Use of plant-derived antidepressants and anxiolytics by medical students at a public university in the northeastern region of Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v11i16.38503

Keywords:

Phytotherapeutic drugs; Depression; Anxiety; Student.

Abstract

Studies report a close relationship between the increase of anxiety and depression disorders in the young population and academic routine, especially when considering the medical course. At the same time, due to the easy access and the popular belief of harmlessness, nervous system acting herbal medicines are being much sought after by this group. Thus, this research aimed to trace the consumption profile of central nervous system acting natural products in medical students at a public university in northeastern Brazil. To this end, information was collected through an online form containing specific direct questions to medical students from a public university in northeastern, considering the inclusion and exclusion factors. It was registered on the Brazil Platform of the Ministry of Health. – CAAE No. 50027121.0.0000.5011. The study had 125 participants, where 59 participants claimed to use or have used nervous system acting herbal medicines, with Passiflora incarnata and Valeriana officinalis being the most used species. Inadequate practices were found, such as self-medication and prescription change. College related issues proved to be important psychosocial stressors and incentives for the use of natural psychotropic drugs. Finally, the research presented similarities with the literature, evidencing a wide use, without proper professional advice, of herbal medicines among medical students.

References

Abbas, G., Naqvi, S., Erum, S., Ahmed, S., Rahman, A. & Dar, A. (2013). Potential antidepressant activity of Areca catechu nut via elevation of serotonin and noradrenaline in the hippocampus of rats. Phytotherapy Research, 27(1), 39–45.

Aaker, D. A., Kumar, V., & Day, G. S (2007). Pesquisa de marketing. Atlas, 2.

Andrews, B. & Wilding, J. M. (2004). The relation of depression and anxiety to life-stress and achievement in students. British Journal of Psychology, 95(4), 509-521.

Awad, A. & Al-Shaye, D. (2014). Public awareness, patterns of use and attitudes toward natural health products in Kuwait: a cross-sectional survey. BMC Complementary and Alternative Medicine, 14(105), n.p.

Çelik, N., Ceylan, B., Ünsal, A. & Çağan Ö. (2019). Depression in health college students: relationship factors and sleep quality. Psychology, Health & Medicine, 24(5), 625-630.

Consolini, A. E. & Ragone, M. I. (2010). Patterns of Self-Medication with Medicinal Plants and Related Adverse Events - A South American Survey. Current Drug Safety, 5, 333-341.

Eisenberg, D., Gollust, S.E., Golberstein, E. & Hefner, J.L. (2007). Prevalence and Correlates of Depression, Anxiety, and Suicidality Among University Students. American Journal of Orthopsychiatry, 77(4), 534-542.

Fajemiroye, J.O., da Silva, D.M., de Oliveira, D.R. & Costa E.A. (2016). Treatment of anxiety and depression: medicinal plants in retrospect. Fundamental & Clinical Pharmacology, 30(3), 198–215.

Feldman, R. H & Laura, R. (2004). Alternative Medicine Practices Among Australian University Students. Complementary Health Practice Review, 9(3), 173-179.

Firth, J. (1986). Levels and sources of stress in medical students. British Medical Journal, 292, 1177-1180.

Fond, G., Bourbon, A., Boucekine, M., Messiaen, M., Barrow, V., Auquier, P. …& Boyer, L. First-year French medical students consume antidepressants and anxiolytics while second-years consume non-medical drugs. Journal of Affective Disorders, 265(1), 71–76.

Gaultney, J. F. (2010). The prevalence of sleep disorders in college students: Impact on academic performance. Journal of American College Health, 59(2), 91-97.

Gonçalves, D. I. F. (2008). Pesquisas de marketing pela internet: As percepções sob a ótica dos entrevistados. Revista de Administração Mackenzie, 9, 7.

Jang, S., Kim, K.H., Sun, S.H., Go, H.Y., Lee, E.K., Jang, B.H. … & Ko, S.G. (2017). Characteristics of Herbal Medicine Users and Adverse Events Experienced in South Korea: A Survey Study. Evidence-Based Complementary and Alternative Medicine.

Khairy, W.A., Nasser, H.A., Sarhan, M.D., El Shamy, A.A. & Galal, Y.S. (2021). Prevalence and Predictors of Self-Medication with Antifungal Drugs and Herbal Products Among University Students: A Cross-Sectional Study from Egypt. Risk Management and Healthcare Policy, 14, 2191-2200.

Kim, J., Kim, S.Y., Lee, S. & Jang, C.(2007). Antidepressant like effects of Albizzia julibrissin in mice: involvement of the 5-HT1A receptor system. Pharmacology Biochemistry and Behavior, 87, 41–47.

Lancet. (2022). Ensuring care for people with depression. Lancet, 399(10328), Editorial.

