Irrigating Solutions in Endodontics: evidence and deficiencies

Authors

DOI:

https://doi.org/10.33448/rsd-v12i3.40383

Keywords:

Endodontics; Chlorhexidine; Sodium hypochlorite.

Abstract

The aim of this study was to review the literature regarding irrigating solutions used in endodontic procedures, highlighting the most used ones and highlighting new alternatives for irrigating agents. The methodology was intended to perform an integrative literary review that was developed in six phases, namely: a) development of the research question; b) definition of descriptor terms and search platforms, c) definition of eligibility criteria used; d) careful analysis of the included studies; e) definition of the information to be extracted from the articles taken from the databases; f) interpretation of the results and presentation of the synthesis of knowledge, in which the guiding question was elaborated through the PICo strategy. Thus, bibliographical searches were carried out in the electronic portals PubMed, BVS and Ebsco using the keywords: Endodontics; Chlorhexidine and Sodium Hypochlorite, in which 22 articles were chosen for the development of this work. Sodium hypochlorite (NaOCl), ethylenediaminetetraacetic acid (EDTA) and chlorhexidine (CHX) are the most effective and safe irrigating solutions, with NaOCl and CHX being the most popular ones used. Thus, it is clear how important is the applicability of irrigating solutions during endodontic therapy. Because, through its administration, there is a positive response in the control of microbial agents that are found in the root canal. The sterilization of the root canal system is not possible and the available substances and techniques still have deficient points, due to this new irrigating solutions have been studied to add to endodontic interventions.

References

Alves, F. R. F., Marceliano-Alves, M. F., Souza, A. C., & Campello, A. F. (2020). Mucosal Fenestration After 2% Chlorhexidine Extrusion Used in Substitution of Sodium Hypochlorite: A Case Report. European journal of dentistry, 14(3), 511–516.

Arathi, G., Rajakumaran, A., Divya, S., Malathi, N., Saranya, V., & Kandaswamy, D. (2019). Comparison of penetrating depth of chlorhexidine and chitosan into dentinal tubules with and without the effect of ultrasonic irrigation. Journal of Oral and Maxillofacial Pathology: JOMFP, 23(3), 389.

Arruda-Vasconcelos, R., Barbosa-Ribeiro, M., Louzada, L. M., Mantovani, G. D., & Gomes, B. P. (2019). Apically extruded debris using passive ultrasonic irrigation associated with different root canal irrigants. Brazilian dental journal, 30, 363-367.

Bukhari, S., Kim, D., Liu, Y., Karabucak, B., & Koo, H. (2018). Novel endodontic disinfection approach using catalytic nanoparticles. Journal of endodontics, 44(5), 806-812.

El Sayed, M., Ghanerad, N., Rahimi, F., Shabanpoor, M., & Shabanpour, Z. (2020). Antibacterial activity of sodium hypochlorite gel versus different types of root canal medicaments using agar diffusion test: an in vitro comparative study. International Journal of Dentistry, 2020, 1-11.

El Sayed, M., Ghanerad, N., Shabanpour, Z., Shabanpoor, M., & Rahimi, F. (2021). Comparing the Antifungal Effect of Sodium Hypochlorite Gel versus Different Types of Root Canal Medicaments at Different Time Intervals Using the Agar Diffusion Test: An In Vitro Study. International journal of dentistry, 2021, 6550054.

Faras, F., Abo-Alhassan, F., Sadeq, A., & Burezq, H. (2016). Complication of improper management of sodium hypochlorite accident during root canal treatment. Journal of International Society of Preventive & Community Dentistry, 6(5), 493.

Fazelian, N., Dashtaki, A. R., Eftekharian, M., & Amiri, B. (2022). Influence of Chlorhexidine 2% and Sodium hypochlorite 5.25% on Micro-tensile Bond Strength of Universal adhesive system (G-Premio Bond). Brazilian Journal of Oral Sciences, 21.

Jing, X., Huang, X., Haapasalo, M., Shen, Y., & Wang, Q. (2019). Modeling oral multispecies biofilm recovery after antibacterial treatment. Scientific Reports, 9(1), 804.

Lockwood, C., Dos Santos, K. B., & Pap, R. (2019). Practical guidance for knowledge synthesis: Scoping review methods. Asian Nursing Research, 13(5), 287-294.

