Comparison of mortality between early and late tracheostomy in patients hospitalized by COVID-19 in an intensive care unit
DOI:
https://doi.org/10.33448/rsd-v12i1.39679Keywords:
Intensive Care Unit; Tracheostomy; COVID-19; SARS-CoV-2.Abstract
Introduction: COVID-19 is an acute respiratory infection caused by the SARS-CoV-2 coronavirus, potentially serious, highly transmissible and globally distributed. Objective: to analyze the impact of early and late tracheostomy (TQT) in patients with COVID-19 on the type of ventilatory weaning and mortality. Methodology: This study will be a retrospective observational cohort, evaluating patients diagnosed with COVID-19 admitted to an Intensive Care Unit (ICU) of a tertiary center in the city of Aracaju, SE, from November 2020 to July 2020. 2021. The collection will be guided by a structured collection form with variables of interest. The primary outcome will be the in-hospital mortality within 60 days, from the date of the TQT performance, compared between patients who were tracheostomized early and those who were late. Results: A total of 197 patients were admitted to the ICU, but only 72 were eligible for inclusion in the study. The “early TQT” group had less time on ventilator, as well as ICU stay, but no difference was found between the time from performing the procedure until the occurrence of the outcome. Conclusion: After a thorough analysis of the data, it is suggested that the process of hospitalization in the ICU and COVID-19 increased the need for the tracheostomy procedure, but the study was not significant when we compared the mortality outcome in the group that performed it early or late the procedure.
References
Adly, A., Youssef, T. A., El-Begermy, M. M., & Younis, H. M. (2017) Timing of tracheostomy in patients with prolonged endotracheal intubation: a systematic review. Eur Arch OtoRhino-Laryngology. 275, (3): 679–90.
Agência IBGE de notícias. <https://agenciadenoticias.ibge.gov.br/agencia-noticias/2012-agencia-de noticias/noticias/25882-extrema-pobreza-atinge-13-5-milhoes-de-pessoas-e-chega-ao-maior-nivel-em7-anos
Aranha, S. C. et al. (2017) Estudo comparativo entre traqueostomia precoce e tardia em pacientes sob ventilação mecânica. Revista Brasileira de Terapia Intensiva. 19(4), 444–449.
Assis, L. G. R., Neto, C. S. N., Santos, G. S., Santos, A. W., Silva, C. H. S., Barros, J. F., Mendes, T. S., & Góes, M. A. O. (2020) Avaliação da mortalidade de uma UTI de Sergipe segundo escore fisiológico agudo simplificado 3 (SAPS 3). Rev. Epidemiol. Controle Infecç. Santa Cruz do Sul. 10(1):59-65.
Baptistella, A. et al. (2018) Predictive Factors of Weaning From Mechanical Ventilation and Extubation Outcome: A Systematic Review. J Crit Care.
Brito, S. B. P., Braga, I. O., Cunha, O. C., Palácio, M. A. V., Takenami, I. (2020) Pandemia da COVID-19: o maior desafio do século XXI. Vigil. sanit. Debate. 8(2):54-63.
Chao, T. N., Harbison, S. P., Braslow, B. M., Hutchinson, C. T., Rajasekaran, K., Go, B. C., Paul, E. A., Lambe, L. D., Kearney, J. J., Chalian, A. A., Cereda M. F., Martin, N. D., Haas, A. R., Atkins, J. H., Rassekh, C. H. (2020) Outcomes After Tracheostomy in COVID-19 Patients. Ann Surg. 1,272(3):181-186.
Chiang, S. S., Aboutanos, M. B., Jawa, R. S., Kaul, S. K., Houng, A. P., Dicker, R. A., & Guo, W. A. (2020) Controversies in Tracheostomy for Patients With COVID-19: The When, Where, and How. Respir Care. 2020 Nov,65(11):1767-1772.
Diretrizes Brasileiras de Ventilação Mecânica, 2013. Organizadores: Carmem Silvia Valente Barbas, Alexandre Marini Isola, Augusto Manoel de Carvalho Farias, 2013.
Escosteguy, C. C et al. (2020) COVID-19: estudo seccional de casos suspeitos internados em um hospital federal do Rio de Janeiro e fatores associados ao óbito hospitalar. Epidemiologia e Serviços de Saúde [online]. 30(1).
Ferro A, Kotecha S, Auzinger G, Yeung E, & Fan K. (2021) Systematic review and meta-analysis of tracheostomy outcomes in COVID-19 patients. Br J Oral Maxillofac Surg. 59(9):1013-1023.
Filho M, Raposo J. B et al. (2012) Os efeitos da ventilação mecânica no estresse oxidativo. Revista Brasileira de Terapia Intensiva [online]. 24(1), 23-29.
Fu Y, Cheng Y, & Wu Y. (2020) Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools. Virol Sin. 35(3):266-271.
