Complications in patients with COVID-19 in a cohort of intensive care hospitalists

Authors

DOI:

https://doi.org/10.33448/rsd-v11i11.32451

Keywords:

COVID-19; Intensive Care Unit; SARS-CoV-2.

Abstract

This article aims to identify the complications presented in patients with COVID-19 during their stay in intensive care. We conducted a retrospective documentary cohort study in medical records of adults admitted to an Intensive Care Unit designated for the treatment of COVID-19 patients, from September 2020 to January 2021. The sample consisted of 47 medical records of patients over 18 years old, with confirmed diagnosis for SARS-COV-219 by reverse transcription test and polymerase chain reaction. Medical records of 24 women (51,1%) and 23 men (49,9%) were included in the study, with an average of 70 years old. The main complications described involved the blood, immune and respiratory systems. Electrolyte disorder was the most frequent complication observed in 100% of the patients, followed by leukocytosis (95,7%), acid-base disorder and acute respiratory failure, present in 87,2% of the analysed cases. We conclude that COVID-19 causes damage to multiple systems, directly affecting the prognosis of patients.

References

Bechmann, N., Barthel, A., Schedl, A., Herzig, S., Varga, Z., Gebhard, C., Mayr, M., Hantel, C., Beuschlein, F., Wolfrum, C., Perakakis, N., Poston, L., Andoniadou, C. L., Siow, R., Gainetdinov, R. R., Dotan, A., Shoenfeld, Y., Mingrone, G., & Bornstein, S. R. (2022). Sexual dimorphism in COVID-19: potential clinical and public health implications. The Lancet Diabetes & Endocrinology, 10(3), 221–230.

Bhatraju, P. K., Ghassemieh, B. J., Nichols, M., Kim, R., Jerome, K. R., Nalla, A. K., Greninger, A. L., Pipavath, S., Wurfel, M. M., Evans, L., Kritek, P. A., West, T. E., Luks, A., Gerbino, A., Dale, C. R., Goldman, J. D., O’Mahony, S., & Mikacenic, C. (2020). Covid-19 in critically ill patients in the seattle region—Case series. New England Journal of Medicine, 382(21), 2012–2022.

Chen, T., Wu, D., Chen, H., Yan, W., Yang, D., Chen, G., Ma, K., Xu, D., Yu, H., Wang, H., Wang, T., Guo, W., Chen, J., Ding, C., Zhang, X., Huang, J., Han, M., Li, S., Luo, X., & Zhao, J. (2020). Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ, 368, m1091.

Chow, N., Fleming-Dutra, K., Gierke, R., Hall, A., Hughes, M., Pilishvili, T., Ritchey, M., Roguski, K., Skoff, T., & Ussery, E. (2020). Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 — United States, February 12–March 28, 2020. MMWR. Morbidity and Mortality Weekly Report, 69(13).

Gentile, S., Strollo, F., & Ceriello, A. (2020). COVID-19 infection in Italian people with diabetes: Lessons learned for our future (An experience to be used). Diabetes Research and Clinical Practice, 162, 108137.

Grasselli, G., Zangrillo, A., Zanella, A., Antonelli, M., Cabrini, L., Castelli, A., Cereda, D., Coluccello, A., Foti, G., Fumagalli, R., Iotti, G., Latronico, N., Lorini, L., Merler, S., Natalini, G., Piatti, A., Ranieri, M. V., Scandroglio, A. M., Storti, E., & Cecconi, M. (2020). Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA, 323(16).

Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., Liu, L., Shan, H., Lei, C., Hui, D. S. C., Du, B., Li, L., Zeng, G., Yuen, K.-Y., Chen, R., Tang, C., Wang, T., Chen, P., Xiang, J., & Li, S. (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine, 382(18).

Hu, B., Guo, H., Zhou, P., & Shi, Z.-L. (2021). Characteristics of sars-cov-2 and covid-19. Nature Reviews Microbiology, 19(3), 141–154.

Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., Cheng, Z., Yu, T., Xia, J., Wei, Y., Wu, W., Xie, X., Yin, W., Li, H., Liu, M., & Xiao, Y. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223), 497–506.

Hur, K., Price, C. P. E., Gray, E. L., Gulati, R. K., Maksimoski, M., Racette, S. D., Schneider, A. L., & Khanwalkar, A. R. (2020). Factors associated with intubation and prolonged intubation in hospitalized patients with covid-19. Otolaryngology–Head and Neck Surgery, 163(1), 170–178.