Luddin, N., & Ahmed, H. M. A. (2013). The antibacterial activity of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: A review on agar diffusion and direct contact methods. Journal of Conservative Dentistry: JCD, 16(1), 9.

Marek, E., Łagocka, R., Kot, K., Woźniak, K., & Lipski, M. (2020). A influência de duas formas de clorexidina na precisão dos localizadores apicais eletrônicos contemporâneos. BMC saúde bucal , 20 , 1-8.

Mooduto, L., Fredline, C., Sampoerno, G., Goenharto, S., Puteri, F. H., & Wahjuningrum, D. A. (2019). Cytotoxicity of sodium hypochlorite, chlorhexidine and propolis on human periodontal ligament fibroblast cell. Journal of International Dental and Medical Research, 12(2), 476-480.

Noites, R., Pina-Vaz, C., Rocha, R., Carvalho, M. F., Gonçalves, A., & Pina-Vaz, I. (2014). Synergistic antimicrobial action of chlorhexidine and ozone in endodontic treatment. BioMed research international, 2014.

Parisay, I., Talebi, M., Asadi, S., & Nikbakht, M. H. (2021). Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth. Journal of Dental Materials & Techniques, 10(2).

Pivatto, K., Pedro, FLM, Guedes, OA, Silva, AFD, Piva, E., Pereira, TM, ... & Borges, AH (2020). Citotoxicidade de agentes quelantes usados em endodontia e sua influência nas MMPs de membranas celulares. Revista odontológica brasileira , 31 , 32-36.

Retana-Lobo, C., Guerreiro-Tanomaru, J. M., Tanomaru-Filho, M., de Souza, B. D. M., & Reyes-Carmona, J. (2021). Sodium hypochlorite and chlorhexidine downregulate MMP expression on radicular dentin. Medical Principles and Practice, 30(5), 470-476.

Samiei, M., Shahi, S., Abdollahi, A. A., Eskandarinezhad, M., Negahdari, R., & Pakseresht, Z. (2016). The antibacterial efficacy of photo-activated disinfection, chlorhexidine and sodium hypochlorite in infected root canals: an in vitro study. Iranian endodontic journal, 11(3), 179.

Shadmehr, E., Davoudi, A., Sarmast, N. D., & Saatchi, M. (2019). Evaluation of antimicrobial efficacy of calcium hypochlorite as an endodontic irrigant on a mixed-culture biofilm: an ex vivo study. Iranian Endodontic Journal, 14(3), 178-184.

Srivastava, S., Singh Chhabra, H., Bhardwaj, K., Gupta, J., Vats, A., & Paliwal, A. (2014). Comparison Of Antimicrobial Efficacy Of Sodium Hypochlorite & Chlorhexidine At Different Concentrations-An Invitro Study. Indian Journal of Dental Sciences, 6(4).

Tandon, J., Taneja, S., Bhalla, V. K., & Jain, A. (2022). Evaluation of Bacterial Reduction at Various Stages of Endodontic Retreatment After Use of Different Disinfection Regimens: An In Vivo Study. European Endodontic Journal, 7(3), 210-216.

Teves, A., Blanco, D., Casaretto, M., Torres, J., Alvarado, D., & Jaramillo, DE (2019). Efetividade de diferentes técnicas de desinfecção do canal radicular na eliminação de biofilme multiespécie. Jornal de odontologia clínica e experimental , 11 (11), 978–983.

Tirali, R. E., Bodur, H., Sipahi, B., & Sungurtekin, E. (2013). Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro. Australian Endodontic Journal, 39(1), 15-18.

Whittemore, R., & Knafl, K. (2005). The integrative review: updated methodology. Journal of advanced nursing, 52(5), 546-553.

Published

18/02/2023

How to Cite

MESQUITA, K. B. N. de .; PEIXOTO, A. N. da S. .; GONÇALVES, L. A. B. .; CUNHA, C. F. E. da C. .; VIVACQUA, F. D. . Irrigating Solutions in Endodontics: evidence and deficiencies. Research, Society and Development, [S. l.], v. 12, n. 3, p. e3112340383, 2023. DOI: 10.33448/rsd-v12i3.40383. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/40383. Acesso em: 9 oct. 2024.

Issue

Section

Health Sciences