Lun, K. W., Chan, C.K., Ip, P.K., Ma, S.Y., Tsai, W.W., Wong, C.S. …& Yan, D. (2018). Depression and anxiety among university students in Hong Kong. Hong Kong Medical Journal, 24(1), 466–472.

Lund, H. G., Reider, B.D., Whiting, A.B., & Prichard, J.R. (2010). Sleep patterns and predictors of disturbed sleep in a large population of college students. Journal Adolescent Health, 46(2), 124-132.

Machado, D. G., Kaster, M. P., Binfaré, R. W., Dias, M., Santos, A.R.S, Pizzolatti, M. G. ...& Rodrigues, A.L.S. (2017). Antidepressant-like effect of the extract from leaves of Schinus molle L. in mice: evidence for the involvement of the monoaminergic system. Progress in neuro-psychopharmacology & biological psychiatry, 31, 421–428.

Nardoff, M.R., Nazem, S., & Fiske, A. (2011) Insomnia symptoms, nightmares, and suicidal ideation in a college student sample. SLEEP. 34(1), 93–98.

Organização Panamericana Da Saúde - OPAS. Depressão. https://www.paho.org/pt/topicos/depressao.

Ribeiro, A.G, da Cruz, L.P., Marchi, K. C., Tirapelli, C.R., & Miasso, A. I. (2014). Antidepressivos: uso, adesão e conhecimento entre estudantes de medicina. Ciência e Saúde Coletiva, 19(6), 1825-1833

Sarris, J., Panossian, A., Schweitzer, I., Stough, C., & Scholey, A. (2011). Herbal medicine for depression, anxiety and insomnia: A review of psychopharmacology and clinical evidence. European Neuropsychopharmacology, 21(1), 841–860.

Sawalha, A.F., Sweileh, W.M., Zyoud, S.H., & Jabi, S.W. (2008) Self-therapy practices among university students in Palestine: Focus on herbal remedies. Complementary Therapies in Medicine, 16(1), 343-349.

Shao, R., He, P., Ling, B., Tan, L., Xu, L., Hou, Y. …. & Yang, Y. (2020). Prevalence of depression and anxiety and correlations between depression, anxiety, family functioning, social support and coping styles among Chinese medical students. BMC Psychology. 8(38).

Souza, F. G. M., & Menezes, M. G. C. (2005) Estresse nos estudantes de medicina da Universidade Federal do Ceará. Revista Brasileira Educação Médica, 29(2), 91-96.

Taylor, D.J., Gardner, C.E., Bramoweth, A.D., Williams, J.M., Roane, B.M., Grieser, E.A. ... & Tatum, J.I. (2011) Insomnia and mental health in college students. Behavioral Sleep Medicine, 9(2), 107-116.

Tempski, P., Bellodi, P.L., Paro, H.B., Enns, S.C., Martins, M.A., & Schraiber, L.B. (2012). What do medical students think about their quality of life? A qualitative study. BMC Medical Education, 12(106).

Touiti, N., Houssaini, T.S., Iken, I., Benslimane, A. & Achour, S. (2020). Prevalence of herbal medicine use among patients with kidney disease: A cross-sectional study from Morocco. Néphrologie & Thérapeutique, 16(1), 43-49.

Welz, A. N, Emberger-Klein, A & Menrad, K. (2019). What motivates new, established and longterm users of herbal medicine: is there more than push and pull?. BMC Complementary and Alternative Medicine, 19, 170.

Wolf, T.M., Randall, H.M., Von Almen, K., & Tynes, L.L. (1991). Perceived mistreatment and attitude change by graduating medical students: a retrospective study. Medical Education, 25, 182-190.

World Health Organization (WHO). (2017). Depression and other common mental disorders: global health estimates. Geneva: WHO. http://apps.who.int/iris/bitstream/10665/254610/1/WHO-MSD-MER-2017.2-eng.pdf.

Zhai, L., Zhang, Y., & Zhang, D. (2015). Sedentary behaviour and the risk of depression: a meta-analysis. British Journal Sports Medicine. 49(11), 705-709.

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Published

13/12/2022

How to Cite

OLIVEIRA JÚNIOR, L. N. de .; CARNAÚBA, A. de A. .; BARBOSA, A. S. L. .; RIBEIRO, M. C.; TEIXEIRA, M. do C.; SILVA, J. C. . Use of plant-derived antidepressants and anxiolytics by medical students at a public university in the northeastern region of Brazil . Research, Society and Development, [S. l.], v. 11, n. 16, p. e421111638503, 2022. DOI: 10.33448/rsd-v11i16.38503. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/38503. Acesso em: 22 nov. 2024.

Issue

Vol. 11 No. 16

Section

Health Sciences

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Copyright (c) 2022 Luis Nunes de Oliveira Júnior; Annaliz de Araújo Carnaúba; Ana Soraya Lima Barbosa; Mara Cristina Ribeiro; Maria do Carmo Teixeira; Juliane Cabral Silva

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