Profile of gestational and congenital toxoplasmosis in a city in western Paraná
DOI:
https://doi.org/10.33448/rsd-v11i11.33456Keywords:
Toxoplasmosis; Pregnancy; Congenital toxoplasmosis.Abstract
Toxoplasmosis is a parasitic disease that, when acquired during pregnancy can be transmitted to the fetus, being asymptomatic, causing sequelae to the newborn or leading to fetal death. Thus, this retrospective, quantitative and observational work analyzed data from pregnant women diagnosed with toxoplasmosis, in outpatient care during the years 2015 to 2019, in the city of Cascavel-PR. This study sought to analyze the efficiency of the drugs (Spiramycin, Pyrimethamine, Sulfadiazine and Folinic Acid), establish the result of the newborns' serology, in addition to obtain sociodemographic data of these pregnant women, analyzing age, marital status and education level. Fisher’s statistical test was used, with a significance level of α <0,05. In this study, pregnant women who did not use medication had 8.63 times the chance (p <0,01) of an unfavorable outcome compared to those who underwent complete treatment. Therefore, the importance of performing early prenatal care and performing the correct treatment for gestational Toxoplasmosis is highlighted.
References
Avelar, J. B. (2013). Toxoplasmose crônica em gestantes. Avaliação da prevalência, fatores de risco e acompanhamento de um grupo de recém-nascidos em Goiânia – Goiás [Universidade Federal de Goiás]. https://repositorio.bc.ufg.br/tede/handle/tede/3483
Avelino, M. M., & Amaral, W. N. (2008). Transmissão Vertical, Infecções Congênitas (1 ed). Contato Comunicação.
Avelino, M. M., Campos Júnior, D., Parada, J. B. de, & Castro, A. M. de. (2004). Risk factors for Toxoplasma gondii infection in women of childbearing age. Brazilian Journal of Infectious Diseases, 8(2). https://doi.org/10.1590/S1413-86702004000200007
Beck, S. T., Konopka, C. K., Diehl, F. P., & Silva, A. K. da. (2011). Importância do rastreamento sorológico da toxoplasmose em gestantes atendidas em ambulatório de pré-natal de alto risco. Saúde (Santa Maria), 36(1), 29. https://doi.org/10.5902/223658342007
Bittencourt, L. H. F. de B., Lopes-Mori, F. M. R., Mitsuka-Breganó, R., Valentim-Zabott, M., Freire, R. L., Pinto, S. B., & Navarro, I. T. (2012). Soroepidemiologia da toxoplasmose em gestantes a partir da implantação do programa de vigilância da toxoplasmose adquirida e congênita emmunicípios da região oeste do Paraná. Revista Brasileira de Ginecologia e Obstetricia, 34(2), 63–68.
Febrasgo. (2018). Toxoplasmose e Gravidez. http://www.febrasgo.org.br/pt/
Figueiró-Filho, E. A., Lopes, A. H. A., Senefonte, F. R. de A., Souza Júnior, V. G. de, Botelho, C. A., Figueiredo, M. S., & Duarte, G. (2005). Toxoplasmose aguda: estudo da freqüência, taxa de transmissão vertical e relação entre os testes diagnósticos materno-fetais em gestantes em estado da Região Centro-Oeste do Brasil. Revista Brasileira de Ginecologia e Obstetrícia, 27(8). https://doi.org/10.1590/S0100-72032005000800002
Isabel, T. F., Costa, P. I. da, & Simões, M. J. S. (2007). Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English]. Scientia Medica, 17(2), 57–62. http://revistaseletronicas.pucrs.br/ojs/index.php/scientiamedica/article/view/1636
Joiner, K. A., & Dubremetz, J. F. (1993). Toxoplasma gondii: a protozoan for the nineties. Infection and Immunity, 61(4), 1169–1172. https://doi.org/10.1128/iai.61.4.1169-1172.1993
Martins, C. (2002). Toxoplasmose na gravidez. Revista Portuguesa de Clínica Geral, 18, 333–340.
