The importance of nutrition in the treatment of polycystic ovary syndrome

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.31522

Keywords:

Polycystic ovary syndrome; Quality of life; Treatment; Benefits; Prevention; Nutritional management.

Abstract

Polycystic ovary syndrome (PCOS) is a very common disease affecting about 5% to 10% of the female population and being one of the main causes of infertility in women of reproductive age. It is characterized by hormonal disorders such as menstrual irregularity or amenorrhea, which can result in anovulation, hirsutism, acne, alopecia and obesity. The present research aimed to find out how prevention and quality of life can benefit these women with PCOS. This was a narrative review of the literature, carried out in the PUBMED, BIREME and SCIELO databases, with the descriptors “Polycystic ovarian syndrome/Polycystic ovarian syndrome”, “Polycystic ovary/polycystic ovarian syndrome”, “Nutritional treatment of PCOS / nutritional treatment of POS", “Metformin/ Metformin” and “Anticonceptional/ Contraceptive”. The results showed that lifestyle changes, physical activity and vitamin and mineral supplement intake have a positive effect on the health of women with PCOS. Thus, nutritional aspects tend to be paramount, as it helps to maintain food diversification balanced in the needs of each patient with this syndrome, and weight reduction of 5 to 10% can improve several symptoms in PCOS.

References

Arentz, S., Smith, C. A., Abbott, J., & Bensoussan, A. (2017). Nutritional supplements and herbal medicines for women with polycystic ovary syndrome; a systematic review and meta-analysis. BMC Complementary and Alternative Medicine, 17(1). https://doi.org/10.1186/s12906-017-2011-x

Arusoglu, G., Koksal, G., Cinar, N., Tapan, S., Aksoy, D. Y., & Yildiz, B. O. (2013). Basal and Meal-Stimulated Ghrelin, PYY, CCK Levels and Satiety in Lean Women With Polycystic Ovary Syndrome: Effect of Low-Dose Oral Contraceptive. The Journal of Clinical Endocrinology & Metabolism, 98(11), 4475–4482. https://doi.org/10.1210/jc.2013-1526

Azevedo, G. D. de, Costa, E. C., Micussi, M. T. A. B. C., & Sá, J. C. F. de. (2008). Modificações do estilo de vida na síndrome dos ovários policísticos: papel do exercício físico e importância da abordagem multidisciplinar. Revista Brasileira de Ginecologia E Obstetrícia, 30(5). https://doi.org/10.1590/s0100-72032008000500009

Brand-Miller, J. C., Thomas, M., Swan, V., Ahmad, Z. I., Petocz, P. & Colagiuri, S. (2003). Physiological Validation of the Concept of Glycemic Load in Lean Young Adults, The Journal of Nutrition, 133 (9), 2728–2732, https://doi.org/10.1093/jn/133.9.2728

Calixto, C. F. dos S., Paula, T. de M. D. e, Cândido, A. L., Rodrigues, A. M. dos S., Santos, L. C. dos, & Ferreira, A. V. M. (2012). Estado nutricional e consumo alimentar de pacientes portadoras de síndrome de ovários policísticos. Revista Mineira de Enfermagem, 16(2), 159–165. http://www.reme.org.br/artigo/detalhes/514#

Conitec – Comissão Nacional de Incorporação de Tecnologia do Sus. (2019). Protocolo clínico e diretrizes terapêuticas para Síndrome dos Ovários Policísticos. 1 – 171. http://conitec.gov.br/images/Consultas/2019/Relatorio_PCDT_SindromeOvariosPolicisticos_CP05_2019.pdf

Dastorani, M., Aghadavod, E., Mirhosseini, N., Foroozanfard, F., Zadeh Modarres, S., Amiri Siavashani, M., & Asemi, Z. (2018). The effects of vitamin D supplementation on metabolic profiles and gene expression of insulin and lipid metabolism in infertile polycystic ovary syndrome candidates for in vitro fertilization. Reproductive Biology and Endocrinology, 16(1). https://doi.org/10.1186/s12958-018-0413-3

Domecq, J. P., Prutsky, G., Mullan, R. J., Hazem, A., Sundaresh, V., Elamin, M. B., Phung, O. J., Wang, A., Hoeger, K., Pasquali, R., Erwin, P., Bodde, A., Montori, V. M., & Murad, M. H. (2013). Lifestyle Modification Programs in Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis. The Journal of Clinical Endocrinology & Metabolism, 98(12), 4655–4663. https://doi.org/10.1210/jc.2013-2385

Esfahanian, F., Zamani, M. M., Heshmat, R., & Moini nia, F. (2012). Effect of Metformin compared with hypocaloric diet on serum C-reactive protein level and insulin resistance in obese and overweight women with polycystic ovary syndrome. Journal of Obstetrics and Gynaecology Research, 39(4), 806–813. https://doi.org/10.1111/j.1447-0756.2012.02051.x

