Oral manifestations in patients with Diabetes mellitus
DOI:
https://doi.org/10.33448/rsd-v11i12.34330Keywords:
Diabetes Mellitus; Oral Complications; Periodontal disease; Xerostomia.Abstract
The term “Diabetes mellitus” is used to identify a group of disorders characterized by elevated blood glucose levels. This elevation is the result of a deficiency in insulin secretion or an increase in cellular resistance to the actions of insulin, leading to a variety of metabolic abnormalities involving carbohydrates, fats, and proteins. Given the above, this study aimed to review the literature on local anesthetics used in dentistry, highlighting necessary information regarding the choice and amount of anesthetic, preventing the occurrence of complications. For the construction of this work, a bibliographic survey was carried out in the databases SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect, using the Mendeley reference manager. The main oral manifestations and complications related to Diabetes Mellitus involve xerostomia, dysgeusia, oral infections, dental caries and periodontal diseases. There are also reports of lesions in the oral mucosa, such as stomatitis, geographic tongue, benign migratory glossitis, fissured tongue, traumatic ulcer, lichen planus, oral lichenoid reaction and angular cheilitis. The prevalence and susceptibility of developing these lesions is higher in patients with DM compared to controls. Diabetes Mellitus is a chronic, non-communicable and endemic disease, which results in multiple complications, which increase when the patient's glycemic control is inadequate. Thus, physicians and dentists must be aware of the various oral manifestations of diabetes to make an early diagnosis.
References
Al-Maskari, Masoud Y., & Salem Al-Sudairy. 2011. “Oral Manifestations and Complications of Diabetes Mellitus: A Review.” Sultan Qaboos University Medical Journal 11(2):179–86.
Choudhury, A. A., & V. Devi Rajeswari. 2021. “Gestational Diabetes Mellitus - A Metabolic and Reproductive Disorder.” Biomedicine & Pharmacotherapy 143:112183.
Cicmil, S., Irena, M., Jelena Krunić, D. I., & Nikola, S. 2018. “Oral Alterations in Diabetes Mellitus.” Balkan Journal of Dental Medicine 22(1):7–14.
Gaede, P., Henrik, Lund-Andersen, Hans-Henrik, P., & Oluf Pedersen. 2008. “Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes.” The New England Journal of Medicine 358(6):580–91.
Herman, W. H., Thomas, J. H., Michael Brandle, K. H., Stephen Sorensen, P. Z., Richard F. H., Ronald, T. A., Michael, M. E., & Robert, E. R. 2005. “The Cost-Effectiveness of Lifestyle Modification or Metformin in Preventing Type 2 Diabetes in Adults with Impaired Glucose Tolerance.” Annals of Internal Medicine 142(5):323–32.
Holman, R. R., Sanjoy, K., Paul, M., Angelyn Bethel, David, R. M., & H. Andrew W. Neil. 2008. “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes.” The New England Journal of Medicine 359(15):1577–89.
Kim, D. L., Sun, D. K., Suk, K. K., Sooyoun, P., & Kee Ho Song. 2016. “Is an Oral Glucose Tolerance Test Still Valid for Diagnosing Diabetes Mellitus?” Diabetes & Metabolism Journal 40(2):118–28.
Lamster, I. B., Evanthia, L., Wenche, S. B., & George, W. T. 2008. “The Relationship Between Oral Health and Diabetes Mellitus.” The Journal of the American Dental Association 139:19S-24S.
Lima, S. M. F., D. C., Grisi, E. M., Kogawa, O. L., Franco, V. C., Peixoto, J. F., Gonçalves-Júnior, M. P. A., & T. M. B. Rezende. 2013. “Diabetes Mellitus and Inflammatory Pulpal and Periapical Disease: A Review.” International Endodontic Journal 46(8):700–709.
Mauri-Obradors, E. A., Estrugo-Devesa, E. Jané-Salas, M. V., & J. López-López. 2017. “Oral Manifestations of Diabetes Mellitus. A Systematic Review.” Medicina Oral, Patologia Oral y Cirugia Bucal 22(5):e586–94.
Murphy-Chutorian, B., George Han, & Steven R. Cohen. 2013. “Dermatologic Manifestations of Diabetes Mellitus: A Review.” Endocrinology and Metabolism Clinics of North America 42(4):869–98.
Nassar, M., Ahmed Daoud, Nso Nso, Luis Medina, Victoria Ghernautan, Harangad Bhangoo, Andrew Nyein, Mahmoud Mohamed, Ahmed Alqassieh, Karim Soliman, Mostafa Alfishawy, Issac Sachmechi, & Anoop Misra. 2021. “Diabetes Mellitus and COVID-19: Review Article.” Diabetes & Metabolic Syndrome: Clinical Research & Reviews 15(6):102268.
Prado, B. N., & Vaccarezza, G. F. 2017. “Alterações Bucais Em Pacientes Diabéticos.” Revista de Odontologia Da Universidade Cidade de São Paulo 25(2):147.
Rizzo, M. R., Di Meo, I., Polito, R., Auriemma, M. C., Gambardella, A., di Mauro, G., Capuano, A., & Paolisso, G. 2022. “Cognitive Impairment and Type 2 Diabetes Mellitus: Focus of SGLT2 Inhibitors Treatment.” Pharmacological Research 176:106062.
Rodrigues, C. F., Rodrigues, M. E., & Henriques, M. 2019. “Candida Sp. Infections in Patients with Diabetes Mellitus.” Journal of Clinical Medicine 8(1).
Rohani, B. 2019. “Oral Manifestations in Patients with Diabetes Mellitus.” World Journal of Diabetes 10(9):485–89.
Saghiri, M. A., Tang, C. K., & Nath, D. 2021. “Downstream Effects from Diabetes Mellitus Affected on Various Tooth Tissues: A Mini Review: Effects of Diabetes on Tooth Structure.” Dentistry Review 1(1):100002.
Segura-Egea, J. J., L. Castellanos-Cosano, G., Machuca, J., López-López, J., Martín-González, E., Velasco-Ortega, B., Sánchez-Domínguez, & F. J. López-Frías. 2012. “Diabetes Mellitus, Periapical Inflammation and Endodontic Treatment Outcome.” Medicina Oral, Patologia Oral y Cirugia Bucal 17(2):e356–61.
Taboza, Z. A., Costa, K. L., Silveira, V. R., Furlaneto, F. A., Montenegro, R. Jr., Russell, S., Dasanayake, A., & Rodrigo, O. R. 2018. “Periodontitis, Edentulism and Glycemic Control in Patients with Type 2 Diabetes: A Cross-Sectional Study.” BMJ Open Diabetes Research & Care 6(1):e000453.
Viellas, E. F. V., Domingues, R. M. S. Madeira., Dias, A. B. D., & Costa, J. V. 2013. “Manifestações Bucais Em Pacientes Portadores de Diabetes Mellitus: Uma Revisão Sistemática Oral Manifestations in Patients with Diabetes Mellitus: A Systematic Review.” Rev Odontol UNESP 42(3):211–20.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Jefferson Douglas Lima Fernandes ; Rafael Meneses Bomfim; Caroline Reis França ; Grace Kelly Martins Carneiro ; Ana Carolina Resende da Silva; Edvaldo Vieira do Nascimento Neto ; Müller Gomes dos Santos; Genilson Campos da Silva; Esther Chrystyane Costa Cabral ; Ana Lethícia Leão Santos
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.