Analysis of epidemiological and hospital characteristics of spina bifida related to cases registered in Brazil in the last 5 years

Authors

DOI:

https://doi.org/10.33448/rsd-v11i16.37891

Keywords:

Spinal dysraphism; Public health; Epidemiology.

Abstract

Spina bifida is defined as a defect in the posterior bone closure of the spine, and the causes are related to the interaction of genetic and environmental factors. Children with spina bifida carry complications that make the pathology a serious public health problem, whose repercussion ranges from their families to the community with which they live. Therefore, the present study proposes to analyze hospitalizations for spina bifida, in the pediatric population, in Brazil and its regions, in the last 5 years. This is a descriptive, retrospective and analytical study about hospitalizations resulting from spina bifida, prepared through secondary data obtained from the Hospital Information System of the Unified Health System, in children under 1 year old to 19 years old, from 2017 to 2021, in Brazil and its macro-regions. In the analyzed period, there were 4,823 hospitalizations for spina bifida, in children aged between 1 year and 19 years, in Brazil. Regarding geographic regions, the largest number of hospitalizations is concentrated in the Northeast region. Regarding the age group, patients younger than 1 year were the most affected. Regarding gender, females predominated. As for the reported ethnicity of the hospitalized patients, the highest number of cases prevailed among those hospitalized of white ethnicity. With this, it is possible to point out patients hospitalized for spina bifida, in children aged between 1 year and 19 years, as a public health problem that deserves the attention of the government and Brazilian society in general.

References

Aguiar, M. J. B., et al. (2003). Defeitos de fechamento do tubo neural e fatores associados em recém-nascidos vivos e natimortos. Jornal de Pediatria, 79, 129–134. https://doi.org/10.1590/S0021-75572003000200007

Bevilacqua, N. S., & Pedreira, D. A. L. (2015). Fetoscopy for meningomyelocele repair: past, present and future. Einstein (São Paulo), 13(2), 283–289. https://doi.org/10.1590/s1679-45082015rw3032

Bizzi, J. W. Junqueira, & Machado, A. (2018). Mielomeningocele. JBNC – Jornal Brasileiro de Neurocirurgia, 23(2), 138–151. https://doi.org/10.22290/jbnc.v23i2.1161

Brasil. (2002) Agência Nacional de Vigilância Sanitária. Resolução RDC n. 344, de 13 de dezembro de 2002. Aprova o Regulamento Técnico para a Fortificação das Farinhas de Trigo e das Farinhas de Milho com Ferro e Ácido Fólico. Diário Oficial da União, Brasília, DF, 18 dez. 2002. https://bvsms.saude.gov.br/bvs/saudelegis/anvisa/2002/rdc0344_13_12_2002.html

Brasil. (2020). Ministério da Saúde. Portaria MS/GM n. 356, de 11 de março de 2020. Dispõe sobre a regulamentação e operacionalização do disposto na Lei nº 13.979, de 6 de fevereiro de 2020, que estabelece as medidas para enfrentamento da emergência de saúde pública de importância internacional decorrente do coronavírus (COVID-19) [Internet]. Diário Oficial da União, Brasília (DF); Seção 1:185. http://www.in.gov.br/web/dou/-/portaria-n-356-de-11-de-marco-de-2020-247538346

Bunduki, V., et al. (2016). Comparison of Two- and Three-dimensional Ultrasonography in the Evaluation of Lesion Level in Fetuses with Spina Bifida. Revista Brasileira de Ginecologia E Obstetrícia / RBGO Gynecology and Obstetrics, 38(03), 120–126. https://doi.org/10.1055/s-0036-1580711

Buoro, R. S., & Nogueira, M. P. (2020). Qualidade de vida e desafios de familiares de crianças com mielomeningocele. Acta Ortopédica Brasileira, 28(6), 291–295. https://doi.org/10.1590/1413-785220202806237160

Coniglio, S. J., Anderson, S. M., & Ferguson, J. E. (1997). Developmental outcomes of children with myelomeningocele: Prenatal predictors. American Journal of Obstetrics and Gynecology, 177(2), 319–324. https://doi.org/10.1016/s0002-9378(97)70193-5

Conselho nacional de saúde - Página Inicial. (n.d.). Conselho.saude.gov.br. Https://conselho.saude.gov.br/Resolucoes/2016/Reso510.pdf

Cortés M., F. (2003). Prevención primaria de los defectos de cierre del tubo neural. Revista Chilena de Pediatría, 74(2). https://doi.org/10.4067/s0370-41062003000200011

Cunha, C. et al. (2005). Fatores genéticos e ambientais associados a espinha bífida. Revista Brasileira de Ginecologia E Obstetrícia, 27(5). https://doi.org/10.1590/s0100-72032005000500007

Gaíva, M. A. M., corrêa, E. R., & santo, E. A. R. DO E. (2011). Perfil clínico-epidemiológico de crianças e adolescentes que vivem e convivem com espinha bífida. Journal of Human Growth and Development, 21(1), 99–110. https://doi.org/10.7322/jhgd.19999

Horovitz, D. D. G., Ilerena JR., J. C., & mattos, R. A. de. (2005). Atenção aos defeitos congênitos no Brasil: panorama atual. Cadernos de Saúde Pública, 21(4), 1055–1064. https://doi.org/10.1590/s0102-311x2005000400008

Kiely, M. (2019). Reproductive and Perinatal Epidemiology (M. Kiely, Ed.). CRC Press. https://doi.org/10.1201/9780429278341

Orioli, I. M. et al. (2011). Effects of folic acid fortification on spina bifida prevalence in Brazil. Birth Defects Research Part A: Clinical and Molecular Teratology, 91(9), 831–835. https://doi.org/10.1002/bdra.20830

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. UFSM.

Scott Adzick, N. (2013). Fetal surgery for spina bifida: Past, present, future. Seminars in Pediatric Surgery, 22(1), 10–17. https://doi.org/10.1053/j.sempedsurg.2012.10.003

The global burden of disease. (2004). https://apps.who.int/iris/bitstream/handle/10665/43942/9789241563710_eng.pdf

Torkelson, R. D. (1987). Book Review: Textbook of Child Neurology, ed 3, by John H. Menkes. Published in 1985 by Lea & Febiger, Philadelphia, 827 pages, $58.50. Journal of Child Neurology, 2(3), 235–236. https://doi.org/10.1177/088307388700200315

Vieira, A. R., & Castillo taucher, S. (2005). Edad materna y defectos del tubo neural: evidencia para un efecto mayor en espina bífida que anencefalia. Revista Médica de Chile, 133(1). https://doi.org/10.4067/s0034-98872005000100008

World health organization (2003). World Atlas of Birth Defects. (2a ed.). Geneva.

Published

30/11/2022

How to Cite

ROSA, M. M. .; ABBOUD, L. F. J. .; FRANÇA, T. F. .; ALCANTARA, V. H. F. .; ANDRADE, J. S. de .; MUNIZ, J. P. P. .; SILVA, B. S. da .; MENDES, M. C. .; PERRONI, C.; SILVA, E. L. D. da . Analysis of epidemiological and hospital characteristics of spina bifida related to cases registered in Brazil in the last 5 years. Research, Society and Development, [S. l.], v. 11, n. 16, p. e87111637891, 2022. DOI: 10.33448/rsd-v11i16.37891. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/37891. Acesso em: 25 nov. 2024.

Issue

Section

Health Sciences