Interventions to reduce errors with potentially dangerous drugs in hospitalized children: an integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30456

Keywords:

Child; Security Measures; Patient Safety; Medication errors; Health teaching.

Abstract

Errors can occur at any stage of drug therapy. Potentially dangerous drugs are worth mentioning because they are more likely to harm the patient, especially children, as they have particularities inherent to their age. We sought to identify barriers that reduce errors with potentially dangerous medications in hospitalized children. This is an integrative review, whose search took place between August and September 2020, in the Cochrane Library, PUBMED, Google Scholar databases, and in the TRIP DATABASE meta-searcher, to answer the guiding question: “What are the interventions in reducing of errors with potentially dangerous drugs in hospitalized children?”. Searches in the researched databases captured 298 references. After the exclusions, 76 studies were selected to be read in full; of these, 6 articles were selected to compose this review. They were grouped into three categories: Educational strategies; Technological resources and; Assistance activities. The studies address several strategies for reducing medication errors. Here, the importance of combining strategies for the safe use of potentially dangerous drugs in children is highlighted.

References

Alghamdi, A. A., Keers, R. N., Sutherland, A., & Ashcroft, D. M. (2019). Prevalence and Nature of Medication Errors and Preventable Adverse Drug Events in Paediatric and Neonatal Intensive Care Settings: A Systematic Review. Drug Safety, 42, 1423-1436. https://doi.org/10.1007/s40264-019-00856-9

Bastos, W.D.G., Leal, P. S., Rodrigues, J. F. B., Melo, D. F. S. & Randau, K. P. (2022). Preparo e administração de medicamentos de alta vigilância na perspectiva da segurança do paciente. Research, Society and Development, 11 (2), e4511225491. http://dx.doi.org/10.33448/rsd-v11i2.25491

Brasil. Ministério da Saúde. Agência Nacional de Vigilância Sanitária (ANVISA) (2013). Protocolo de Segurança na Prescrição, uso e Administração de Medicamentos: protocolo coordenado pelo Ministério da Saúde e ANVISA em parceria com FIOCRUZ e FHEMIG. https://portaldeboaspraticas.iff.fiocruz.br/wp-content/uploads/2020/01/protoc_identificacaoPaciente.pdf

Carvalho, J. R. de G., Valle, K. R. do, Menezes, A. C., Santos, G. dos, Schlosser, C. N., Silveira, E. A. A da, ... Trevisan D. D. (2021). Simulação no ensino da administração de medicamentos de alta vigilância para enfermeiros: breve visão geral. Research, Society and Development, 10 (12), e523101217576. http://dx.doi.org/10.33448/rsd-v10i12.17576

Dedefo, M. G., Mitike, A. H., & Angamo, M. T. (2016). Incidence and determinants of medication errors and adverse drug events among hospitalized children in West Ethiopia. BMC Pediatrics, 16 (1). https://doi.org/10.1186/s12887-016-0619-5

Howlett, M. M., Cleary, B. J., & Breatnach, C. V. (2018). Defining electronic-prescribing and infusion-related medication errors in paediatric intensive care: a Delphi study. BMC Medical Informatics and Decision Making, 18 (1). https://doi.org/10.1186/s12911-018-0713-8

Instituto para Práticas Seguras no Uso de Medicamentos (2015). Medicamentos De Alta Vigilância De Uso Hospitalar e Ambulatorial: listas atualizadas 2015. Boletim ISMP Brasil, 4 (3). https://www.ismp-brasil.org/site/wp-content/uploads/2015/12/V4N3.pdf

Instituto para Práticas Seguras no Uso de Medicamentos (2019). Medicamentos De Alta Vigilância De Uso Hospitalar e Ambulatorial: lista atualizada 2019. Boletim ISMP Brasil, 8 (1). https://www.ismp-brasil.org/site/wp-content/uploads/2019/02/615-boletim-ismp-fevereiro-2019.pdf

Izadpanah F, Nikfar S, Bakhshi Imcheh F, Amini M, Zargaran M. (2018). Assessment of Frequency and Causes of Medication Errors in Pediatrics and Emergency Wards of Teaching Hospitals Affiliated to Tehran University of Medical Sciences (24 Hospitals). J Med Life, 11(4), 299–305. https:// doi: 10.25122/jml-2018-0046.

