Oral surgery in patients undergoing head and neck radiotherapy
DOI:
https://doi.org/10.33448/rsd-v11i8.30684Keywords:
Radiotherapy; Oral complications; Head and neck cancer.Abstract
Head and neck cancer (PPC) corresponds to tumors located in the skin, oral cavity, lips, salivary glands, larynx, pharynx, nasal cavity, paranasal sinuses, external acoustic meatus and middle ear. It affects people of both sexes, but with a greater predilection for males and over 40 years of age. The vast majority of patients with HNC are treated with high-dose radiotherapy in this region, commonly administered in daily fractions, over a period of 5 to 7 weeks. This treatment modality generates harmful effects on oral and maxillofacial tissues in patients, such as a marked increase in the risk of dental caries after exposure to radiation. In view of the above, this study aimed to review the literature on oral surgery in patients undergoing head and neck radiotherapy, addressing the oral manifestations resulting from head and neck radiotherapy and oral management strategies for head and neck radiotherapy. For the construction of this article, a bibliographic survey was carried out in the databases SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect, using the Mendeley reference manager. In cases of need for surgical intervention after radiotherapy treatment, extractions should be performed in a minimally invasive way and wait until there is complete healing of the alveolus to start radiotherapy. During irradiation, surgical procedures are not indicated and the dentist's main objective is to prevent or treat oral complications that may arise. Surgical procedures can be performed 6 months after the end of radiotherapy, observing similar results when compared to extractions before radiotherapy.
References
Agarwal, Padmanidhi, H. R. Shiva Kumar, & Kirthi Kumar Rai. (2016). “Trismus in Oral Cancer Patients Undergoing Surgery and Radiotherapy.” Journal of Oral Biology and Craniofacial Research 6:S9–13.
Chiu, Y-H, Wen-Hsuan T., Jenq-Yuh K., & Tyng-Guey W. (2021). “Radiation-Induced Swallowing Dysfunction in Patients with Head and Neck Cancer: A Literature Review.” Journal of the Formosan Medical Association.
Davies, A. N., & Jo T. (2015). “Parasympathomimetic Drugs for the Treatment of Salivary Gland Dysfunction Due to Radiotherapy.” Cochrane Database of Systematic Reviews 2015(10).
Eraj, S., & David J. S. (2022). “PET/CT: Radiation Therapy Planning in Head and Neck Cancer.” PET Clinics 17(2):297–305.
Frankart, A. J., Michael J. Frankart, B. C., Alice L. T., Deepak G. K., and Vinita T. (2021) “Osteoradionecrosis: Exposing the Evidence Not the Bone.” International Journal of Radiation Oncology*Biology*Physics 109(5):1206–18.
Gómez, G. J. Á. et al. (2017) “Alterations Found in the Mouth of Patients Treated with Head and Neck Radiotherapy. Medellin, Colombia.” Revista Odontológica Mexicana 21(2):e86–96.
Guss, Z. D. (2022) “Head and Neck Radiation Therapy: From Consultation to Survivorship and Future Directions.” Surgical Clinics of North America 102(2):241–49.
Jafari, A., Arezoo A., & Kimia G. (2021) “The Etiologies and Considerations of Dysgeusia: A Review of Literature.” Journal of Oral Biosciences.
Kawashita, Y., Sakiko S., Masahiro U., & Toshiyuki S. (2020) “Oral Management Strategies for Radiotherapy of Head and Neck Cancer.” Japanese Dental Science Review 56(1):62–67.
Lalla, R. V, Nathaniel S. Treister, T. P. Sollecito, B. L. Schmidt, L. L. Patton, E. S. Helgeson, A. L., Cynthia Rybczyk, R. D., Upendra Hegde, T. S. Boyd, T. G. D., & Michael T. B. (2022). “Radiation Therapy for Head and Neck Cancer Leads to Gingival Recession Associated with Dental Caries.” Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 133(5):539–46.
