Overview of intoxications associated with the use of medicines registered in Brazil
DOI:
https://doi.org/10.33448/rsd-v9i4.2993Keywords:
Exogenous Intoxication; Use of Medicines; Epidemiology.Abstract
Exogenous intoxication is characterized by the interaction of chemical substances with the living organism. Annually 1.5 to 3% of the population is intoxicated making the disease a public / collective health issue. Quantify and analyze reported cases of drug poisoning in Brazil. This was a documentary, retrospective, descriptive research with a quantitative approach. The notified cases of drug intoxication were collected from the Department of Informatics of the Unified Health System (DATASUS) having the variables studied: region, year, sex, circumstance, final classification and evolution. 224,901 cases of drug poisoning were studied in the aforementioned period, and through these cases it was found that there was a gradual increase in the number of notifications over the years studied, 28% in 2017. Of the notified cases 51% belonged the southeast region. The female sex was predominant, accounting for 70% of cases. The most reported circumstance of intoxication was suicide attempt (59%) and the final predominant classification was confirmed intoxication (68%). Considering the evolution of reported cases, most of them evolved to cure without sequelae (83%). The investigation made it possible to know the epidemiological profile of notified cases of drug poisoning in Brazil. From these findings, it is concluded that there is a need to implement policies to minimize the risks to human health due to the use of medicines. In addition, it is also important to incorporate the standard as a basic work tool to generate accurate and updated data in the national databases. Such factors demonstrate the importance of implementing a Toxicological Information and Assistance Center (CIAT) throughout Brazil, as well as Hospital Epidemiology Centers (NEH) to better monitor the profile of drug poisoning.
References
Bernardes, S.S. et al. (2010). Perfil das tentativas de suicídio por sobredose intencional de medicamentos atendidas por um Centro de Controle de Intoxicações do Paraná, Brasil. Caderno de Saúde Pública, 26 (7), 1366-1372. Recuperado de: http://www.scielo.br /scielo.php?script=sci_arttext&pid=S0102-311X2010000700015&lng=en& nrm=iso.
Brasil (2018). Boletim Epidemiológico: Intoxicações exógenas relacionadas ao trabalho no Brasil, 2007-2016. Recuperado de: https://portalarquivos2.saude.gov.br/images/pdf/2018/dezembro/26/2018-027.pdf.
Brasil (2018). Instruções para preenchimento da Ficha de Investigação de Intoxicação Exógena Sinan – Sistema de Informação de Agravos de Notificação. Recuperado de: < http://bvsms.saude.gov.br/bvs/publicacoes/intoxicacao_exogena_sinan.pdf>.
Hahn, R. C. et al (2013). Características de intoxicações agudas em crianças: estudo em um centro de assistência toxicológica. Brazilian Journal of Surgery and Clinical Research, 4 (1), 18-22. Recuperado de: < https://www.mastereditora.com.br/download-256>.
Levorato, C.D. et al. (2014). Fatores associados à procura por serviços de saúde numa perspectiva relacional de gênero. Ciência & Saúde Coletiva, 19 (4), 1263-1274. Recuperado de: <https://doi.org/10.1590/1413-81232014194.01242013>.
Mathias, T.L. et al. (2019). Tendências de eventos toxicológicos relacionados a medicamentos atendidos por um Centro de Informações Toxicológicas. Revista Brasileira de Epidemiologia, 22 (1), 1-13. Recuperado de: https://doi.org/10.1590/1980-549720190018.
Mendes, L.A. et al. (2017). Intoxicações por medicamentos no Brasil registradas pelo SINITOX entre 2007 e 2011. Revista de Saúde e Ciências Biológicas, 5 (2), 165-170. Recuperado de: < https://periodicos.unichristus.edu.br/jhbs/article/view/1234/425>.
Moura, E.C. et al. (2017). Percepções sobre a saúde dos homens numa perspectiva relacional de gênero, Brasil, 2014. Revista Psicologia e Saúde, 22 (1), 291-300. Recuperado de: <https://www.scielosp.org/pdf/csc/2017.v22n1/291-300/pt>.
Portaria nº 204 (17, fevereiro, 2016). Define a Lista Nacional de Notificação Compulsória de doenças, agravos e eventos de saúde pública nos serviços de saúde públicos e privados em todo o território nacional, nos termos do anexo, e dá outras providências. Recuperado de: <http://bvsms.saude.gov.br/bvs/saudelegis/gm/2016/prt0204_17_02_2016.html>.
Takahama, C.H. et al. (2014). Perfil das exposições a medicamentos por mulheres em idade reprodutiva atendidas por um Centro de Informações Toxicológicas. Ciênc. saúde coletiva, 19 (4), 1191-1199. Recuperado de:
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232014000401191&lng=en&nrm=iso.
Toscano, M. M. et al (2016). Intoxicações exógenas agudas registradas em centro de assistência toxicológica. Revista Saúde e Pesquisa, 9 (3), 425-432. Recuperado de: < https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/5450>.
Vieira, N. R. S. et al. (2016). Caracterização da produção científica sobre intoxicações exógenas: revisão integrativa da literatura. Revista Saúde-UNG-Ser, 10(1-2), 47-60. Recuperado de: http://revistas.ung.br/index.php/saude/article/view/2152/1829.
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.