Impact of poverty on Drug Resistant Tuberculosis: A review
Keywords:Tuberculosis; Drug resistance, bacterial; Social determinants of health; Health teaching.
Tuberculosis (TB) is a chronic infectious disease, caused by Mycobacterium tuberculosis, responsible for the most deaths yearly worldwide. One of the greatest obstacles in its approach, according to the World Health Organization (WHO), is the rising prevalence of drug-resistant strains, leading to treatment failure and higher mortality. The objective of this study was to carry out an integrative review of the medical literature in order to identify and analyze the impact of poverty on the incidence, prevalence and effectiveness of combating drug-resistant tuberculosis. (TBDR). A systematic literature review was carried out in Pubmed, Virtual Health Library (BVS) and Scielo databases with keywords “Drug-Resistant Tuberculosis” AND “Poverty”. Included in this review were articles published in the last 10 years in Portuguese, Spanish and English available as a free full text. There was great agreement in findings not only affirming the relationship between poverty and the occurrence of TBDR but also in the mechanisms by which it affects treatment compliance, among of which were: bigger costs to access medical care, loss of income due to work absence, prejudice, discrimination and poor food intake. Social determinants still play an unequivocal role in the incidence of TB and even more in its resistant forms, with great compromise of treatment efficacy and compliance. As a result, diminishing poverty and inequality should be considered pivotal strategies against this disease, even more so than the development of new diagnostic and treatment tools.
Baral, S. C., Aryal, Y., Bhattrai, R., King, R., & Newell, J. N. (2014). The importance of providing counselling and financial support to patients receiving treatment for multi-drug resistant TB: mixed method qualitative and pilot intervention studies. BMC public health, 14(1), 1-7.
Caws, M., Marais, B., Heemskerk, D., & Farrar, J. (2015). Tuberculosis in Adults and Children. Springer Nature.
Hutchison, C., Khan, M. S., Yoong, J., Lin, X., & Coker, R. J. (2017). Financial barriers and coping strategies: a qualitative study of accessing multidrug-resistant tuberculosis and tuberculosis care in Yunnan, China. BMC public health, 17(1), 1-11.
Kitchenham, B. (2004). Procedures for performing systematic reviews. Keele, UK, Keele University, 33(2004), 1-26.
Kozakevich, G. V., & da Silva, R. M. (2015). Tuberculose: revisão de literatura. Arquivos Catarinenses de Medicina, 44(4), 34-47.
McNally, T. W., de Wildt, G., Meza, G., & Wiskin, C. (2019). Improving outcomes for multi-drug-resistant tuberculosis in the Peruvian Amazon–a qualitative study exploring the experiences and perceptions of patients and healthcare professionals. BMC health services research, 19(1), 1-17.
Mussie, K. M., Yimer, S. A., Manyazewal, T., & Gradmann, C. (2019). Exploring local realities: Perceptions and experiences of healthcare workers on the management and control of drug-resistant tuberculosis in Addis Ababa, Ethiopia. PLoS One, 14(11), e0224277.
Peterson, M. L., Gandhi, N. R., Clennon, J., Nelson, K. N., Morris, N., Ismail, N., & Shah, N. S. (2019). Extensively drug-resistant tuberculosis ‘hotspots' and sociodemographic associations in Durban, South Africa. The International Journal of Tuberculosis and Lung Disease, 23(6), 720-727.
Pleşca, V., Ciobanu, A., Sereda, I., & Dadu, A. (2021). Do catastrophic costs impact treatment outcomes in people with rifampicin-resistant tuberculosis in the Republic of Moldova?. Monaldi Archives for Chest Disease, 91(1).
Ramma, L., Cox, H., Wilkinson, L., Foster, N., Cunnama, L., Vassall, A., & Sinanovic, E. (2015). Patients' costs associated with seeking and accessing treatment for drug-resistant tuberculosis in South Africa. The international journal of tuberculosis and lung disease, 19(12), 1513-1519.
Rudgard, W. E., Nancy, S., Gayoso, R., Barreto, M. L., Boccia, D., Smeeth, L., & Maciel, E. L. (2018). Uptake of governmental social protection and financial hardship during drug-resistant tuberculosis treatment in Rio de Janeiro, Brazil. European Respiratory Journal, 51(3).
Santos, F. L. D., Souza, L. L. L., Bruce, A. T. I., Crispim, J. D. A., Arroyo, L. H., Ramos, A. C. V., & Arcêncio, R. A. (2021). Patients’ perceptions regarding multidrug-resistant tuberculosis and barriers to seeking care in a priority city in Brazil during COVID-19 pandemic: a qualitative study. PLoS One, 16(4), e0249822.
Silva, D. R., Rabahi, M. F., Sant’Anna, C. C., Silva-Junior, J. L. R. D., Capone, D., Bombarda, S., & Mello, F. C. D. Q. (2021). Consenso sobre o diagnóstico da tuberculose da Sociedade Brasileira de Pneumologia e Tisiologia. Jornal Brasileiro de Pneumologia, 47.
Souza, L. L. L., Santos, F. L. D., Crispim, J. D. A., Fiorati, R. C., Dias, S., Bruce, A. T. I., & Arcêncio, R. A. (2021). Causes of multidrug-resistant tuberculosis from the perspectives of health providers: challenges and strategies for adherence to treatment during the COVID-19 pandemic in Brazil. BMC Health Services Research, 21(1), 1-10.
Tomita, A., Ramlall, S., Naidu, T., Mthembu, S. S., Padayatchi, N., & Burns, J. K. (2019). Major depression and household food insecurity among individuals with multidrug-resistant tuberculosis (MDR-TB) in South Africa. Social psychiatry and psychiatric epidemiology, 54(3), 387-393.
Wingfield, T., Boccia, D., Tovar, M., Gavino, A., Zevallos, K., Montoya, R., & Evans, C. A. (2014). Defining catastrophic costs and comparing their importance for adverse tuberculosis outcome with multi-drug resistance: a prospective cohort study, Peru. PLoS medicine, 11(7), e1001675.
How to Cite
Copyright (c) 2022 Vitor Santos Castejon; Mônica Santos de Melo; Thiago da Silva Mendes; Makson Gleydson Brito de Oliveira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.