Oral surgery in patients undergoing head and neck radiotherapy

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30684

Keywords:

Radiotherapy; Oral complications; Head and neck cancer.

Abstract

Head and neck cancer (PPC) corresponds to tumors located in the skin, oral cavity, lips, salivary glands, larynx, pharynx, nasal cavity, paranasal sinuses, external acoustic meatus and middle ear. It affects people of both sexes, but with a greater predilection for males and over 40 years of age. The vast majority of patients with HNC are treated with high-dose radiotherapy in this region, commonly administered in daily fractions, over a period of 5 to 7 weeks. This treatment modality generates harmful effects on oral and maxillofacial tissues in patients, such as a marked increase in the risk of dental caries after exposure to radiation. In view of the above, this study aimed to review the literature on oral surgery in patients undergoing head and neck radiotherapy, addressing the oral manifestations resulting from head and neck radiotherapy and oral management strategies for head and neck radiotherapy. For the construction of this article, a bibliographic survey was carried out in the databases SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect, using the Mendeley reference manager. In cases of need for surgical intervention after radiotherapy treatment, extractions should be performed in a minimally invasive way and wait until there is complete healing of the alveolus to start radiotherapy. During irradiation, surgical procedures are not indicated and the dentist's main objective is to prevent or treat oral complications that may arise. Surgical procedures can be performed 6 months after the end of radiotherapy, observing similar results when compared to extractions before radiotherapy.

References

Agarwal, Padmanidhi, H. R. Shiva Kumar, & Kirthi Kumar Rai. (2016). “Trismus in Oral Cancer Patients Undergoing Surgery and Radiotherapy.” Journal of Oral Biology and Craniofacial Research 6:S9–13.

Chiu, Y-H, Wen-Hsuan T., Jenq-Yuh K., & Tyng-Guey W. (2021). “Radiation-Induced Swallowing Dysfunction in Patients with Head and Neck Cancer: A Literature Review.” Journal of the Formosan Medical Association.

Davies, A. N., & Jo T. (2015). “Parasympathomimetic Drugs for the Treatment of Salivary Gland Dysfunction Due to Radiotherapy.” Cochrane Database of Systematic Reviews 2015(10).

Eraj, S., & David J. S. (2022). “PET/CT: Radiation Therapy Planning in Head and Neck Cancer.” PET Clinics 17(2):297–305.

Frankart, A. J., Michael J. Frankart, B. C., Alice L. T., Deepak G. K., and Vinita T. (2021) “Osteoradionecrosis: Exposing the Evidence Not the Bone.” International Journal of Radiation Oncology*Biology*Physics 109(5):1206–18.

Gómez, G. J. Á. et al. (2017) “Alterations Found in the Mouth of Patients Treated with Head and Neck Radiotherapy. Medellin, Colombia.” Revista Odontológica Mexicana 21(2):e86–96.

Guss, Z. D. (2022) “Head and Neck Radiation Therapy: From Consultation to Survivorship and Future Directions.” Surgical Clinics of North America 102(2):241–49.

Jafari, A., Arezoo A., & Kimia G. (2021) “The Etiologies and Considerations of Dysgeusia: A Review of Literature.” Journal of Oral Biosciences.

Kawashita, Y., Sakiko S., Masahiro U., & Toshiyuki S. (2020) “Oral Management Strategies for Radiotherapy of Head and Neck Cancer.” Japanese Dental Science Review 56(1):62–67.

Lalla, R. V, Nathaniel S. Treister, T. P. Sollecito, B. L. Schmidt, L. L. Patton, E. S. Helgeson, A. L., Cynthia Rybczyk, R. D., Upendra Hegde, T. S. Boyd, T. G. D., & Michael T. B. (2022). “Radiation Therapy for Head and Neck Cancer Leads to Gingival Recession Associated with Dental Caries.” Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 133(5):539–46.

