Clinical and pathological aspects of anaplastic sarcoma with giant cells in a feline with inguinal lymph node metastasis: case report
Keywords:Feline Medicine; Cytology; Histopathology; Diagnosis; Anaplastic sarcoma; Giant cells.
Anaplastic sarcoma is considered a histological variant of the feline application sarcoma entity and may be related to drug injections. Therefore, this objective work relates to a case of anaplastic giant cell sarcoma in the right region in a feline with the presence of metastasis in the right inguinal lymph node, emphasizing its clinical and pathological findings. The patient came to the service complaining of an increase in volume in the right flank region, with evolution of 40 days and progressive growth. Aspiration cytology. result suggestive of giant cells Laboratory and imaging tests were also performed to rule out possible metastases. In addition to the lymphadenectomy performed, there is a need for local lymphadenectomy. for cells and lymph node examinations were confirmed for histopathological examination giants with inguinal lymph nodes. After the surgical procedure presented local recurrence, for personal reasons, the tutor chose not to perform new integrated resection procedures and not perform adjuvant therapies for tumor control, being performed therapies to support the patient's quality of life. In this way, it is concluded that all clinical procedures must be performed in all clinical imaging exams, cytology even more their clinical conduct before all surgical procedures.
Bertram, C. A., et al. (2020). Giant Cell Sarcomas in Domestic Rabbits (Oryctolagus cuniculus). Veterinary Pathology. 57(4), 490-6.
Buracco, P. (2015). Canine and feline soft tissue sarcomas. Apresentado e publicado no CD de Proceedings do XXIII Congresso Nacional APMVEAC: Oncologia, neurologia e patologia clínica, Lisboa, Portugal.
Cecco, B., et al. (2020). Feline giant-cell pleomorphic sarcoma: cytologic, histologic and immunohistochemical characterization. Journal Of Feline Medicine And Surgery. 52(4), 1-7.
Chalira, M. C. C., & Reche, J. R. A. (2003). Fibrossarcoma. In: Souza, H.J.M. Coletâneas em Medicina e Cirurgia Felina. (6a. ed.) (v.3., pp. 215-224). Elsevier.
Davidson, E. B., Gregory, C. R., & Kass, P. H. (1997). Surgical excision of soft tissue fibrosarcomas in cats. Veterinary Surgery. 26(4), 265-278.
Ferrari, R., Di Giancamillo, M., Stefanello, D., et al. (2015). Clinical and computed tomography tumour dimension assessments for planning wide excision of injection site sarcomas in cats: how strong is the agreement? Veterinary and Comparative Oncology. 59(4), doi: 10.1111/vco.12173.
Ferreira, M. G. P. A. (2016). Sarcoma de Aplicação em Felinos: Aspectos Clínicos, Diagnóstico e Terapia. Revista Investigação. 15(7), 29-36.
Hartmann, K., Day, M. J., Thiry, E., et al. (2015). Feline injection-site sarcoma ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery. 17(2), 606–613.
Kass, P. H., et al. (1993). Epidemiologic evidence for a causal relation between vaccination and fibrosarcoma tumorigenesis in cats. Journal of the American Veterinary Medical Association. 203(3), 396-405.
Krygier, J., & Lewis, V.O. (2009). Fibrosarcoma of bone: a review of a rare primary malignancy of bone. Electronic Sarcoma Update Newsletter. 6(2), 44-56.
Kliczkowska, K., et al. (2015). Epidemiological and morphological analysis of feline injection site sarcomas. Polish journal of veterinary science. 18(2), 12-22.
Ladlow, J. (2013). Injection site-associated sarcoma in the cat: treatment recommendations and results to date. Journal of Feline Medicine and Surgery.15(5), 409-418.
Lima, C., Leite, C., & Cavalcante, G. (2007). Sarcomas Pós vacinais em Felinos. Revista Nosso Clinico. 60(1), 46-53.
Liptak, J. M., & Forrest, L. J., (2012). Soft Tissue Sarcomas in: Withrow, S.J., Vail, D.M., Withrow., & MacEwen's. (Ed.) Small Animal Clinical Oncology. (pp. 425-454). Saint Louis: Elsevier Saunders.
Nobrega, C., Mesquita, J. R., Cruz, R., Coelho, C., Esteves, F., Mega, A. C., Santos, C.,Vala, H. (2016). Feline injection site sarconas. American journal of veterinary research.7(2), 9-17.
Porcellato, I., et al. (2017). Feline injection-site sarcoma: matrix remodeling and prognosis. Veterinary pathology. 54(2), 204-211.
Richards, J. R., et al. (2005). The current understanding and management of vaccine-associated sarcomas in cats. Journal of the American Veterinary Medical Association. 226(11), 1821-1842.
Ryan, S., et al. (2012). Skin and subcutaneous tumors. In: Kudnig, S.T & Séguin, B. (Ed.), Veterinary surgical oncology. (pp. 55-85). Lowa: Wiley-Blackwell.
Rousset, N., et al. (2013). Clinical and low‐field MRI characteristics of injection site sarcoma in 19 cats. Veterinary Radiology & Ultrasound. 54(6), 623-629.
Saba, C. F. (2017). Vaccine-associated feline sarcoma: current perspectives. Veterinary Medicine: Research and Reports. 8(1), 13.
Travetti, O., et al. (2013). Computed tomography characteristics of fibrosarcoma— a histological subtype of feline injection-site sarcoma. Journal of feline medicine and surgery. 15(6), 488-493.
Williams, L. E., et al. (2001). Establishment of two vaccine-associated feline sarcoma cell lines and determination of in vitro chemosensitivity to doxorubicin and mitoxantrone. American journal of veterinary research. 62(9), 1354-1357.
Zimmermann, K., Hossann, M., Hirschberger, J., Troedson, K., Peller, M., Schneider, M, & Wergin, M. (2017). A pilot trial of doxorubicin containing phosphatidyldiglycerol based thermosensitive liposomes in spontaneous feline soft tissue sarcoma. International Journal of Hyperthermia. 33(2), 178-190.
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