Obesity and childhood diabetes as aggravating conditions of COVID-19 in children in the West of Paraná

Authors

DOI:

https://doi.org/10.33448/rsd-v12i6.42149

Keywords:

COVID-19; Obesity; Diabetes; Pediatrics.

Abstract

COVID-19, a respiratory illness caused by the SARS-CoV-2 coronavirus, has been a global concern due to its strength and impact on public health. The virus spreads mainly through respiratory droplets, when an infected person coughs, sneezes or talks, but it can also be acquired through contact with contaminated surfaces. When in the human body, it enters the lungs through the enzyme ECA2.This study aimed to investigate whether there is a higher incidence of severe cases of COVID-19 in obese and/or diabetic children compared to healthy children. For this, a quantitative, observational and cross-sectional study was carried out using data provided by the Division of Epidemiological Surveillance of Cascavel, involving pediatric patients up to 12 years old.The results of the analysis of COVID-19 cases in children revealed that the incidence of severe cases was significantly higher in children with diabetes and/or obesity. This finding suggests an association between obesity/diabetes and greater severity of COVID-19 infection in children.These findings are important for public health and highlight the need for specific policies and interventions to prevent and treat obesity and diabetes in children. In addition, they highlight the importance of preventive measures, such as vaccination, to protect children against COVID-19 and reduce the risk of serious complications.

References

Andrade, M., Lamounier, J., Paiva, T., Leite, P., & Silva, E. (2021). Lethality by COVID-19 in children: an integrative review. Residência Pediátrica, 11(1). https://doi.org/10.25060/residpediatr-2021.v11n1-421

Andrade, P. M. de, Barbosa, S. C. S., Malta, V. F. M., Silva, P. H. A. da, Malta, R. W. P., Galindo, V. de A., & Dantas, V. de G. L. (2020). A influência da variação da expressão de ACE2 na severidade da COVID-19 em adultos e crianças: uma revisão sistemática/ The variation of ACE2 expression influence in the severity of COVID-19 in adults and children: a systematic review. Brazilian Applied Science Review, 4(6), 3792–3804. https://doi.org/10.34115/basrv4n6-039

Blanco Hidalgo, O. (2004). Propiedades antiinflamatorias del surfactante pulmonar y su aplicación en la clínica. Biotecnología Aplicada, 21(2), 70–76. https://biblat.unam.mx/pt/revista/biotecnologia-aplicada/articulo/propiedades-antiinflamatorias-del-surfactante-pulmonar-y-su-aplicacion-en-la-clinica

Brandão, S. C. S., Godoi, E. T. A., Cordeiro, L. H. de O., Bezerra, C. S., Ramos, J. de O. X., Arruda, G. F. A. de, & Lins, E. M. (2020, July 1). Obesidade e risco de Covid-19 : grave. Repositorio.ufpe.br. https://repositorio.ufpe.br/handle/123456789/37572

Calliari, L. E., Almeida, F. J., & Noronha, R. M. (2020). Infections in children with diabetes. Jornal de Pediatria, 96, 39–46. https://doi.org/10.1016/j.jped.2019.09.004

Chao, J. Y., Derespina, K. R., Herold, B. C., Goldman, D. L., Aldrich, M., Weingarten, J., Ushay, H. M., Cabana, M. D., & Medar, S. S. (2020). Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 (COVID-19) at a Tertiary Care Medical Center in New York City. The Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2020.05.006

di Palmo, E., Filice, E., Cavallo, A., Caffarelli, C., Maltoni, G., Miniaci, A., Ricci, G., & Pession, A. (2021). Childhood Obesity and Respiratory Diseases: Which Link? Children, 8(3), 177. https://doi.org/10.3390/children8030177

Diabesidade - O que é isso e porque é considerado uma epidemia. (2019, March 27). SBCBM. https://www.sbcbm.org.br/diabesidade-o-que-e-isso-e-porque-e-considerado-uma-epidemia/#:~:text=Esse%20tipo%20de%20diabetes%20

Dunachie, S., & Chamnan, P. (2018). The double burden of diabetes and global infection in low and middle-income countries. Transactions of the Royal Society of Tropical Medicine and Hygiene, 113(2), 56–64. https://doi.org/10.1093/trstmh/try124

Estrela, C. (2018). Metodologia Científica. Artes Medicas.

Lopez, Fabio Ancona., Campos Junior, Dioclécio. & De, B. (2010). Tratado de pediatria. Manole.

Fonseca-Alaniz, M. H., Takada, J., Alonso-Vale, M. I. C., & Lima, F. B. (2007). O tecido adiposo como órgão endócrino: da teoria à prática. Jornal de Pediatria, 83(5), S192–S203. https://doi.org/10.1590/s0021-75572007000700011

IBGE | censo 2010 | resultados | notícias. (2006). Censo2010.Ibge.gov.br. https://encurtador.com.br/cAEFV

Pereira, J. (2018). Manual de metodologia da pesquisa científica. Atlas.

