Correlation between urocultures and urine summary for the diagnosis of urinary tract infection in patients admitted to a university hospital in the state of Paraíba
Keywords:Urinary sediment analysis; Urinary tract infections; Nitrite; Pyuria.
Urinary tract infection (UTI) is one of the most frequent infections that affect patients in hospitals and can be classified as cystitis or pyelonephritis, depending on the site of infection. The diagnosis of UTI is basically made by performing the urine summary (EAS) and urine culture. Thus, the objective of this study was to conduct a retrospective study from January/2021 to December/2021 based on the database of the clinical analysis laboratory of the University Hospital Lauro Wanderley (HULW) in the state of Paraiba in relation to the alterations presented in the EAS exam, mainly with the markers nitrite and leukocyte esterase from positive urine cultures. The epidemiological data of these infections was also observed, as well as their bacterial incidence. A total of 1817 urine cultures were obtained, of which 837 had a request for EAS concomitantly, and of these 129 urine culture samples were positive, with the prevalent microorganisms being Escherichia coli (36.5%), Klebsiella pneumoniae (20.6 %) and Pseudomonas aeruginosa (8.7%). Nitrite was observed in 16% of the samples and leukocyte esterase in 58%. We conclude that regarding the results of the EAS, leukocyturia proved to be a more sensitive marker to aid in the diagnosis of UTI compared to nitrite, corroborating the specialized scientific literature, with a predominance of UTI in female patients.
Alves, A. R. D. M. S. (2018). Estratégias profiláticas da infeção urinária recorrente não complicada na mulher adulta saudável (tese de doutorado). Universidade do Porto, Portugal.
Blatt, J. M., & Miranda, M. C. (2005). Perfil dos microrganismos causadores de infecções do trato urinário em pacientes internados. Revista panamericana de Infectologia, 9(4), 10-14.
Bortolotto, L. A., Indras, D. M., Silva, C. M., & Peder, L. D. (2016). Presença de analitos químicos e microscópicos na urina e sua relação com infecção urinária. Revista Saúde, 42(2), 89-96.
Castro, B. G. (2019). Prevalência de bactérias Gram-positivas em infecção do trato urinário. Revista Brasileira de Análises clínicas, 51(4), 322-337.
Chaves, N. M. O., & Moraes, C. L. K. (2015). Control of infection in urinary catheterization in an intensive care unit. Revista de Enfermagem do Centro Oeste Mineiro, 5(2), 1650-1657.
Cristea, O. M., Avrămescu, C. S., Bălășoiu, M., Popescu, F. D., Popescu, F., & Amzoiu, M. O. (2017). Urinary tract infection with Klebsiella pneumoniae in Patients with Chronic Kidney Disease. Curr Health Sci J, 43(2), 137-148.
Furlan, A. P. F., Pereira, R. R. S., Xavier, R. A., & Lima, T. S. (2021). Prevalência e perfil de resistência bacteriana nas infecções do trato urinário em hospitais da região norte e nordeste do Brasil: uma revisão. Brazilian Journal of Health Review, 4(2), 9244-9256.
Henry, J. B., Lauzon, R. B., & Schumann, G. B. (1996). Basic Examination of urine. In: Henry JB, editor. Clinical diagnosis and management by laboratory methods. Philadelphia, WB Saunders; p. 411-456.
Klein, R. D., & Hultgren, S. J. (2020). Urinary tract infections: microbial pathogenesis, host-pathogen interactions, and new treatment strategies. Nature Reviews Microbiology, 18(4), 211-226.
Koche, J. C. (2011). Fundamentos de metodologia científica. Petrópolis: Vozes. http://www.brunovivas.com/wp content/uploads/sites/10/2018/07/K%C3%B6che-Jos%C3%A9-
Masson, L.C., Ferreira, A.L., Oliveira, A.F., Barcellos, R. B., Carvalho, A.L., Silva, G. A., ... & Oliveira, R. A. (2020). Diagnóstico laboratorial das infecções urinárias: relação entre a urocultura e o EAS. Revista Brasileira de Análises Clínicas, 52(1), 77-81.
Miranda, A. L., Oliveira, A. L. L., Nacer, D. T., & Aguiar, C. A. M. (2016). Results after implementation of a protocol on the incidence of urinary tract infection in an intensive care unit. Revista Latino-Americana de Enfermagem, 24. doi:10.1590/1518-8345.0866.2804.
Ngong, I. J., Etongwe, E., Atashili, J., Akoachere, J. F. T. K., & Ndumbe, P. M. (2021). Prevalence, antimicrobial susceptibility pattern and associated risk factors for urinary tract infections in pregnant women attending ANC in some integrated health centers in the Buea Health District. BMC Pregnancy and Childbirth, 21(1), 673.
Nys, S., van Merode, T., Bartelds, A. I., & Stobberingh, E. E. (2006). Urinary tract infections in general practice patients: diagnostic tests versus bacteriological culture. Journal of Antimicrobial Chemotherapy, 57(5), 955-958.
Oliveira, M. S., Cardoso, R. S., Santos, J. S., Vasconcelos, J. R., & Souza, M. C. (2021). Principais bactérias encontradas em uroculturas de pacientes com Infecções do Trato Urinário (ITU) e seu perfil de resistência frente aos antimicrobianos. Research, Society and Development, 10(7), e5310716161-e 5310716161.
Ringsrud, K. M., & Linné, J. J. (1995). Chemical examination of urine. In: Ringsrud, K. M. & Linné, J. J. (1995). Urinalysis and body fluids: a color text and atlas. St. Louis (USA): Mosby, p.43-80.
Roriz-Filho, J. S., Oliveira, L. A., Amaral, C. F. S., & Guimarães, P. M. R. (2010). Infecção do trato urinário. Medicina (Ribeirão Preto), 43(2), 118-125.
Guido, S., Eberhardt, K., Klaus, G., Martha, M. M., & Eva, H. P. (2010). The Diagnosis of Urinary Tract Infection. Dtsch Arztebl Int, 107(21), 361-367.
How to Cite
Copyright (c) 2023 Viviane Araújo Silva; Brenda Kettinly Ferreira Souza; Larissa Rodrigues dos Santos Silva; Ana Paloma Tavares de Araújo; Francisco Cunha Nunes; Humberto de Carvalho Aragão Neto; Nathalia de Alencar Cunha Tavares
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.