Piceatannol: a natural stilbene with a broad spectrum of biological activities





Estilbene; Resveratrol; Piceatannol; Biological activits


Piceatannol (trans-3,3,4,5-tetrahydroxystilbene) is a structural analogue related to resveratrol, belonging to the stilbene group. It is found in natural sources such as almonds, peanuts, teas, berries, and passion fruit, but mainly in grapes and in the seeds of passion fruits. Studies have shown a range of health-promoting biological properties for piceatannol, with emphasis for antioxidant, anti-inflammatory, and anticancer potential. Although resveratrol has been the stilbene most known and studied, studies have shown that piceatannol is found in higher amounts than resveratrol in several natural plant sources, and, in addition, due to the presence of the additional hydroxyl group in the 3' position in its structure, has shown some biological activities superior to those of resveratrol. In view of this, in this study a systematic literature review was carried out on the main chemical characteristics, natural sources and biological properties of piceatannol. Thus, this study will contribute and encourage the dissemination of knowledge and development of new studies about this natural compound potentially useful for human health.


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How to Cite

ZOMER, A. P. L.; RODRIGUES, C. A. .; MALDANER, L. Piceatannol: a natural stilbene with a broad spectrum of biological activities. Research, Society and Development, [S. l.], v. 11, n. 9, p. e49211932221, 2022. DOI: 10.33448/rsd-v11i9.32221. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32221. Acesso em: 19 aug. 2022.



Exact and Earth Sciences