Feline sporotrichosis: Clinical conduct, diagnosis and treatment recommended in the municipality of Vitória- ES

Authors

DOI:

https://doi.org/10.33448/rsd-v11i10.31028

Keywords:

Zoonosis; Itraconazole; Potassium iodide; Sporothrix sp; Cats.

Abstract

Sporotrichosis is a zoonosis transmitted by Sporothrix sp that causes cutaneous and disseminated lesions, with frequent cosmopolitan distribution in regions with hot and humid climates. We analyzed 270 cases, 95 of which presented clinical signs suggestive of sporotrichosis, being analyzed and verified. To collect the material, physical or chemical contention (0.2ml/kg of Tiletamine 125mg + Zolazepan 125mg) was performed. The material was collected by swabs, or by imprint method, in extensive and exudative lesions, and identified, packaged and sent to the laboratory for confirmation of the disease. 95 animals were diagnosed with sporotrichosis; 23 (24.0%) were euthanized immediately because they arrived at the clinic with advanced stages of the disease and 72 (76.0%) were submitted to the proposed treatment (itraconazole or itraconazole + potassium iodide). After treatment, 69 (94.2%) were clinically cured and 3 (5.8%) were euthanized due to therapeutic inefficiency.  The highest incidence of this pathology was observed in animals from regions surrounded by mangroves, adjacent forests, with low-income populations and lack of sanitary services.Therefore, it is concluded that felines between 23 months to 35 weeks, classified in stages I and II of treatment, obtained satisfactory cure rates and the therapeutic protocol used by the sporotrichosis service of the zoonosis, ,  department of Zoonosis, of the Environmental Health Surveillance Center. it was effective. 

References

Andrade, A., Pinto, S.C., Oliveira, de R.S. (2002). Animais de laboratório: criação e experimentação [Internet]. Rio de Janeiro: Editora FIOCRUZ. https://books.scielo.org/id/sfwtj.

Almeida, A.J., Reis, N.F., Lourenço, C.S., Costa, N.Q., Bernardino, M.L.A., Motta, da O.V. (2018). Esporotricose em felinos domésticos (Felis catus domesticus) em Campos dos Goytacazes. Revista Pesquisa Veterinária Brasileira. 38(7). Disponível: https://doi.org/10.1590/1678-5150-PVB-5559.

Barros, M.B.L., Paes, R.A., Schubach, A.O. (2011). Sporothrix schenckii and Sporotrichosis. Clin. Microbiol. Rev. 24(4):633-654. .Disponível: https:// doi:10.1128/CMR.00007-11.

Falqueto, A., Maifrede, S.B., Rubeiro, M.A. (2012). Unusual clinical presentation of Sporotrichosis in three members of one family. International Journal of Dermatology. 21(4):434-438. https://doi: 10.1111/j.1365-4632.2011.5085.x.

Chaves, A.R., Campos, M.P., Barros, M.B.L., Carmo, C.N., Gremiao, I.D.F., Pereira, S.A. et al (2012). Treatment Abandonment in Feline Sporotrichosis - Study of 147 cases. Zoonoses and Public Health. 60(2):149-153. Disponível: https:// doi: 10.1111/j.1863-2378.2012.01506.x.

Conselho Nacional de Controle de Experimentação Animal (2019). Processo de nº 4324050/2020 do Parecer da Comissão Técnica de Pesquisa da SEMUS/ PMV.

Gram, W. D. (2002). Sporotrichosis: Subcutaneous Mycosis. In: Troy D, editor. The 5 Minute Veterinary Consult: Small Animal Companion. Philadelphia: Lippincott Williams & Wilkins; 1(1):325-328

Gremião, I. D. F., Rocha, E. M. S., Montenegro, M., Carneiro, A. J. B., Xavier, M. O., Farias, M. R., Monti, F., Mansho, W, R. H. M., Pereira, R. H. M. A., Pereira S. A., Lopes-Bezerra, L. M. (2020). Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision, Brazilian Journal of Microbiology. 52(1):107–124. https://doi.org/10.1007/s42770-020-00365-3.

Larsson, C.E. (2010). Esporotricosis. In: Gomez N; Guida N. Enfermedades infecciosas em de caninos y felinos. Buenos Aires: Intermedica; 48(3): 433-440. https://www.researchgate.net/publication/305202778_Esporotricose.

