3D printing applied to health

Authors

DOI:

https://doi.org/10.33448/rsd-v12i6.41975

Keywords:

3D printing; Health; Prostheses; Surgical planning; Education; 3D bioprinting.

Abstract

3D printing, also known as additive manufacturing, is a technology that has existed since the 1980s. 3D printing can be applied to health in several ways: production of didactic material in the area of health, prostheses, surgical planning and with bioprinting of organs. There are several methodologies used for 3D printing applied to health, but basically they follow the process: idealization of the model, conversion of the file into STL, then G-Code and then printing and treatment of the printed object. The printers can use plastic, biodegradable material, powders, liquid or even living cells. The objective of this study is to show in a simplified way how 3D printing can be applied to health, addressing the main concepts of 3D printing. To carry out the article, a search was made for scientific articles from 2010-2023 with the theme 3D printing applied to health. This study showed that, since the 1980s, 3D printing has improved a lot, but challenges such as costs, production time and regulatory mechanisms still need to be overcome.

References

Awad, A., Fina, F., Goyanes, A., Gaisford, S., & Basit, A. W. (2021). Advances in powder bed fusion 3D printing in drug delivery and healthcare. Advanced Drug Delivery Reviews, 174, 406-424.

Beitler, B. G., Abraham, P. F., Glennon, A. R., Tommasini, S. M., Lattanza, L. L., Morris, J. M., et al. (2022). Interpretation of regulatory factors for 3D printing at hospitals and medical centers, or at the point of care. 3D Printing in Medicine, 8(1), 7.

Chung, J. J., Im, H., Kim, S. H., Park, J. W., & Jung, Y. (2020). Toward biomimetic scaffolds for tissue engineering: 3D printing techniques in regenerative medicine. Frontiers in Bioengineering and Biotechnology, 8, 586406.

Culmone, C., Henselmans, P. W., van Starkenburg, R. I., & Breedveld, P. (2020). Exploring non-assembly 3D printing for novel compliant surgical devices. Plos one, 15(5), e0232952.

De La Peña, A., De La Peña-Brambila, J., Pérez-De La Torre, J., Ochoa, M., & Gallardo, G. J. (2018). Low-cost customized cranioplasty using a 3D digital printing model: a case report. 3D Printing in Medicine, 4, 1-9.

Debnath, S. K., Debnath, M., Srivastava, R., & Omri, A. (2021). Intervention of 3D printing in health care: transformation for sustainable development. Expert opinion on drug delivery, 18(11), 1659-1672.

Elkasabgy, N. A., Mahmoud, A. A., & Maged, A. (2020). 3D printing: An appealing route for customized drug delivery systems. International Journal of Pharmaceutics, 588, 119732.

Eshkalak, S. K., Ghomi, E. R., Dai, Y., Choudhury, D., & Ramakrishna, S. (2020). The role of three-dimensional printing in healthcare and medicine. Materials & Design, 194, 108940.

Ford, S., & Minshall, T. (2019). Invited review article: Where and how 3D printing is used in teaching and education. Additive Manufacturing, 25, 131-150.

Funk, N. L., Fantaus, S., & Beck, R. C. R. (2022). Immediate release 3D printed oral dosage forms: how different polymers have been explored to reach suitable drug release behaviour. International Journal of Pharmaceutics, 122066.

George, M., Aroom, K. R., Hawes, H. G., Gill, B. S., & Love, J. (2017). 3D printed surgical instruments: the design and fabrication process. World journal of surgery, 41, 314-319.

Goole, J., & Amighi, K. (2016). 3D printing in pharmaceutics: A new tool for designing customized drug delivery systems. International journal of pharmaceutics, 499(1-2), 376-394.

Gungor-Ozkerim, P. S., Inci, I., Zhang, Y. S., Khademhosseini, A., & Dokmeci, M. R. (2018). Bioinks for 3D bioprinting: an overview. Biomaterials science, 6(5), 915-946.

Hao, Y., Wang, L., Jiang, W., Wu, W., Ai, S., Shen, L., et al. (2020). 3D printing hip prostheses offer accurate reconstruction, stable fixation, and functional recovery for revision total hip arthroplasty with complex acetabular bone defect. Engineering, 6(11), 1285-1290.