Ministério da Saúde. (2020). Nota Técnica Ministério da Saúde. No14/2020COSMU/ CGCIVI/DAPES/SAPS/MS.
Montenegro, C. A. B., & Rezende Filho, J. (2016). Rezende Obstetrícia (13a ed.). Guanabara Koogan.
Montoya, J., & Liesenfeld, O. (2004). Toxoplasmosis. The Lancet, 363(9425), 1965–1976. https://doi.org/10.1016/S0140-6736(04)16412-X
Pessanha, T. M., Carvalho, M. de, Pone, M. V. S., & Gomes Júnior, S. C. (2011). Abordagem diagnóstica e terapêutica da toxoplasmose em gestantes e as repercussões no recém-nascido. Revista Paulista de Pediatria, 29(3), 341–347. https://doi.org/10.1590/S0103-05822011000300006
Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Santa Maria/RS. Ed. UAB/NTE/UFSM.
Petersen, E., & Mandelbrot, L. (2020). Toxoplasmosis and pregnancy. UpToDate.
Peyron, F., Wallon, M., Liou, C., & Garner, P. (1999). Treatments for toxoplasmosis in pregnancy. Cochrane Database of Systematic Reviews, 2010(1). https://doi.org/10.1002/14651858.CD001684
Picone, O., Fuchs, F., Benoist, G., Binquet, C., Kieffer, F., Wallon, M., Wehbe, K., Mandelbrot, L., & Villena, I. (2020). Toxoplasmosis screening during pregnancy in France: Opinion of an expert panel for the CNGOF. Journal of Gynecology Obstetrics and Human Reproduction, 49(7), 101814. https://doi.org/10.1016/j.jogoh.2020.101814
Remington, J. S., Thulliez, P., & Montoya, J. G. (2004). Recent Developments for Diagnosis of Toxoplasmosis. Journal of Clinical Microbiology, 42(3), 941–945. https://doi.org/10.1128/JCM.42.3.941-945.2004
Sartori, A. L., Minamisava, R., Avelino, M. M., & Martins, C. A. (2011). Triagem pré-natal para toxoplasmose e fatores associados à soropositividade de gestantes em Goiânia, Goiás. Revista Brasileira de Ginecologia e Obstetrícia, 33(2), 93–98. https://doi.org/10.1590/S0100-72032011000200007
Spalding, S. M., Amendoeira, M. R. R., Klein, C. H., & Ribeiro, L. C. (2005). Serological screening and toxoplasmosis exposure factors among pregnant women in South of Brazil. Revista Da Sociedade Brasileira de Medicina Tropical, 38(2), 173–177. https://doi.org/10.1590/S0037-86822005000200009
Valadão, M. C., Zancan, A., Flores, F. V., Ramos, L., Farinha, L. B., Cavalheiro, C. V., Schallenberger, V., Silva, C. R., & Menegolla, I. A. (2018). Toxoplasmose Congênita: características clínico-epidemiológicas dos recémnascidos no surto de toxoplasmose em Santa Maria/RS, 2018. IV Simpósio Brasileiro de Toxoplasmose.
Varella, I. S., Wagner, M. B., Darela, A. C., Nunes, L. M., & Müller, R. W. (2003). Prevalência de soropositividade para toxoplasmose em gestantes. Jornal de Pediatria, 79(1), 69–74. https://doi.org/10.1590/S0021-75572003000100012
Vaz, R. S. (2006). Diagnóstico sorológico, isolamento e caracterização molecular de toxoplasma gondii em mulheres gestantes atendidas pelo serviço público na cidade de Curitiba [Universidade Federal do Paraná]. https://acervodigital.ufpr.br/handle/1884/22163
Wallon, M., Liou, C., Garner, P., & Peyron, F. (1999). Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy. BMJ, 318(7197), 1511–1514. https://doi.org/10.1136/bmj.318.7197.1511
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Cecilia Mello Lucena; Winny Hirome Takahashi Yonegura; Odirlei Magnagnagno
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.