Oral manifestations in patients with Diabetes mellitus

Authors

DOI:

https://doi.org/10.33448/rsd-v11i12.34330

Keywords:

Diabetes Mellitus; Oral Complications; Periodontal disease; Xerostomia.

Abstract

The term “Diabetes mellitus” is used to identify a group of disorders characterized by elevated blood glucose levels. This elevation is the result of a deficiency in insulin secretion or an increase in cellular resistance to the actions of insulin, leading to a variety of metabolic abnormalities involving carbohydrates, fats, and proteins. Given the above, this study aimed to review the literature on local anesthetics used in dentistry, highlighting necessary information regarding the choice and amount of anesthetic, preventing the occurrence of complications. For the construction of this work, a bibliographic survey was carried out in the databases SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect, using the Mendeley reference manager. The main oral manifestations and complications related to Diabetes Mellitus involve xerostomia, dysgeusia, oral infections, dental caries and periodontal diseases. There are also reports of lesions in the oral mucosa, such as stomatitis, geographic tongue, benign migratory glossitis, fissured tongue, traumatic ulcer, lichen planus, oral lichenoid reaction and angular cheilitis. The prevalence and susceptibility of developing these lesions is higher in patients with DM compared to controls. Diabetes Mellitus is a chronic, non-communicable and endemic disease, which results in multiple complications, which increase when the patient's glycemic control is inadequate. Thus, physicians and dentists must be aware of the various oral manifestations of diabetes to make an early diagnosis.

References

Al-Maskari, Masoud Y., & Salem Al-Sudairy. 2011. “Oral Manifestations and Complications of Diabetes Mellitus: A Review.” Sultan Qaboos University Medical Journal 11(2):179–86.

Choudhury, A. A., & V. Devi Rajeswari. 2021. “Gestational Diabetes Mellitus - A Metabolic and Reproductive Disorder.” Biomedicine & Pharmacotherapy 143:112183.

Cicmil, S., Irena, M., Jelena Krunić, D. I., & Nikola, S. 2018. “Oral Alterations in Diabetes Mellitus.” Balkan Journal of Dental Medicine 22(1):7–14.

Gaede, P., Henrik, Lund-Andersen, Hans-Henrik, P., & Oluf Pedersen. 2008. “Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes.” The New England Journal of Medicine 358(6):580–91.

Herman, W. H., Thomas, J. H., Michael Brandle, K. H., Stephen Sorensen, P. Z., Richard F. H., Ronald, T. A., Michael, M. E., & Robert, E. R. 2005. “The Cost-Effectiveness of Lifestyle Modification or Metformin in Preventing Type 2 Diabetes in Adults with Impaired Glucose Tolerance.” Annals of Internal Medicine 142(5):323–32.

Holman, R. R., Sanjoy, K., Paul, M., Angelyn Bethel, David, R. M., & H. Andrew W. Neil. 2008. “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes.” The New England Journal of Medicine 359(15):1577–89.

Kim, D. L., Sun, D. K., Suk, K. K., Sooyoun, P., & Kee Ho Song. 2016. “Is an Oral Glucose Tolerance Test Still Valid for Diagnosing Diabetes Mellitus?” Diabetes & Metabolism Journal 40(2):118–28.

Lamster, I. B., Evanthia, L., Wenche, S. B., & George, W. T. 2008. “The Relationship Between Oral Health and Diabetes Mellitus.” The Journal of the American Dental Association 139:19S-24S.

Lima, S. M. F., D. C., Grisi, E. M., Kogawa, O. L., Franco, V. C., Peixoto, J. F., Gonçalves-Júnior, M. P. A., & T. M. B. Rezende. 2013. “Diabetes Mellitus and Inflammatory Pulpal and Periapical Disease: A Review.” International Endodontic Journal 46(8):700–709.