Liu, M., Wang, T., Zhou, Y., Zhao, Y., Zhang, Y., & Li, J. (2020). Potential role of ACE2 in coronavirus disease 2019 (COVID-19) prevention and management. Journal of Translational Internal Medicine, 8(1), 9–19. https://doi.org/10.2478/jtim-2020-0003

Mastrorilli, C., Posa, D., Cipriani, F., & Caffarelli, C. (2016). Asthma and allergic rhinitis in childhood: what’s new. Pediatric Allergy and Immunology, 27(8), 795–803. https://doi.org/10.1111/pai.12681

Mello, E. D. de, Luft, V. C., & Meyer, F. (2004). Childhood obesity - Towards effectiveness. Jornal de Pediatria, 80(3), 173–182. https://doi.org/10.2223/jped.1180

Menegon, R., Silva, W. G. da, & Sousa, P. M. L. S. de. (2022). Obesidade infantil: medidas de prevenção. Research, Society and Development, 11(13), e304111335512. https://doi.org/10.33448/rsd-v11i13.35512

Ministério da Saúde. (2020). Coronavírus Brasil. Covid.saude.gov.br. https://covid.saude.gov.br/

Nove, U., Brasil, J., Dias, L., Maciel, C., Regina, T., & Sablich. (2009). ConScientiae Saúde. https://www.redalyc.org/pdf/929/92960109.pdf

Oliveira, C. L. de, & Fisberg, M. (2003). Obesidade na infância e adolescência: uma verdadeira epidemia. Arquivos Brasileiros de Endocrinologia & Metabologia, 47(2), 107–108. https://doi.org/10.1590/s0004-27302003000200001

Pillar, G., & Shehadeh, N. (2008). Abdominal Fat and Sleep Apnea: The chicken or the egg? Diabetes Care, 31(Supplement 2), S303–S309. https://doi.org/10.2337/dc08-s272

Prata-Barbosa, A., Lima-Setta, F., Santos, G. R. dos, Lanziotti, V. S., Castro, R. E. V. de, Souza, D. C. de, Raymundo, C. E., Oliveira, F. R. C. de, Lima, L. F. P. de, Tonial, C. T., Colleti Jr. , J., Bellinat, A. P. N., Lorenzo, V. B., Zeitel, R. de S., Pulcheri, L., Costa, F. C. M. da, La Torre, F. P. F., Figueiredo, E. A. das N., Silva, T. P. da, & Riveiro, P. M. (2020). Pacientes pediátricos com COVID-19 admitidos em Unidades de Terapia Intensiva no Brasil: um estudo prospectivo multicêntrico. Jornal de Pediatria, 96, 582–592. https://doi.org/10.1016/j.jped.2020.07.002

Safadi, M. A. P. (2020). The intriguing features of COVID-19 in children and its impact on the pandemic. Jornal de Pediatria. https://doi.org/10.1016/j.jped.2020.04.001

Santos, A. C. G., Junior, R. C. S., Santana, I. A. de O., Sousa, D. S. de, Souza, C. S. de, Jesus, C. V. F. de, & Lima, S. O. (2021). Obesidade infantil e doenças respiratórias: uma perigosa associação. Revista Eletrônica Acervo Saúde, 13(5), e7443. https://doi.org/10.25248/reas.e7443.2021

Santos, F., Fernandes, P., & Ramos, M. (2021). Enzima TMPRSS2. Revista de Ciência Elementar, 9(4). https://doi.org/10.24927/rce2021.065

Shekerdemian, L. S., Mahmood, N. R., Wolfe, K. K., Riggs, B. J., Ross, C. E., McKiernan, C. A., Heidemann, S. M., Kleinman, L. C., Sen, A. I., Hall, M. W., Priestley, M. A., McGuire, J. K., Boukas, K., Sharron, M. P., & Burns, J. P. (2020). Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatrics. https://doi.org/10.1001/jamapediatrics.2020.1948

Smiderle, L., Lazzaretti, C., Maiara, M., & Lopes, S. (2020). A expressão de receptores ECA2 e a progressão da Covid-19 em crianças Autor(es). https://moexp.osorio.ifrs.edu.br/uploads/anai/2020/Anais%20MoExP%202020%20Etapa%20II.1799.pdf

Wajchenberg, B. L. (2000). Tecido adiposo como glândula endócrina. Arquivos Brasileiros de Endocrinologia & Metabologia, 44(1), 13–20. https://doi.org/10.1590/s0004-27302000000100004

WHO. (2021, June 9). Obesity and Overweight. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight

Published

15/06/2023

How to Cite

SOUZA, N. G. de .; FIORI, C. M. C. M. . Obesity and childhood diabetes as aggravating conditions of COVID-19 in children in the West of Paraná. Research, Society and Development, [S. l.], v. 12, n. 6, p. e14612642149, 2023. DOI: 10.33448/rsd-v12i6.42149. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/42149. Acesso em: 3 may. 2024.

Issue

Section

Health Sciences