King, C. S., Sahjwani, D., Brown, A. W., Feroz, S., Cameron, P., Osborn, E., Desai, M., Djurkovic, S., Kasarabada, A., Hinerman, R., Lantry, J., Shlobin, O. A., Ahmad, K., Khangoora, V., Aryal, S., Collins, A. C., Speir, A., & Nathan, S. (2020). Outcomes of mechanically ventilated patients with COVID-19 associated respiratory failure. PLOS ONE, 15(11), e0242651.

Kumar, A., Arora, A., Sharma, P., Anikhindi, S. A., Bansal, N., Singla, V., Khare, S., & Srivastava, A. (2020). Is diabetes mellitus associated with mortality and severity of COVID-19? A meta-analysis. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(4), 535–545.

Liao, D., Zhou, F., Luo, L., Xu, M., Wang, H., Xia, J., Gao, Y., Cai, L., Wang, Z., Yin, P., Wang, Y., Tang, L., Deng, J., Mei, H., & Hu, Y. (2020). Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: A retrospective cohort study. The Lancet Haematology, 7(9), e671–e678.

Lippi, G., South, A. M., & Henry, B. M. (2020). Electrolyte imbalances in patients with severe coronavirus disease 2019 (COVID-19). Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 57(3), 262–265.

Nechipurenko, Y. D., Semyonov, D. A., Lavrinenko, I. A., Lagutkin, D. A., Generalov, E. A., Zaitceva, A. Y., Matveeva, O. V., & Yegorov, Y. E. (2021). The role of acidosis in the pathogenesis of severe forms of covid-19. Biology, 10(9), 852.

Our World in Data. (2022). Coronavirus (COVID-19) Deaths - Statistics and Research. Our World in Data. https://ourworldindata.org/covid-deaths

Ritchie, H., Mathieu, E., Rodés-Guirao, L., Appel, C., Giattino, C., Ortiz-Ospina, E., Hasell, J., Macdonald, B., Beltekian, D., & Roser, M. (2022). Coronavirus pandemic(COVID-19). Our World in Data. https://ourworldindata.org/coronavirus/country/brazil

Sommer, P., Lukovic, E., Fagley, E., Long, D. R., Sobol, J. B., Heller, K., Moitra, V. K., Pauldine, R., O’Connor, M. F., Shahul, S., Nunnally, M. E., & Tung, A. (2020). Initial clinical impressions of the critical care of covid-19 patients in seattle, new york city, and chicago. Anesthesia & Analgesia, 131(1), 55–60.

The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team (2020). The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) - China, 2020. China CDC Weekly, 2(8), 113–122.

Toassi, R. F. C., & Petry, P. C. (2021). Metodologia científica aplicada à área da Saúde (2 a ed.): Editora da UFRGS.

Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., Zhao, Y., Li, Y., Wang, X., & Peng, Z. (2020). Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in wuhan, china. JAMA, 323(11), 1061.

Xiong, T.-Y., Redwood, S., Prendergast, B., & Chen, M. (2020). Coronaviruses and the cardiovascular system: Acute and long-term implications. European Heart Journal, 41(19), 1798–1800.

Young, B. E., Ong, S. W. X., Kalimuddin, S., Low, J. G., Tan, S. Y., Loh, J., Ng, O.-T., Marimuthu, K., Ang, L. W., Mak, T. M., Lau, S. K., Anderson, D. E., Chan, K. S., Tan, T. Y., Ng, T. Y., Cui, L., Said, Z., Kurupatham, L., Chen, M. I.-C., & Chan, M. (2020). Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA, 323(15), 1488.

Zarychanski, R., & Houston, D. S. (2017). Assessing thrombocytopenia in the intensive care unit: The past, present, and future. Hematology, 2017(1), 660–666.

Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Xiang, J., Wang, Y., Song, B., Gu, X., Guan, L., Wei, Y., Li, H., Wu, X., Xu, J., Tu, S., Zhang, Y., Chen, H., & Cao, B. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. The Lancet, 395(10229), 1054–1062.

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Published

15/08/2022

How to Cite

SOUZA, N. J. R. .; COELHO, V. L. .; LIMA, W. H. C. B. .; PINHEIRO, J. D. . Complications in patients with COVID-19 in a cohort of intensive care hospitalists. Research, Society and Development, [S. l.], v. 11, n. 11, p. e40111132451, 2022. DOI: 10.33448/rsd-v11i11.32451. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32451. Acesso em: 22 nov. 2024.

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Section

Health Sciences