Mauri-Obradors, E. A., Estrugo-Devesa, E. Jané-Salas, M. V., & J. López-López. 2017. “Oral Manifestations of Diabetes Mellitus. A Systematic Review.” Medicina Oral, Patologia Oral y Cirugia Bucal 22(5):e586–94.

Murphy-Chutorian, B., George Han, & Steven R. Cohen. 2013. “Dermatologic Manifestations of Diabetes Mellitus: A Review.” Endocrinology and Metabolism Clinics of North America 42(4):869–98.

Nassar, M., Ahmed Daoud, Nso Nso, Luis Medina, Victoria Ghernautan, Harangad Bhangoo, Andrew Nyein, Mahmoud Mohamed, Ahmed Alqassieh, Karim Soliman, Mostafa Alfishawy, Issac Sachmechi, & Anoop Misra. 2021. “Diabetes Mellitus and COVID-19: Review Article.” Diabetes & Metabolic Syndrome: Clinical Research & Reviews 15(6):102268.

Prado, B. N., & Vaccarezza, G. F. 2017. “Alterações Bucais Em Pacientes Diabéticos.” Revista de Odontologia Da Universidade Cidade de São Paulo 25(2):147.

Rizzo, M. R., Di Meo, I., Polito, R., Auriemma, M. C., Gambardella, A., di Mauro, G., Capuano, A., & Paolisso, G. 2022. “Cognitive Impairment and Type 2 Diabetes Mellitus: Focus of SGLT2 Inhibitors Treatment.” Pharmacological Research 176:106062.

Rodrigues, C. F., Rodrigues, M. E., & Henriques, M. 2019. “Candida Sp. Infections in Patients with Diabetes Mellitus.” Journal of Clinical Medicine 8(1).

Rohani, B. 2019. “Oral Manifestations in Patients with Diabetes Mellitus.” World Journal of Diabetes 10(9):485–89.

Saghiri, M. A., Tang, C. K., & Nath, D. 2021. “Downstream Effects from Diabetes Mellitus Affected on Various Tooth Tissues: A Mini Review: Effects of Diabetes on Tooth Structure.” Dentistry Review 1(1):100002.

Segura-Egea, J. J., L. Castellanos-Cosano, G., Machuca, J., López-López, J., Martín-González, E., Velasco-Ortega, B., Sánchez-Domínguez, & F. J. López-Frías. 2012. “Diabetes Mellitus, Periapical Inflammation and Endodontic Treatment Outcome.” Medicina Oral, Patologia Oral y Cirugia Bucal 17(2):e356–61.

Taboza, Z. A., Costa, K. L., Silveira, V. R., Furlaneto, F. A., Montenegro, R. Jr., Russell, S., Dasanayake, A., & Rodrigo, O. R. 2018. “Periodontitis, Edentulism and Glycemic Control in Patients with Type 2 Diabetes: A Cross-Sectional Study.” BMJ Open Diabetes Research & Care 6(1):e000453.

Viellas, E. F. V., Domingues, R. M. S. Madeira., Dias, A. B. D., & Costa, J. V. 2013. “Manifestações Bucais Em Pacientes Portadores de Diabetes Mellitus: Uma Revisão Sistemática Oral Manifestations in Patients with Diabetes Mellitus: A Systematic Review.” Rev Odontol UNESP 42(3):211–20.

Published

06/09/2022

How to Cite

FERNANDES , J. D. L.; BOMFIM, R. M.; FRANÇA , C. R.; CARNEIRO , G. K. M. .; SILVA, A. C. R. da .; NASCIMENTO NETO , E. V. do .; SANTOS, M. G. dos .; SILVA, G. C. da .; CABRAL , E. C. C. .; SANTOS, A. L. L. . Oral manifestations in patients with Diabetes mellitus. Research, Society and Development, [S. l.], v. 11, n. 12, p. e44111234330, 2022. DOI: 10.33448/rsd-v11i12.34330. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/34330. Acesso em: 22 nov. 2024.

Issue

Section

Health Sciences