Thyroid disorders and Covid-19: a literature review




Thyroid gland diseases; Covid-19; Thyroid gland; Subacute thyroiditis; Angiotensin 2 converting enzyme.


COVID-19 is a highly contagious disease caused by SARS-CoV-2, a single-stranded, enveloped RNA virus belonging to the beta-coronavirus family. SARS-CoV-2 is phylogenetically related to SARS-CoV-1, the virus that causes severe acute respiratory syndrome (SARS). Like SARS-CoV-1, SARS-CoV-2 infects human tissues by entering cells via the angiotensin-converting enzyme 2 (ACE2) receptor. It was alarming that, during the SARS-CoV-1 outbreak, many infected patients had thyroid gland disorders, even causing severe cellular damage. As SARS-CoV-2 is similar to SARS-CoV-1, researchers began to assess the possibility of developing thyroid diseases, especially subacute thyroiditis, in infected patients. Objective: To establish a possible relationship between the development of thyroid disorders and the infectious process caused by SARS-CoV-2 infection. Method: Literature review, supported by results obtained in studies related to the topic. Results: Studies carried out in the different stages of SARS-COV-2 infection suggest the existence of an association between SARS-CoV-2 infection and changes in thyroid function. Conclusion: Although most patients are euthyroid or have subacute thyroiditis, other thyroid diseases can manifest during SARS-CoV-2 infection, indicating the importance of assessing thyroid function in hospitalized, symptomatic and asymptomatic patients.


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How to Cite

PINHEIRO, F. C. M. .; PINHEIRO, H. C. M. .; PINHEIRO, J. D. M. .; ABREU, J. D. M. F. de .; SOBRAL, C. S. P. . Thyroid disorders and Covid-19: a literature review. Research, Society and Development, [S. l.], v. 11, n. 14, p. e390111435546, 2022. DOI: 10.33448/rsd-v11i14.35546. Disponível em: Acesso em: 2 dec. 2023.



Health Sciences