Gambineri, A., Pelusi, C., Vicennati, V., Pagotto, U., & Pasquali, R. (2002). Obesity and the polycystic ovary syndrome. International Journal of Obesity, 26(7), 883–896. https://doi.org/10.1038/sj.ijo.0801994

Geier, L. M., Bekx, M. T., & Connor, E. L. (2012). Factors Contributing to Initial Weight Loss Among Adolescents with Polycystic Ovary Syndrome. Journal of Pediatric and Adolescent Gynecology, 25(6), 367–370. https://doi.org/10.1016/j.jpag.2012.06.008

Gholizadeh Shamasbi, S., Dehgan, P., Mohammad-Alizadeh Charandabi, S., Aliasgarzadeh, A., & Mirghafourvand, M. (2018). The effect of resistant dextrin as a prebiotic on metabolic parameters and androgen level in women with polycystic ovarian syndrome: a randomized, triple-blind, controlled, clinical trial. European Journal of Nutrition, 58(2), 629–640. https://doi.org/10.1007/s00394-018-1648-7

Hajimonfarednejad, M., Nimrouzi, M., Heydari, M., Zarshenas, M. M., Raee, M. J., & Jahromi, B. N. (2018). Insulin resistance improvement by cinnamon powder in polycystic ovary syndrome: A randomized double-blind placebo controlled clinical trial. Phytotherapy Research : PTR, 32(2), 276–283. https://doi.org/10.1002/ptr.5970

Ibáñez, L., Oberfield, Sharon E., Witchel, S., Auchus, Richard J., Chang, R. Jeffrey, Codner, E., Dabadghao, P., Darendeliler, F., Elbarbary, N., Gambineri, A., Garcia Rudaz, C., Hoeger, Kathleen M., López-Bermejo, A., Ong, K., Peña, Alexia S., Reinehr, T., Santoro, N., Tena-Sempere, M., Tao, R., & Yildiz, Bulent O. (2017). An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence. Hormone Research in Paediatrics, 88(6), 371–395. https://doi.org/10.1159/000479371

Jamilian, M., Samimi, M., Mirhosseini, N., Afshar Ebrahimi, F., Aghadavod, E., Talaee, R., Jafarnejad, S., Hashemi Dizaji, S., & Asemi, Z. (2018). The influences of vitamin D and omega-3 co-supplementation on clinical, metabolic and genetic parameters in women with polycystic ovary syndrome. Journal of Affective Disorders, 238, 32–38. https://doi.org/10.1016/j.jad.2018.05.027

Joshipura, K. J., Hu, F. B., Manson, J. E., Stampfer, M. J., Rimm, E. B., Speizer, F. E., Colditz, G., Ascherio, A., Rosner, B., Spiegelman, D., & Willett, W. C. (2001). The Effect of Fruit and Vegetable Intake on Risk for Coronary Heart Disease. Annals of Internal Medicine, 134(12), 1106. https://doi.org/10.7326/0003-4819-134-12-200106190-00010

Legro, R. S. (2017). Evaluation and Treatment of Polycystic Ovary Syndrome (K. R. Feingold, B. Anawalt, A. Boyce, G. Chrousos, W. W. de Herder, K. Dhatariya, K. Dungan, A. Grossman, J. M. Hershman, J. Hofland, S. Kalra, G. Kaltsas, C. Koch, P. Kopp, M. Korbonits, C. S. Kovacs, W. Kuohung, B. Laferrère, E. A. McGee, & R. McLachlan, Eds.). PubMed; MDText.com, Inc. https://www.ncbi.nlm.nih.gov/books/NBK278959/#:~:text=Some%20of%20the%20most%20common

Legro, R. S., Dodson, W. C., Kris-Etherton, P. M., Kunselman, A. R., Stetter, C. M., Williams, N. I., Gnatuk, C. L., Estes, S. J., Fleming, J., Allison, K. C., Sarwer, D. B., Coutifaris, C., & Dokras, A. (2015). Randomized Controlled Trial of Preconception Interventions in Infertile Women With Polycystic Ovary Syndrome. The Journal of Clinical Endocrinology & Metabolism, 100(11), 4048–4058. https://doi.org/10.1210/jc.2015-2778

Lourdes, I., Marta, D., Cristina G. B., Rita, M., Edurne, G., Abel, L. B. & Francis, Z. (2020). Toward a Treatment Normalizing Ovulation Rate in Adolescent Girls With Polycystic Ovary Syndrome. Journal of the Endocrine Society, 4 (5) https://doi.org/10.1210/jendso/bva;;a032