Lye, K. W., J. Wee, F. Gao, P. S. H. Neo, Y. L. Soong, & C. Y. P. (2007). “The Effect of Prior Radiation Therapy for Treatment of Nasopharyngeal Cancer on Wound Healing Following Extractions: Incidence of Complications and Risk Factors.” International Journal of Oral and Maxillofacial Surgery 36(4):315–20.
Milgrom, Sarah A., Peter van Luijk, Ramiro Pino, Cecile M. Ronckers, Leontien C. Kremer, Paul W. Gidley, David R. Grosshans, Siddhartha Laskar, M. Fatih Okcu, Louis S. Constine, and Arnold C. Paulino. 2021. “Salivary and Dental Complications in Childhood Cancer Survivors Treated With Radiation Therapy to the Head and Neck: A Pediatric Normal Tissue Effects in the Clinic (PENTEC) Comprehensive Review.” International Journal of Radiation Oncology*Biology*Physics.
Mody, Mayur D., James W. Rocco, Sue S. Yom, Robert I. Haddad, & Nabil F. Saba. (2021) “Head and Neck Cancer.” The Lancet.
Musha, A., et al. (2021). “Clinical Features and Dosimetric Evaluation of Carbon Ion Radiation-Induced Osteoradionecrosis of Mandible in Head and Neck Tumors.” Radiotherapy and Oncology 161:205–10.
Oladega, A. et al. (2021) “The Process of Developing Consensus Guidelines by Dental Oncologists for Pre-Radiotherapy Dental Care in Head and Neck Cancer Patients Using the Modified Delphi Technique.” Journal of Evidence Based Dental Practice 101620.
Pereira, A., et al. (2018) Método Qualitativo, Quantitativo Ou Quali-Quanti.
Ribeiro, G. H., et al. (2018) “Osteonecrosis of the Jaws: A Review and Update in Etiology and Treatment.” Brazilian Journal of Otorhinolaryngology 84(1):102–8.
Scherpenhuizen, A. et al. (2015) “The Effect of Exercise Therapy in Head and Neck Cancer Patients in the Treatment of Radiotherapy-Induced Trismus: A Systematic Review.” Oral Oncology 51(8):745–50.
Silva, I. M. V et al. (2021) “Association of Xerostomia and Taste Alterations of Patients Receiving Antineoplastic Chemotherapy: A Cause for Nutritional Concern.” Clinical Nutrition ESPEN 43:532–35.
Soutome, S. et al. (2021) “Risk Factors for Severe Radiation-Induced Oral Mucositis in Patients with Oral Cancer.” Journal of Dental Sciences 16(4):1241–46.
Tawfik, G. M., et al. (2021) “Association between Radiotherapy and Obstructive Sleep Apnea in Head and Neck Cancer Patients: A Systematic Review and Meta-Analysis.” Auris Nasus Larynx 48(6):1126–34.
Taylor, C. L., & James M. P. (2022) “The Tooth Hurts: Dental Health After Radiation Therapy for Head and Neck Cancer.” International Journal of Radiation Oncology*Biology*Physics 113(2):331–34.
Weng, C-T. et al. (2021) “Oral Microbiota in Xerostomia Patients - A Preliminary Study.” Journal of Dental Sciences.
Y, Kawashita, Hayashida S, Funahara M, Umeda M, & Saito T. (2014) “Prophylactic Bundle for Radiation-Induced Oral Mucositis in Oral or Oropharyngeal Cancer Patients.” Journal of Cancer Research & Therapy 2(1):9–13.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Jefferson Douglas Lima Fernandes; Geovana Martins Lopes; Nívia Delamoniky Lima Fernandes; Marcelo Costa Rodrigues ; Grace Kelly Martins Carneiro ; Kaio Henrique da Silva Carneiro ; Jefferson Rodrigo da Silva; Lucas Dantas Pereira; Gildo Renê Sousa Ferreira; Luis Fernando Alves Correa
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.