Oral manifestations in pediatric patients with Acute Lymphoid Leukemia

Authors

DOI:

https://doi.org/10.33448/rsd-v11i7.30119

Keywords:

Acute Lymphoblastic Leukemia; Oral Manifestations; Oncology; Health teaching.

Abstract

Objective: To review the literature on the main oral alterations found in pediatric patients with Acute Lymphoblastic Leukemia, whether caused by the disease or by antineoplastic treatment. Methodology: This is an integrative literature review that used the PubMed, Lilacs and Scielo databases through the keywords registered in the Health Sciences Descriptors (DeCS), in which studies that addressed the proposed theme were included. in this work, available in the aforementioned databases, in English and Portuguese, between the years 2011 to 2021. Results: 514 articles were found, of these 178 were initially screened based on titles and abstracts and only 34 articles met the eligibility criteria. Conclusion: Acute Lymphoblastic Leukemia, in most cases, leads to the appearance of oral lesions resulting from the disease, especially in the gingival regions, buccal mucosa, floor of the mouth, hard and soft palate. Chemotherapy and radiotherapy for Acute Lymphoblastic Leukemia are effective antineoplastic therapies, however, their side effects affect the oral cavity, with the most recurrent oral complications being: mucositis, candidiasis and radiation caries. It is of great value that the dentist is inserted in the multidisciplinary context, at the hospital and oncological level, as part of the success of the treatment of this leukemia, whether as a preventive or therapeutic approach.

Author Biographies

Ana Clara Alves Santiago Silveira, Faculdade Independente do Nordeste

Undergraduate student in Dentistry, Faculdade Independente do Nordeste - FAINOR. Member of the PIVIC research group (2019-2022), with an emphasis on stomatology and hospital dentistry.

Luara Novaes Coutinho, Faculdade Independente do Nordeste

Student of the 10th semester of the Dentistry course at Faculdade Independente do Nordeste - FAINOR.

Gefter Thiago Batista Correa, Faculdade Independente do Nordeste

PhD in Molecular Medicine from the Federal University of Minas Gerais (2015). Master's in Health Sciences with emphasis on oral pathology from the State University of Montes Claros (2011). He is currently a professor of oral diagnosis at Faculdade Independente do Nordeste and professor of oral pathology at Faculdade Independente do Nordeste. Graduated in Dentistry from the State University of Montes Claros (2008).

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Published

24/05/2022

How to Cite

SILVEIRA, A. C. A. S. .; COUTINHO, L. N. .; CORREA, G. T. B. . Oral manifestations in pediatric patients with Acute Lymphoid Leukemia . Research, Society and Development, [S. l.], v. 11, n. 7, p. e27711730119, 2022. DOI: 10.33448/rsd-v11i7.30119. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30119. Acesso em: 6 jul. 2022.

Issue

Section

Review Article