Antibiotic prophylaxis in oral and maxillofacial surgery: an integrative review
DOI:
https://doi.org/10.33448/rsd-v12i1.39898Keywords:
Antibiotics; Dentistry; Antimicrobials; Third molars.Abstract
Infections that occur during the perioperative period of oral and maxillofacial surgeries are recurrent complications of daily dental practice. The selected antibiotic must be bactericidal and effective against the most common microorganisms that cause infection associated with the procedure to be performed. In this sense, this study aimed to review the literature about antibiotic prophylaxis in oral and maxillofacial surgery. For the construction of this article, a bibliographical survey was carried out in the databases SciVerse Scopus, Scientific Electronic Library Online (Scielo), U.S. National Library of Medicine (PUBMED) and ScienceDirect, with the help of the Mendeley reference manager. The articles were contemplated between the years 2000 to 2022. The main results show that the use of prophylactic antibiotics can reduce the risk of SSI in more complex and larger procedures, such as head and neck cancer surgery. On the other hand, when it comes to dentoalveolar surgery, the literature is still not clear about the effectiveness of prophylaxis with antimicrobials. For removal of third molars, antibiotic therapy is of uncertain benefit for healthy patients, but no evidence was found for patients with pre-existing systemic conditions. Overall, a multitude of different regimens were administered regardless of the respective surgical procedure.
References
Adalarasan, S., Mohan, A., & Pasupathy, S. (2010). Prophylactic Antibiotics in Maxillofacial Fractures: A Requisite? Journal of Craniofacial Surgery, 21(4). https://journals.lww.com/jcraniofacialsurgery/Fulltext/2010/07000/Prophylactic_Antibiotics_in_Maxillofacial.15.aspx
Blatt, S., & Al-Nawas, B. (2019). A systematic review of latest evidence for antibiotic prophylaxis and therapy in oral and maxillofacial surgery. In Infection (Vol. 47, Issue 4). Springer Berlin Heidelberg. https://doi.org/10.1007/s15010-019-01303-8
Danda, A. K., & Ravi, P. (2011). Effectiveness of postoperative antibiotics in orthognathic surgery: a meta-analysis. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons, 69(10), 2650–2656. https://doi.org/10.1016/j.joms.2011.02.060
Danda, A. K., Wahab, A., Narayanan, V., & Siddareddi, A. (2010). Single-dose versus single-day antibiotic prophylaxis for orthognathic surgery: a prospective, randomized, double-blind clinical study. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons, 68(2), 344–346. https://doi.org/10.1016/j.joms.2009.09.081
Gaal, A., Bailey, B., Patel, Y., Smiley, N., Dodson, T., Kim, D., & Dillon, J. (2016). Limiting Antibiotics When Managing Mandible Fractures May Not Increase Infection Risk. Journal of Oral and Maxillofacial Surgery, 74(10), 2008–2018. https://doi.org/10.1016/j.joms.2016.05.019
Habib, A. M., Wong, A. D., Schreiner, G. C., Satti, K. F., Riblet, N. B., Johnson, H. A., & Ossoff, J. P. (2019). Postoperative prophylactic antibiotics for facial fractures: A systematic review and meta-analysis. Laryngoscope, 129(1), 82–95. https://doi.org/10.1002/lary.27210
Hansen, D., Pollan, L. D., & Fernando, H. (2013). Fulminant Clostridium difficile Colitis: A Complication of Perioperative Antibiotic Prophylaxis. Journal of Oral and Maxillofacial Surgery, 71(11), 1880–1885. https://doi.org/https://doi.org/10.1016/j.joms.2013.04.035
Kamolratanakul, P., & Jansisyanont, P. (2018). A review of antibiotic prophylaxis protocols in oral and maxillofacial surgery. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 30(5), 395–404. https://doi.org/https://doi.org/10.1016/j.ajoms.2018.03.008
Knepil, G. J., & Loukota, R. A. (2010). Outcomes of prophylactic antibiotics following surgery for zygomatic bone fractures. Journal of Cranio-Maxillofacial Surgery, 38(2), 131–133. https://doi.org/https://doi.org/10.1016/j.jcms.2009.03.015
Lang, M. S., Gonzalez, M. L., & Dodson, T. B. (2017). Do Antibiotics Decrease the Risk of Inflammatory Complications After Third Molar Removal in Community Practices? Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons, 75(2), 249–255. https://doi.org/10.1016/j.joms.2016.09.044
Lee, J. Y., Do, H. S., Lim, J. H., Jang, H. S., Rim, J. S., Kwon, J. J., & Lee, E. S. (2014). Correlation of antibiotic prophylaxis and difficulty of extraction with postoperative inflammatory complications in the lower third molar surgery. British Journal of Oral and Maxillofacial Surgery, 52(1), 54–57. https://doi.org/10.1016/j.bjoms.2013.08.010
López-Cedrún, J. L., Pijoan, J. I., Fernández, S., Santamaria, J., & Hernandez, G. (2011). Efficacy of Amoxicillin Treatment in Preventing Postoperative Complications in Patients Undergoing Third Molar Surgery: A Prospective, Randomized, Double-Blind Controlled Study. Journal of Oral and Maxillofacial Surgery, 69(6), e5–e14. https://doi.org/https://doi.org/10.1016/j.joms.2011.01.019
Milic, T., Raidoo, P., & Gebauer, D. (2021). Antibiotic prophylaxis in oral and maxillofacial surgery: a systematic review. British Journal of Oral and Maxillofacial Surgery, 59(6), 633–642. https://doi.org/10.1016/j.bjoms.2020.09.020
Mottini, M., Wolf, R., Soong, P. L., Lieger, O., Nakahara, K., & Schaller, B. (2014). The role of postoperative antibiotics in facial fractures: Comparing the efficacy of a 1-day versus a prolonged regimen. Journal of Trauma and Acute Care Surgery, 76(3). https://journals.lww.com/jtrauma/Fulltext/2014/03000/The_role_of_postoperative_antibiotics_in_facial.21.aspx
Pereira, A., Shitsuka, D., Parreira, F., & Shitsuka, R. (2018). Método Qualitativo, Quantitativo ou Quali-Quanti. In Metodologia da Pesquisa Científica. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1. Acesso em: 28 março 2020.
Perepa, A., Sinha, R., Agarwal, A., & Khan, T. A. (2018). Protocol for Antibiotic Administration in Mandibular Trauma: A Prospective Clinical Trial. Journal of Maxillofacial and Oral Surgery, 17(1), 19–23. https://doi.org/10.1007/s12663-016-0964-9
Sayd, S., Vyloppilli, S., Kumar, K., Subash, P., Kumar, N., & Raseel, S. (2018). Comparison of the efficacy of amoxicillin-clavulanic acid with metronidazole to azithromycin with metronidazole after surgical removal of impacted lower third molar to prevent infection. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 44(3), 103–106. https://doi.org/10.5125/jkaoms.2018.44.3.103
Tan, S. K., Lo, J., & Zwahlen, R. A. (2011). Perioperative antibiotic prophylaxis in orthognathic surgery: a systematic review and meta-analysis of clinical trials. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 112(1), 19–27. https://doi.org/10.1016/j.tripleo.2010.07.015
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Áquila de Oliveira Afonso; Felipe Rafael da Cunha Araújo; Anna Beatriz Luciano Alves; Evanio da Silva; Ana Claudia Cordeiro Alvarenga ; Genilson Campos da Silva; Anderson Dilly de Medeiros ; Débora Martins de Moura Lopes ; Tatiana Santos da Silva; Paulo Reis Lião Silva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.