Home dental service in child with chromosome 9 trisomy – mosaic type: case report

Authors

DOI:

https://doi.org/10.33448/rsd-v11i11.33608

Keywords:

Chromosomes, Human, Pair 9; Trisomy; Mosaicism; Dental care for disabled; Case reports.

Abstract

The Chromosome 9, Trisomy mosaic (T9M) is a rare multisystemic disorder with broad clinical phenotype, vast individual variability, increased risk of prenatal and perinatal problems, and associated with advanced parental age. The main discoveries are craniofacial dysmorphisms, multiple organ malformations, and neurological and psychomotor development delay. The goal is reporting general and buccal characteristics, as well as the home care dental treatment in a child with T9M. Child at 2 years and 6 months old, female, with home dental service during the pandemic, because the mother reported that the child was restless. The patient uses nasogastric tube and had recent introduction of liquid food, with anti-reflux valve. During the clinical examination, we diagnosed generalized gingivitis, presence of reddish area on palate and rash hematoma in the 54. The orientation given to mother and helpers was to make hygiene with fluoridated toothpaste, individualizing the technics: single tufted toothbrush for molars, flossing with teeth floss rod, using tongue scraper, and using mouth opener made out of popsicle sticks. For Candidiasis treatment, a topical antifungal (VASA solution) was used for three weeks, which caused wound remission. The dental home service for treating T9M requires humanized perspective and early childhood care, which improves the quality of life.

References

Amaral, N. N., Cunha, M. C. B., Labrocini, R. H. D. D., Oliveira, A. S. B., & Gabbai, A. A. (2001). Assistência domiciliar à saúde (Home Health Care): sua história e sua relevância para o sistema de saúde atual. Rev Neurociências, 9(3), 111-7.

Arvelo, E., Armas, J., & Guillen, M. (2020). Assessing the distribution of elderly requiring care: a case study on the residents in Barcelona and the impact of COVID-19. Int J Environ Res Public Health, 17(20), 7486.

Bruns, D. (2011). Presenting physical characteristics, medical conditions, and developmental status of long-term survivors with trisomy 9 mosaicism. American Journal Of Medical Genetics Part A, 155A, 1033–1039.

Bruns, D. A., & Campbell, E. (2015). Twenty-five additional cases of trisomy 9 mosaic: Birth information, medical conditions, and developmental status. American Journal Of Medical Genetics Part A, 167, 997– 1007.

Chen, C.-P., Hung, F.-Y., Su, Y.-N., Chern, S.-R., Su, J.-W., Lee, C.-C., Chen, Y.-T., Chen, W.-L., & Wang, W. (2011). Prenatal diagnosis of mosaic trisomy 9. Taiwanese Journal of Obstetrics & Gynecology, 50, 549–553.

Chen, C., Lin, H., Su, Y., Chern, S., Tsai, F., Wu, P., Lee, C., Chen, Y., Lee, M., Pan, C., & Wang, W. (2010). Mosaic trisomy 9 at amniocentesis: Prenatal diagnosis and molecular genetic analyses. Taiwanese Journal of Obstetrics & Gynecology. 49, 341–350.

Dos Santos, M.T., & Nogueira, M.L. (2005). Infantile reflexes and their effects on dental caries and oral hygiene in cerebral palsy individuals. J Oral Rehab, 32, 880-885.

Ferreres, J. C., Planas, S., Martínez-Sáez, E. A., Vendrell, T., Peg, V., Salcedo, M. T., Cajal, S. R., & Torán, N. (2008). Pathological findings in the complete trisomy 9 syndrome: three case reports and review of the literature. Pediatric and Developmental Pathology, 11(1), 23-29.

Franco, J. B., Camargo, A. R., & Peres, M. P. S. M. (2020). Cuidados Odontológicos na era do COVID-19: recomendações para procedimentos odontológicos e profissionais. Rev Assoc Paul Cir Dent., 74(1), 18-21.

Gomes, G. E., Barbosa, R. R., Paula, F. W. G., Torres, C. P., & Queiroz, A. M. (2006). Tratamento odontológico em paciente com trissomia do cromossomo 9: relato de caso. Revista da Faculdade de Odontologia-UPF, 11(2).