Haryńska, A., Carayon, I., Kosmela, P., Szeliski, K., Łapiński, M., Pokrywczyńska, M., et al. (2020). A comprehensive evaluation of flexible FDM/FFF 3D printing filament as a potential material in medical application. European Polymer Journal, 138, 109958.

Huang, W., & Zhang, X. (2014). 3D printing: print the future of ophthalmology. Investigative ophthalmology & visual science, 55(8), 5380-5381.

Kirillova, A., Bushev, S., Abubakirov, A., & Sukikh, G. (2020). Bioethical and legal issues in 3D bioprinting. International Journal of Bioprinting, 6(3).

Liacouras, P. C., Sahajwalla, D., Beachler, M. D., Sleeman, T., Ho, V. B., & Lichtenberger, J. P. (2017). Using computed tomography and 3D printing to construct custom prosthetics attachments and devices. 3D printing in medicine, 3, 1-7.

Morrison, R. J., Kashlan, K. N., Flanangan, C. L., Wright, J. K., Green, G. E., Hollister, S. J., et al. (2015). Regulatory considerations in the design and manufacturing of implantable 3D‐printed medical devices. Clinical and translational science, 8(5), 594-600.

Msallem, B., Sharma, N., Cao, S., Halbeisen, F. S., Zeilhofer, H.-F., & Thieringer, F. M. (2020). Evaluation of the dimensional accuracy of 3D-printed anatomical mandibular models using FFF, SLA, SLS, MJ, and BJ printing technology. Journal of clinical medicine, 9(3), 817.

Murphy, S. V., & Atala, A. (2014). 3D bioprinting of tissues and organs. Nature biotechnology, 32(8), 773-785.

Murphy, S. V., De Coppi, P., & Atala, A. (2020). Opportunities and challenges of translational 3D bioprinting. Nature biomedical engineering, 4(4), 370-380.

Ozbolat, I. T., Peng, W., & Ozbolat, V. (2016). Application areas of 3D bioprinting. Drug discovery today, 21(8), 1257-1271.

Palo, M., Holländer, J., Suominen, J., Yliruusi, J., & Sandler, N. (2017). 3D printed drug delivery devices: perspectives and technical challenges. Expert review of medical devices, 14(9), 685-696.

Park, G.-S., Kim, S.-K., Heo, S.-J., Koak, J.-Y., & Seo, D.-G. (2019). Effects of printing parameters on the fit of implant-supported 3D printing resin prosthetics. Materials, 12(16), 2533.

Ricles, L. M., Coburn, J. C., Di Prima, M., & Oh, S. S. (2018). Regulating 3D-printed medical products. Science translational medicine, 10(461), eaan6521.

Shahrubudin, N., Lee, T. C., & Ramlan, R. (2019). An overview on 3D printing technology: Technological, materials, and applications. Procedia Manufacturing, 35, 1286-1296.

Sheha, E. D., Gandhi, S. D., & Colman, M. W. (2019). 3D printing in spine surgery. Annals of translational medicine, 7(Suppl 5).

Tan, Y. J. N., Yong, W. P., Kochhar, J. S., Khanolkar, J., Yao, X., Sun, Y., et al. (2020). On-demand fully customizable drug tablets via 3D printing technology for personalized medicine. Journal of Controlled Release, 322, 42-52.

Ventola, C. L. (2014). Medical applications for 3D printing: current and projected uses. Pharmacy and Therapeutics, 39(10), 704.

Xu, X., Awad, A., Robles-Martinez, P., Gaisford, S., Goyanes, A., & Basit, A. W. (2021). Vat photopolymerization 3D printing for advanced drug delivery and medical device applications. Journal of Controlled Release, 329, 743-757.

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Published

03/06/2023

How to Cite

PACHECO, T. J. A. .; VIEIRA, A. C. A. .; MENEZES, L. S. .; BRANDÃO, V. P. .; COSTA, N. B. M. .; SOUZA, D. G. de. 3D printing applied to health. Research, Society and Development, [S. l.], v. 12, n. 6, p. e2512641975, 2023. DOI: 10.33448/rsd-v12i6.41975. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/41975. Acesso em: 3 may. 2024.

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Section

Health Sciences