Galvão, M. H. R. e R., Angelo G. (2020) Fatores associados a maior risco de ocorrência de óbito por COVID-19: análise de sobrevivência com base em casos confirmados. Revista Brasileira de Epidemiologia [online]. 23
Guedes J. M, Conceição S. L, & Albergaria T. (2018) Efeitos deletérios da ventilação mecânica invasiva em prematuros: revisão sistemática. Revista Pesquisa em Fisioterapia. 8(1):119.
Li X, Geng M, Peng Y, Meng L, & Lu S. (2020) Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal. 10(2):102-108.
Mahmood K, Cheng G. Z, Van Nostrand K, Shojaee S, Wayne M. T, Abbott M, Nettlow D, Parish A, Green CL, Safi J, Brenner M. J, & De Cardenas J. (2021) Tracheostomy for COVID-19 Respiratory Failure: Multidisciplinary, Multicenter Data on Timing, Technique, and Outcomes. Ann Surg. 1,274(2):234-239.
McGrath B. A., Brenner M. J, Warrillow S. J, Pandian V, Arora A, Cameron T. S, Añon J. M, Hernández Martínez G, Truog R. D, Block S. D, Lui G. C. Y, McDonald C, Rassekh C. H, Atkins J, Qiang L, Vergez S, Dulguerov P, Zenk J, Antonelli M, Pelosi P, Walsh B. K, Ward E, Shang Y, Gasparini S, Donati A, Singer M, Openshaw P. .J .M, Tolley N, Markel H, & Feller-Kopman D J. (2020) Tracheostomy in the COVID-19 era: global and multidisciplinary guidance. Lancet Respir Med. 8(7):717-725.
Niquini, R. P et al. (2020) SRAG por COVID-19 no Brasil: descrição e comparação de características demográficas e comorbidades com SRAG por influenza e com a população geral. Cadernos de Saúde Pública [online]. 36(7).
Oliveira J. O, Avelar V. R. T, Moita J. L. S, & Lima L. M. (2020) COVID-19: Fisiopatologia e Alvos para Intervenção Terapêutica de Almeida. Rev. Virtual Quim., 12 (6).
Oliveira, CD et al. (2010) Aspectos epidemiológicos de pacientes traqueostomizados em unidade de terapia intensiva adulto de um hospital de referência ao Sistema Único de Saúde em Belo Horizonte. Revista Brasileira de Terapia Intensiva [online]. 22(1).
Piazza C, Filauro M, Dikkers F. G, Nouraei S. A. R, Sandu K, Sittel C, Amin M. R, Campos G, Eckel H. E, & Peretti G. (2021) Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society. Eur Arch Otorhinolaryngol. 278(1):1-7.
Pradhan P, Mishra A. K, Mittal Y, Nayak A, Preetam C, Sarkar S, Samal D. K, & Parida P K. (2021) Tracheostomy in the COVID19 Patients: Our Experience in 12 Cases. Indian J Otolaryngol Head Neck Surg. 12:1-5.
Rosano A, et al. (2021) Early Percutaneous Tracheostomy in Coronavirus Disease 2019: Association With Hospital Mortality and Factors Associated With Removal of Tracheostomy Tube at ICU Discharge. A Cohort Study on 121 Patients. Critical Care Medicine. 49(2):261-270.
Safety and 30-day outcomes of tracheostomy for COVID-19: a prospective observational cohort study. Queen Elizabeth Hospital Birmingham COVID-19 airway team. British Journal of Anaesthesia. 2020, 125 (6): 872-879.
Saghazadeh A, & Rezaei N. (2020) Immune-epidemiological parameters of the novel coronavirus - a perspective. Expert Rev Clin Immunol. 16(5):465-470. 10.1080/1744666X.2020.1750954.
Sakae, T. M, Moretti G. R. F, Schmitz R. L, & Sakae D. Y. (2016) Comparação da mortalidade para traqueostomia precoce e tardia em pacientes cardiológicos de uma unidade de terapia intensiva no sul do Brasil. ACM arq. catarin. med. 45(1): 03-12.
Silva Junior, J. M., et al. (2010) Aplicabilidade do escore fisiológico agudo simplificado (SAPS 3) em hospitais brasileiros. Revista Brasileira de Anestesiologia [online]. 60(1), 20-31.
Tavares G S, Texeira A. P. A, & Faria I. D. (2018) Desmame prolongado da ventilação mecânica: revisão sistemática e proposição de um fluxograma de condução. Fisioterapia Brasil. 19(5), 711-722.
Tornari C, Surda P, Takhar A, Amin N, Dinham A, Harding R, Ranford DA, Archer SK, Wyncoll D, Tricklebank S, Ahmad I, Simo R, & Arora A. (2020) Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients. Eur Arch Otorhinolaryngol. 278(5):1595-1604.
Tornari C, Surda P, Takhar A, Amin N, Dinham A, Harding R, Ranford DA, Archer SK, Wyncoll D, Tricklebank S, Ahmad I, Simo R, & Arora A. (2021) Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients. Eur Arch Otorhinolaryngol. 278(5):1595-1604.
Zhang X, Huang Q, Niu X, et al. (2020) Manejo seguro e eficaz da traqueostomia em pacientes com COVID-19. Cabeça Pescoço. 42 (7): 1374-1381.
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