Lye, K. W., J. Wee, F. Gao, P. S. H. Neo, Y. L. Soong, & C. Y. P. (2007). “The Effect of Prior Radiation Therapy for Treatment of Nasopharyngeal Cancer on Wound Healing Following Extractions: Incidence of Complications and Risk Factors.” International Journal of Oral and Maxillofacial Surgery 36(4):315–20.

Milgrom, Sarah A., Peter van Luijk, Ramiro Pino, Cecile M. Ronckers, Leontien C. Kremer, Paul W. Gidley, David R. Grosshans, Siddhartha Laskar, M. Fatih Okcu, Louis S. Constine, and Arnold C. Paulino. 2021. “Salivary and Dental Complications in Childhood Cancer Survivors Treated With Radiation Therapy to the Head and Neck: A Pediatric Normal Tissue Effects in the Clinic (PENTEC) Comprehensive Review.” International Journal of Radiation Oncology*Biology*Physics.

Mody, Mayur D., James W. Rocco, Sue S. Yom, Robert I. Haddad, & Nabil F. Saba. (2021) “Head and Neck Cancer.” The Lancet.

Musha, A., et al. (2021). “Clinical Features and Dosimetric Evaluation of Carbon Ion Radiation-Induced Osteoradionecrosis of Mandible in Head and Neck Tumors.” Radiotherapy and Oncology 161:205–10.

Oladega, A. et al. (2021) “The Process of Developing Consensus Guidelines by Dental Oncologists for Pre-Radiotherapy Dental Care in Head and Neck Cancer Patients Using the Modified Delphi Technique.” Journal of Evidence Based Dental Practice 101620.

Pereira, A., et al. (2018) Método Qualitativo, Quantitativo Ou Quali-Quanti.

Ribeiro, G. H., et al. (2018) “Osteonecrosis of the Jaws: A Review and Update in Etiology and Treatment.” Brazilian Journal of Otorhinolaryngology 84(1):102–8.

Scherpenhuizen, A. et al. (2015) “The Effect of Exercise Therapy in Head and Neck Cancer Patients in the Treatment of Radiotherapy-Induced Trismus: A Systematic Review.” Oral Oncology 51(8):745–50.

Silva, I. M. V et al. (2021) “Association of Xerostomia and Taste Alterations of Patients Receiving Antineoplastic Chemotherapy: A Cause for Nutritional Concern.” Clinical Nutrition ESPEN 43:532–35.

Soutome, S. et al. (2021) “Risk Factors for Severe Radiation-Induced Oral Mucositis in Patients with Oral Cancer.” Journal of Dental Sciences 16(4):1241–46.

Tawfik, G. M., et al. (2021) “Association between Radiotherapy and Obstructive Sleep Apnea in Head and Neck Cancer Patients: A Systematic Review and Meta-Analysis.” Auris Nasus Larynx 48(6):1126–34.

Taylor, C. L., & James M. P. (2022) “The Tooth Hurts: Dental Health After Radiation Therapy for Head and Neck Cancer.” International Journal of Radiation Oncology*Biology*Physics 113(2):331–34.

Weng, C-T. et al. (2021) “Oral Microbiota in Xerostomia Patients - A Preliminary Study.” Journal of Dental Sciences.

Y, Kawashita, Hayashida S, Funahara M, Umeda M, & Saito T. (2014) “Prophylactic Bundle for Radiation-Induced Oral Mucositis in Oral or Oropharyngeal Cancer Patients.” Journal of Cancer Research & Therapy 2(1):9–13.

Published

07/06/2022

How to Cite

FERNANDES, J. D. L.; LOPES, G. M. .; FERNANDES, N. D. L. .; RODRIGUES , M. C.; CARNEIRO , G. K. M.; CARNEIRO , K. H. da S.; SILVA, J. R. da; PEREIRA, L. D. .; FERREIRA, G. R. S. .; CORREA, L. F. A. . Oral surgery in patients undergoing head and neck radiotherapy. Research, Society and Development, [S. l.], v. 11, n. 8, p. e2511830684, 2022. DOI: 10.33448/rsd-v11i8.30684. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30684. Acesso em: 25 nov. 2024.

Issue

Section

Health Sciences