Martins, W. de P., Soares, G. M., Vieira, C. S., Reis, R. M. dos, Sá, M. F. S. de, & Ferriani, R. A. (2009). Resistência à insulina em mulheres com síndrome dos ovários policísticos modifica fatores de risco cardiovascular. Revista Brasileira de Ginecologia E Obstetrícia, 31(3), 111–116. https://doi.org/10.1590/s0100-72032009000300002

Pal, L., Berry, A., Coraluzzi, L., Kustan, E., Danton, C., Shaw, J., & Taylor, H. (2012). Therapeutic implications of vitamin D and calcium in overweight women with polycystic ovary syndrome. Gynecological Endocrinology, 28(12), 965–968. https://doi.org/10.3109/09513590.2012.696753

Pereira, J. M., Silva, V. de O., & Cavalcanti, D. da S. P. (2015). Síndrome do ovário policístico: terapia medicamentosa com metformina e anticoncepcionais orais. Saúde & ciência em ação, 1(1), 26–42. https://revistas.unifan.edu.br/index.php/RevistaICS/article/view/103#:~:text=Ao%20se%20trat ar%20esta%20s%C3%ADndr

Saúde da Mulher traz informações sobre ovário policístico. (2016, November 16). Jornal Da USP. https://jornal.usp.br/radio-usp/radioagencia-usp/saude-da-mulher-traz-informacoes-sobre-ovario-policistico/

Santos, T., De Santana Batista, A., Macêdo Brandão, I., Oliveira De Carvalho, F., Martins, F., De Moura Costa, D., Augusta, C., Barassa, R., Roque, L., & Junior, G. (2019). ASPECTOS NUTRICIONAIS E MANEJO ALIMENTAR EM MULHERES COM SÍNDROME DOS OVÁRIOS POLICÍSTICOS NUTRITIONAL ASPECTS AND FOOD MANAGEMENT IN WOMEN WITH SYNDROME OF POLYCYSTIC OVARY. https://portal.unisepe.com.br/unifia/wp-content/uploads/sites/10001/2019/06/058_ASPECTOS-NUTRICIONAIS-E-MANEJO-ALIMENTAR-EM-MULHERES-COM-S%C3%8DNDROME-DOS-OV%C3%81RIOS-POLIC%C3%8DSTICOS_649_a_670.pdf

Síndrome de ovários policísticos. Revista Mineira de Enfermagem, 16(2), 159–165. http://www.reme.org.br/artigo/detalhes/514#

Sørensen, L. B., Søe, M., Halkier, K. H., Stigsby, B., & Astrup, A. (2012). Effects of increased dietary protein-to-carbohydrate ratios in women with polycystic ovary syndrome. The American Journal of Clinical Nutrition, 95(1), 39–48. https://doi.org/10.3945/ajcn.111.020693

Sousa, L. M. M., Firmino, C. F., Marques-Vieira, C. M. A., Severino, S. S. P., & Pestana, H. C. F. C. (n.d.). Reviews of the scientific literature: types, methods and applications in nursing. Core.ac.uk. https://core.ac.uk/display/232112845?utm_source=pdf&utm_medium=banner&utm_campaign=pdf-decoration-v1

Shang, Y., Zhou, H., Hu, M., & Feng, H. (2020). Effect of Diet on Insulin Resistance in Polycystic Ovary Syndrome. The Journal of Clinical Endocrinology & Metabolism, 105(10). https://doi.org/10.1210/clinem/dgaa425

Swora-Cwynar, E., Kujawska-Łuczak, M., Suliburska, J., Reguła, J., Kargulewicz, A., Kręgielska-Narożna, M., Marcinkowska, E., Kanikowska, A., Bielas, M., Grzymisławski, M., & Bogdański, P. (2016). The effects of a low-calorie diet or an isocaloric diet combined with metformin on sex hormones In obese women of child-bearing age. Acta Scientiarum Polonorum Technologia Alimentaria, 15(2), 213–220. https://doi.org/10.17306/J.AFS.2016.2.21

Walsh, C. O., Ebbeling, C. B., Swain, J. F., Markowitz, R. L., Feldman, H. A., & Ludwig, D. S. (2013). Effects of Diet Composition on Postprandial Energy Availability during Weight Loss Maintenance. PLoS ONE, 8(3), e58172. https://doi.org/10.1371/journal.pone.0058172

Published

29/06/2022

How to Cite

COUTINHO, M. E. F. .; XAVIER , M. C. .; SALOMON , A. L. R. . The importance of nutrition in the treatment of polycystic ovary syndrome . Research, Society and Development, [S. l.], v. 11, n. 8, p. e56511831522, 2022. DOI: 10.33448/rsd-v11i8.31522. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/31522. Acesso em: 14 jul. 2024.

Issue

Section

Health Sciences