Mustafa Oliveira; Otávio Simões Girotto; Yuuki Daniel Tahara Vilas Boas; Gabrielle Gomides Marconato; João Victor Pereira Rocha; Lucas Ryuiti Adati

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