Paracoccidioidomycosis mimicking adrenal cancer: a case report

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30282

Keywords:

Paracoccidioidomycosis; Neoplasms of the adrenal glands; Adrenal cancer.

Abstract

Paracoccidioidomycosis is a pathology that presents an immense range of clinical manifestations, with fungal etiology and a significant rate of complications. The pathophysiology is related to the immune response of each host, and can be acute, subacute and chronic. The most reported clinical picture is related to pulmonary symptoms, but the characteristics can be variable because it is a hematogenous infection. There is a frequent association with workers in rural areas and a considerable relationship with males, with endemic regions in which most of the population is affected, but with the most varied clinical conditions. Diagnosis is based on microscopic visualization of fungal elements suggestive of Paracoccidioides spp. Treatment is related to the severity and symptoms presented by the individual. The aim of this study is to report a case of paracoccidioidomycosis mimicking adrenal cancer.

References

Benard, G. (2008). An overview of the immunopathology of human paracoccidioidomycosis. Mycopathologia. 165,4-5.

Borges, S. R. C., et al. (2014). Itraconazole vs. trimethoprim-sulfamethoxazole: A comparative cohort study of 200 patients with paracoccidioidomycosis. Medical mycology, 52,3.

Carvalho, F. M. C., et al. (2016). Polymorphisms on IFNG, IL12B and IL12RB1 genes and paracoccidioidomycosis in the Brazilian population. Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseasesvol. 43.

Costa, A. N., et al. (2013). The lung in paracoccidioidomycosis: new insights into old problems. Clinical science – clinics 68 (4).

Hahn, R.C., et al. (2019). Clinical and epidemiological features of paracoccidioidomycosis due to Paracoccidioides lutzii. PLoS neglected tropical diseases vol. 13,6 e0007437. 4 Jun.

Lacaz, C. S., et al. (2002). Tratado de Micologia médica; Prefácio: Bertrand Dupont. (9a ed.), Sarvier.

Martinez R. (2017). New trends in paracoccidioidomycosis epidemiology. J Fungi.

Morejón, K. M. L., et al. (2009). Paracoccidioidomycosis in patients infected with and not infected with human immunodeficiency virus: a case-control study. The American journal of tropical medicine and hygiene vol. 80,3.

Nucci, M. & Colombo, A. (2019). Micologia e epidemiologia da paracoccidioidomicose. UpToDate.

Nucci, M. & Colombo, A. (2020). Manifestações clínicas e diagnóstico da paracoccidioidomicose crônica. UpToDate.

Oliveira, S.J., et al. (2002). Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: comparison with infected and non-infected controls. Microbes and infection vol. 4,2.

Pereira A. S., Shitsuka D. M., Parreira F. J. & Shitsuka R. (2018). Metodologia da pesquisa científica. UFSM. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Compatacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1

Peçanha, P. M., et al. (2016). Amphotericin B lipid complex in the treatment of severe paracoccidioidomycosis: a case series. International journal of antimicrobial agentsvol. 48,4.

Restrepo, A., et al. (2008). Pulmonary paracoccidioidomycosis. Seminars in respiratory and critical care medicine vol. 29,2.

Shikanai-Yatsuda, M. A., et al. (2018). II Consenso Brasileiro em Paracoccidioidomicose. Epidemiol. Serv. Saúde.

Silveira, L. H., et al. (2008). Occurrence of Antibodies to Paracoccidioides brasiliensis in dairy cattle from Mato Grosso do Sul, Brazil. Mycopathologia 165,6.

Thompson, G. R., et al. (2016). Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America vol. 63,3.

Travassos, L. R., et al. (2008). Treatment options for paracoccidioidomycosis and new strategies investigated. Expert review of anti-infective therapy 6,2.

Published

12/06/2022

How to Cite

MIACAVA, M. L. .; SANTOS, T. F. dos; GALHARDO, C. A. V. . Paracoccidioidomycosis mimicking adrenal cancer: a case report . Research, Society and Development, [S. l.], v. 11, n. 8, p. e12311830282, 2022. DOI: 10.33448/rsd-v11i8.30282. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30282. Acesso em: 19 apr. 2024.

Issue

Section

Health Sciences