Overview of HSV infection: an integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i15.36141

Keywords:

Genital herpes; Lip herpes; Herpes simplex; Herpes simplex virus vaccines.

Abstract

The present research aims to carry out an integrative review of the literature regarding the infection by the herpes viruses (HSV-1 and HSV-2), aiming at the elucidation of clinical aspects and complications associated with the infection, as well as the presentation of epidemiological data, forms of transmission, characteristics of the pathogen, and the development of vaccines, discussed superficially in this review. In addition, data on the disease in Brazil are presented between January 2019 and April 2020 and between January 2021 and April 2022. The international databases PubMed, SciELO and LILACS were used during the searches, as well as information from the World Health Organization were selected. Thus, 30 scientific articles were selected to compose the bibliographic base of the current review, according to the pre-established inclusion and exclusion criteria.

References

Xu, X., Zhang, Y., & Li, Q. (2019). Characteristics of herpes simplex virus infection and pathogenesis suggest a strategy for vaccine development. Reviews in medical virology, 29(4), e2054.

Johnston, C., & Corey, L. (2016). Current concepts for genital herpes simplex virus infection: diagnostics and pathogenesis of genital tract shedding. Clinical microbiology reviews, 29(1), 149-161.

Sadowski, L. A., Upadhyay, R., Greeley, Z. W., & Margulies, B. J. (2021). Current drugs to treat infections with herpes simplex viruses-1 and-2. Viruses, 13(7), 1228.

Sivarajah, V., Venus, K., Yudin, M. H., Murphy, K. E., Morrison, S. A., & Tan, D. H. (2017). Does maternal HSV-2 coinfection increase mother-to-child transmission of HIV? A systematic review. Sexually Transmitted Infections, 93(8), 535-542.

AlMukdad, S., Harfouche, M., Wettstein, A., & Abu-Raddad, L. J. (2021). Epidemiology of herpes simplex virus type 2 in Asia: A systematic review, meta-analysis, and meta-regression. The Lancet Regional Health-Western Pacific, 12, 100176.

Harfouche, M., Abu-Hijleh, F. M., James, C., Looker, K. J., & Abu-Raddad, L. J. (2021). Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions. EClinicalMedicine, 35, 100876.

Patterson, J., Hitti, J., Selke, S., Huang, M. L., Watts, D. H., Brown, Z., ... & Wald, A. (2011). Genital HSV detection among HIV-1-infected pregnant women in labor. Infectious diseases in obstetrics and gynecology, 2011.

James, C., Harfouche, M., Welton, N. J., Turner, K. M., Abu-Raddad, L. J., Gottlieb, S. L., & Looker, K. J. (2020). Herpes simplex virus: global infection prevalence and incidence estimates, 2016. Bulletin of the World Health Organization, 98(5), 315.

Tan, D. H. S., Murphy, K., Shah, P., & Walmsley, S. L. (2013). Herpes simplex virus type 2 and HIV disease progression: a systematic review of observational studies. BMC infectious diseases, 13(1), 1-10.

Aebi-Popp, K., Bailey, H., Malyuta, R., Volokha, A., & Thorne, C. (2016). High prevalence of herpes simplex virus (HSV)-type 2 co-infection among HIV-positive women in Ukraine, but no increased HIV mother-to-child transmission risk. BMC pregnancy and childbirth, 16(1), 1-9.

World Health Organization (WHO). "Herpes simplex virus". 10 March 2022. https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus

Chemaitelly, H., Weiss, H. A., & Abu-Raddad, L. J. (2020). HSV-2 as a biomarker of HIV epidemic potential in female sex workers: meta-analysis, global epidemiology and implications. Scientific reports, 10(1), 1-11.

Des Jarlais, D. C., Arasteh, K., McKnight, C., Perlman, D. C., Feelemyer, J., Hagan, H., & Cooper, H. L. (2014). HSV-2 co-infection as a driver of HIV transmission among heterosexual non-injecting drug users in New York City. PloS one, 9(1), e87993.

Johnston, C., Koelle, D. M., & Wald, A. (2011). HSV-2: in pursuit of a vaccine. The Journal of clinical investigation, 121(12), 4600-4609.

Mohraz, M., Aghakhani, A., Moayedi-Nia, S., Banifazl, M., Janbakhsh, A., Mamishi, S., ... & Ramezani, A. (2018). No role of herpes simplex virus type 2 (HSV-2) infection on HIV progression in naïve HIV patients. Iranian biomedical journal, 22(2), 123.

Pinninti, S. G., & Kimberlin, D. W. (2014). Preventing herpes simplex virus in the newborn. Clinics in perinatology, 41(4), 945-955.

Stanfield, B. A., Kousoulas, K. G., Fernandez, A., & Gershburg, E. (2021). Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses. Viruses, 13(8), 1637.