Larsson, C.E. (2011). Sporotrichosis. Brazilian Journal of Veterinary Research and Animal Science. 54(4): 439-444. https://www.revistas.usp.br/bjvras/article/view/133772/0

Macêdo-Sales, P.A., Souto, S.R.L.S., Destefani, C.A., Lucena, R.P., Rocha, E.M.S., Baptista, A.R.S. (2018). Diagnóstico laboratorial da esporotricose felina em amostras coletadas no estado do Rio de Janeiro, Brasil: limitações da citopatologia por imprint. Rev Pan-Amaz Saude. 9(2):13-19. http://revista.iec.gov.br/submit/index.php/rpas/article/view/337.

Madrid, I.M., Mattei, A.S., Fernandes, C.G., Nobre, M.O., Meireles, M.C.A. (2011). Epidemiological findings and laboratory evaluation of sporotrichosis: a description of 103 cases in cats and dogs in southern Brazil. Mycopathologia. 173(4):265-273. https://www.ncbi.nlm.nih.gov/pubmed/22143899.

Mafra, A.P. (2016). Protocolo de manejo clínico e Vigilância em Saúde para esporotricose no estado do Paraná. Curitiba. https://www.saude.pr.gov.br/sites/default/arquivos_restritos/files/documento/2020-04/protocolobrucelose2018.pdf

Moura, A., Resende, A.M., Faria, de B.W.F., Emediato, de C.C.F., Starling, C.C.D., Santiago, C.F. et al (2018). Esporotricose, protocolo de entendimento da doença em Belo Horizonte. Revista online. 1(1): 12-13. file:///C:/Users/betha/Downloads/diagnastico_epidemiolagico_da_esporotricose_em_belo_horizonte_minas_g.pdf

Nuñez, P., Mendonça, T.D.P., Toledo, A. (2019). Nota Técnica S/SUBVISA nº 03/19 Protocolo de Tratamento da Esporotricose Animal S/Subvisa. https:// doi: 10.13140/RG.2.2.24502.93768.

Pereira, A.S. (2009). Esporotricose felina: estudo terapêutico no Rio de Janeiro [Dissertação]. Rio de Janeiro (RJ): Fundação Oswaldo Cruz- Instituto Nacional de Infectologia Evandro Chagas. https://www.arca.fiocruz.br/handle/icict/28075

Pereira, S.A., Menezes, R.C., Gremião, I.D.F., Silva, J.N., Honse, C.O., Figueiredo, F.B. et al (2010). Response to azolic antifungal agents for treating feline sporotrichosis. Vet Rec. 166(10):4-290. https:// doi: 10.1136/vr.b4752

Pires, C. (2017). Revisão de literatura: esporotricose felina. Revista de Educação Continuada em Medicina Veterinária e Zootecnia do CRMV-SP, 15(1):16-23. https://doi.org/10.36440/recmvz.v15i1.36758

Reis, E.G., Gremião, I.D.F., Kitada, A.A.B., Rocha, R.F.D.B., Castro, V.S.P., Barros, M.B.L., Menezes, R.C., Pereira, S.A., Schubach, T.M.P. (2012). Potassium iodine capsule treatment of feline sporotrichosis. Journal of feline medicine and surgery. 14(6):399-404. https:// doi: 10.1177/1098612x12441317.

Santos, A.F., Rocha, B.D., Bastos, de C.V., Oliveira, De C.S.F., Soares, de D.F.M., Pais, G.C.T. et al (2018). Guia Prático para enfrentamento da Esporotricose Felina em Minas Gerais. Revista V&Z Em Minas. 38(137):25-27. http://www.crmvmg.gov.br/arquivos/ascom/esporo.pdf.

Schubach, T.M., Schubach, A., Okamoto, T., Barros, M.B., Figueiredo, F.B., Cuzzi, T., et al. (2004). Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998-2001). Journal of the American Veterinary Medical Association. 224(10): 9-1623. Disponível: doi: 10.2460/javma.2004.224.1623.w

Schubach, T.M.P., Oliveira, J.C. et al (2015). Diagnostic accuracy assessment of cytopathological examination of feline sporotrichosis. Med Mycol. 53(8): 4-880. https://www.arca.fiocruz.br/handle/icict/31881

Published

11/08/2022

How to Cite

PODESTÁ JUNIOR, R. L. de .; COSTA, B. E. .; SILVA, E. N. .; SANTOS, T. C. F. dos .; COSTA, L. F. .; PRADO, B. B. de P. .; SALLES, B. C. C. .; OLIVEIRA, N. de M. S. .; GARCIA, J. A. D. .; MURATORI, M. C. S. . Feline sporotrichosis: Clinical conduct, diagnosis and treatment recommended in the municipality of Vitória- ES . Research, Society and Development, [S. l.], v. 11, n. 10, p. e589111031028, 2022. DOI: 10.33448/rsd-v11i10.31028. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/31028. Acesso em: 2 oct. 2022.

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Section

Agrarian and Biological Sciences