Joint Commission (2021). Preventing pediatric medication errors. Sentinel Event Alert, 39. https://www.jointcommission.org/-/media/tjc/documents/resources/patient-safety-topics/sentinel-event/sea-39-ped-med-errors-rev-final-4-14-21.pdf

Julca, C. S. M., Rocha, P. K., Tomazoni, A., Manzo, B. F., Souza, S. de, & Anders, J. C. (2018). Utilização de barreiras de segurança no preparo de drogas vasoativas e sedativos/analgésicos em terapia intensiva pediátrica. Cogitare Enfermagem, 23 (4), e54247. https://doi.org/10.5380/ce.v23i4.54247

Kaufmann, J., Wolf, A. R., Becke, K., Laschat, M., Wappler, F., & Engelhardt, T. (2017). Drug safety in paediatric anaesthesia. British Journal of Anaesthesia, 118 (5), 670–679. https://doi.org/10.1093/bja/aex072

Leahy, I. C., Lavoie, M., Zurakowski, D., Baier, A. W., & Brustowicz, R. M. (2018). Medication errors in a pediatric anesthesia setting: incidence, etiologies, and error reduction strategies. Journal of Clinical Anesthesia, 49, 107–111. https://doi.org/10.1016/j.jclinane.2018.05.011

Manias, E., Cranswick, N., Newall, F., Rosenfeld, E., Weiner, C., Williams, A., … Kinney, S. (2018). Medication error trends and effects of person-related, environment-related and communication-related factors on medication errors in a paediatric hospital. Journal of Paediatrics and Child Health, 55 (3), 320–326. https://doi.org/10.1111/jpc.14193

Martin, L. D., Grigg, E. B., Verma, S., Latham, G. J., Rampersad, S. E., & Martin, L. D. (2017). Outcomes of a Failure Mode and Effects Analysis for medication errors in pediatric anesthesia. Pediatric Anesthesia, 27 (6), 571–580. https://doi.org/10.1111/pan.13136

Mekory, T. M., Bahat, H., Bar-Oz, B., Tal, O., Berkovitch, M., & Kozer, E. (2017). The proportion of errors in medical prescriptions and their executions among hospitalized children before and during accreditation. International Journal for Quality in Health Care, 29 (3), 366–370. https://doi.org/10.1093/intqhc/mzx031

Mendes, K. D. S., Silveira, R. C. de C. P., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto - Enfermagem, 17(4), 758–764. https://doi.org/10.1590/s0104-07072008000400018

Mieiro, D. B., Oliveira, É. B. C. de, Fonseca, R. E. P. da, Mininel, V. A., Zem-Mascarenhas, S. H., & Machado, R. C. (2019). Strategies to minimize medication errors in emergency units: an integrative review. Revista Brasileira de Enfermagem, 72(suppl 1), 307–314. https://doi.org/10.1590/0034-7167-2017-0658

Monteiro, D. P., Britto, R. R., Carvalho, M. L. V., Montemezzo, D., Parreira, V. F., & Pereira, D. A. G. (2014). Shuttle walking test como instrumento de avaliação da capacidade funcional: uma revisão da literatura. Ciência & Saúde, 7 (2), 92-97. https://doi.org/10.15448/1983-652x.2014.2.16580

Murray, B., Streitz, M. J., Hilliard, M., & Maddry, J. K. (2019). Evaluation of an Electronic Dosing Calculator to Reduce Pediatric Medication Errors. Clinical Pediatrics, 58 (4), 413–416. https://doi.org/10.1177/0009922818821871

Rashed, A. N., Whittlesea, C., Davies, C., Forbes, B., & Tomlin, S. (2019). Standardised concentrations of morphine infusions for nurse/patient-controlled analgesia use in children. BMC Anesthesiology, 19(1). https://doi.org/10.1186/s12871-019-0697-7

Reis, M. A. S. dos, Gabriel, C. S., Zanetti, A. C. B., Bernardes, A., Laus, A. M., & Pereira, L. R. L. (2018). Medicamentos potencialmente perigosos: identificação de riscos e barreiras de prevenção de erros em terapia intensiva. Texto & Contexto - Enfermagem, 27 (2). https://doi.org/10.1590/0104-07072018005710016

Souza, A. S. C. de, Marinho, D. T., Silva, J. S., Santos, G. M. G., Silva, R. M. R., & Oliveira, M. M. C. (2018). Eventos adversos e prática segura com medicação em pediatria: revisão integrativa. Revista Enfermagem Atual in Derme, 84 (22), 157-170. https://doi.org/10.31011/reaid-2018-v.84-n.22-art.274

Volpatto, B. M., Wegner, W., Gerhardt, L. M., Pedro, E. N. R., Cruz, S. da S., & Bandeira, L. E. (2017). Erros de medicação em pediatria e estratégias de prevenção: revisão integrativa. Cogitare Enfermagem, 22 (1), e45132. https://doi.org/10.5380/ce.v22i1.45132

World Health Organization (2017). Medication without harm: WHO Global Patient Safety Challenge. Geneva: World Health Organization. https://www.who.int/publications/i/item/WHO-HIS-SDS-2017.6

Published

12/06/2022

How to Cite

ARAUJO, D. S.; GARCIA, A. dos S. .; SILVA, C. R. L. da. Interventions to reduce errors with potentially dangerous drugs in hospitalized children: an integrative review. Research, Society and Development, [S. l.], v. 11, n. 8, p. e13011830456, 2022. DOI: 10.33448/rsd-v11i8.30456. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30456. Acesso em: 20 nov. 2024.

Issue

Section

Health Sciences