Varo, R., Chris Buck, W., Kazembe, P. N., Phiri, S., Andrianarimanana, D., & Weigel, R. (2016). Seroprevalence of CMV, HSV-2 and HBV among HIV-infected Malawian children: a cross-sectional survey. Journal of tropical pediatrics, 62(3), 220-226.

Domercant, J. W., Jean Louis, F., Hulland, E., Griswold, M., Andre-Alboth, J., Ye, T., & Marston, B. J. (2017). Seroprevalence of Herpes Simplex Virus type-2 (HSV-2) among pregnant women who participated in a national HIV surveillance activity in Haiti. BMC infectious diseases, 17(1), 1-7.

Munawwar, A., Gupta, S., Sharma, S. K., & Singh, S. (2018). Seroprevalence of HSV-1 and 2 in HIV-infected males with and without GUD: Study from a tertiary care setting of India. Journal of laboratory physicians, 10(03), 326-331.

Khadr, L., Harfouche, M., Omori, R., Schwarzer, G., Chemaitelly, H., & Abu-Raddad, L. J. (2019). The epidemiology of herpes simplex virus type 1 in Asia: systematic review, meta-analyses, and meta-regressions. Clinical Infectious Diseases, 68(5), 757-772.

Barnabas, R. V., Webb, E. L., Weiss, H. A., & Wasserheit, J. N. (2011). The role of co-infections in HIV epidemic trajectory and positive prevention: a systematic review and meta-analysis. AIDS (London, England), 25(13), 1559.

Kim, H. C., & Lee, H. K. (2020). Vaccines against genital herpes: where are we?. Vaccines, 8(3), 420.

Egan, K., Hook, L. M., LaTourette, P., Desmond, A., Awasthi, S., & Friedman, H. M. (2020). Vaccines to prevent genital herpes. Translational Research, 220, 138-152.

Looker, K. J., Elmes, J. A., Gottlieb, S. L., Schiffer, J. T., Vickerman, P., Turner, K. M., & Boily, M. C. (2017). Effect of HSV-2 infection on subsequent HIV acquisition: an updated systematic review and meta-analysis. The Lancet infectious diseases, 17(12), 1303-1316.

Pereira, V. S., Moizeis, R. N., Fernandes, T. A., Araújo, J. M., Meissner, R. V., & Fernandes, J. V. (2012). Herpes simplex virus type 1 is the main cause of genital herpes in women of Natal, Brazil. European Journal of Obstetrics & Gynecology and Reproductive Biology, 161(2), 190-193.

Mujugira, A., Magaret, A. S., Baeten, J. M., Celum, C., & Lingappa, J. (2011). Risk factors for HSV-2 infection among sexual partners of HSV-2/HIV-1 Co-infected persons. BMC Research Notes, 4(1), 1-6.

Rocha, D. A. P., Mariño, J. M., & Santos, C. M. B. D. (2012). Detecção de Citomegalovírus Humano e Herpesvírus Simples tipo 2 em amostras cervicais. Revista Brasileira de Ginecologia e Obstetrícia, 34, 499-504.

Clemens, S. A. C., & Farhat, C. K. (2010). Soroprevalência de anticorpos contra vírus herpes simples 1-2 no Brasil. Revista de Saúde Pública, 44(4), 726-734.

Nakku-Joloba, E., Kambugu, F., Wasubire, J., Kimeze, J., Salata, R., Albert, J. M., ... & Whalen, C. (2014). Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda. African health sciences, 14(4), 782-789.

Downloads

Published

10/11/2022

How to Cite

SOUZA, I. S. M. de .; PEREIRA, L. M. de A. .; GUEDES, T. V. S. do M. .; ARAÚJO, J. M. de .; COSTA, A. L. dos S. .; PEREIRA, R. B. .; ARAÚJO, H. D. A. de .; NOGUEIRA FILHO, R. M.; NASCIMENTO JÚNIOR, J. A. A. do; MACIEL, N. G. P. .; SILVA JÚNIOR, J. G. da . Overview of HSV infection: an integrative literature review. Research, Society and Development, [S. l.], v. 11, n. 15, p. e61111536141, 2022. DOI: 10.33448/rsd-v11i15.36141. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36141. Acesso em: 25 dec. 2024.

Issue

Vol. 11 No. 15

Section

Review Article

License

Copyright (c) 2022 Isaias Sena Moraes de Souza; Laura Maria de Araújo Pereira; Talyta Valeria Siqueira do Monte Guedes; Janemary Malheiro de Araújo; Ana Lucila dos Santos Costa; Rafaell Batista Pereira; Hallysson Douglas Andrade de Araújo; Ricardo Marques Nogueira Filho; José Adelson Alves do Nascimento Júnior; Nadine Gabryella Pontes Maciel; José Guedes da Silva Júnior

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.