Hegde, A. M., Shetty, Y. R., & Pani, S.C. (2008). Drooling of saliva and its effect on the oral health status of children with cerebral palsy. J Clin Pediatr Dent, 32, 235-238.

Jimenez, J. L., Domínguez, R., GimenezPrats, M. J., & Chilenos-Kutsner, E. (2001). Characteristics and dental treatment of partial of trisomy 9. Med Oral, 6, 290-5.

Karataban, P. K. (2022). Oral Aspects and Dental Management of Special Needs Patient. In: Ardelean, L., & Rusu L. C. (Eds.). Oral Health Care - An Important Issue of the Modern Society. IntechOpen. doi: 10.5772/intechopen.101067

Miryounesi, M., Dianatpour, M., Shadmani, Z., & Ghafouri-Fard, S. (2016). Report of a Case with Trisomy 9 Mosaicism. Iran J Med Sci, 41(3), 249-252.

Mukherjee P. K., Chen H., Patton L. L., Evans S., Lee A., Kumwenda J., Hakim J., Masheto G., Sawe F., Pho M. T., Freedberg K. A., Shiboski C. H., Ghannoum M. A., & Salata R. A. (2017). Topical gentian violet compared with nystatin oral suspension for the treatment of oropharyngeal candidiasis in HIV-1-infected participants. AIDS, 31(1), 81-88. doi: 10.1097/QAD.0000000000001286

Murta, C. G. V., & Vargas, P. R. M. (2001). Trisomy 9 with increased nuchal translucency: ultrasound and pathologic correlation - a case report. Radiol Bras, 34, 105-8.

Littooij, A. S., Hochstenbach, R., Sinke, R. J., Tintelen, P., & Giltay. J.C. (2002). Two cases with partial trisomy 9p: molecular cytogenetic characterization and clinical follow-up. Am J Genet, 109, 125-32.

Okumura, A., Hayakawa, F., Kato, T., Kuno, K., & Watanabe K. (2000). Two patients with trisomy 9 mosaicism. Ped Int, 42, 89-91.

Patil, S. J., Ponnala, R., Shah, S., & Dalal, A. (2012). Mosaic trisomy 9 presenting with congenital heart disease, facial dysmorphism and pigmentary skin lesions: Intricate issues of genetic counseling. Indian Journal of Pediatrics, 79, 806–9.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica [e-book]. Santa Maria. Ed UAB/NTE/UFSM. Acesso em 14 agosto 2022. Disponível em: https://repositorio. ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica. pdf.

Pienaar, E. D., Young, T., & Holmes, H. (2010). Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children. Cochrane Database Syst Rev, 11, CD003940.

Reichart, P. A., Samaranayake, L. P., & Philipsen, H. P. (2000) Pathology and clinical correlates in oral candidiasis and its variants: a review. Oral Diseases, 6, 85-91.

Rio, M., Molinari, F., Heuertz, S., Ozilou, C., Gosse, P., Raul, O., Cormier Daire, V., Amiel, J., Lyonnet, S., Le Merrer, M., Turleau, C., de Blois, M. C., Prieur, M., Romana, S., Vekemans, M., Munnich, U., & Coleux L. (2002). Automated fluorescent genotyping detects 10% of cryptic subtelomeric rearrangements in idiopathic syndromic mental retardation. J Med Genet 39, 266-70

Yamagushi, A. M., Tanigushi, K. T. H., Andrade, L., Bricola, S. A. P. C., Filho, W. J., & Martins, M. A. (2010). Assitência Domiciliar: Uma proposta interdisciplinar. Barueri: Manole.

Zen, P. R., Rosa, R. F., Rosa, R. C., Graziadio, C., Paskulin, G. A. (2011). New report of two patients with mosaic trisomy 9 presenting unusual features and longer survival. Sao Paulo Med J., 129, 428-32.

Published

25/08/2022

How to Cite

LEMOS, C. A. A. .; GUARÉ, R. de O. . Home dental service in child with chromosome 9 trisomy – mosaic type: case report . Research, Society and Development, [S. l.], v. 11, n. 11, p. e368111133608, 2022. DOI: 10.33448/rsd-v11i11.33608. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/33608. Acesso em: 20 dec. 2024.

Issue

Section

Health Sciences