PRF in orofacial harmonization: a narrative review of the literature
DOI:
https://doi.org/10.33448/rsd-v12i6.42230Keywords:
Platelet-Rich Fibrin; Rejuvenation; Collagen.Abstract
The search for rejuvenation is a prevalent desire in today's society, driven by technological advances in the health area, which has provided the emergence of new techniques to improve aesthetics. The face, where individual characteristics are expressed, is composed of complex layers of tissue, the skin being the largest organ, composed of epidermis, dermis and hypodermis. With aging, there is loss of subcutaneous fat and reduction of dermal collagen, resulting in furrows and facial depressions. To combat these effects, the use of platelet-rich fibrin (PRF) has been widely studied, offering benefits for the skin. PRF has tissue regeneration potential, is biocompatible and has an affordable clinical cost. In orofacial harmonization, the purpose of PRF is to restore or regulate the cellular activity responsible for skin remodeling, reversing the effects of dermal aging. Its autologous composition, rich in growth factors and plasma proteins, provides a natural and effective approach. In addition, PRF releases growth factors in a prolonged way, enhancing regenerative effects and accelerated healing. Its application by qualified professionals, using specific techniques, has shown positive results in the reduction of wrinkles, fine lines and general improvement of the skin. PRF has advantages over other approaches such as PRP, including reduced cost and lower risk of immunogenic reactions and disease transmission. Thus, the objective of this article is to carry out a narrative review of the literature on the application of PRF in orofacial harmonization.
References
Carvalho, N. A., Morais, C. E. C., Nascimento, F, Dietrich, L., Costa, M. D. M. de A. (2021). Applicability of PRF- platelet-rich fibrin in Dentistry and it’s benefits. Research, Society and Development, 10(13): e466101321570.
Cavallo, C., Roffi, A., Grigolo, B., Mariani, E., Pratelli, L., Merli, G., Kon, E., Marcacci, M., & Filardo, G. (2016). Platelet-Rich Plasma: The Choice of Activation Method Affects the Release of Bioactive Molecules. BioMed research international, 2016, 6591717.
Cieslik-Bielecka, A., Dohan Ehrenfest, D. M., Lubkowska, A., & Bielecki, T. (2012). Microbicidal properties of Leukocyte- and Platelet-Rich Plasma/Fibrin (L-PRP/L-PRF): new perspectives. Journal of biological regulators and homeostatic agents, 26(2 Suppl 1), 43S–52S.
Dohan Ehrenfest, D. M., Rasmusson, L., & Albrektsson, T. (2009). Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends in biotechnology, 27(3), 158–167.
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J., Mouhyi, J., & Gogly, B. (2006). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 101(3), e45–e50.
Donadussi, M. (2012). Revisão sistemática da literatura sobre a efetividade clínica do plasma rico em plaquetas para o tratamento dermatológico estético. Pontifícia Universidade Católica do Rio Grande do Sul, 1(1).
Everts, P., Onishi, K., Jayaram, P., Lana, J. F., & Mautner, K. (2020). Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020. International journal of molecular sciences, 21(20), 7794.
Falcão, L. R. M., Rocha, S. M. W., Mota, K. R., Malta, T. A. J., Rios, R. A. A., Fernandes, K. J. de M., et al. (2021). Use of platelet-rich fibrin in aesthetics and facial rejuvenation: Integrative review. Research, Society and Development, 10(9):e19610917676.
Ghanaati, S., Booms, P., Orlowska, A., et al. (2014). Fibrina rica em plaquetas avançada: um novo conceito para engenharia de tecidos baseada em células por meio de células inflamatórias. J Oral Implantol, 40(6):679–89.
Gupta, S., Paliczak, A., & Delgado, D. (2021). Evidence-based indications of platelet-rich plasma therapy. Expert review of hematology, 14(1), 97–108.
Karimi, K., & Rockwell, H. (2019). The Benefits of Platelet-Rich Fibrin. Facial plastic surgery clinics of North America, 27(3), 331–340.
Mann, K. G., Brummel, K., & Butenas, S. (2003). What is all that thrombin for? Journal of thrombosis and haemostasis : JTH, 1(7), 1504–1514.
Masuki, H., Okudera, T., Watanebe, T., Suzuki, M., Nishiyama, K., Okudera, H., Nakata, K., Uematsu, K., Su, C. Y., & Kawase, T. (2016). Growth factor and pro-inflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factors (PRGF), advanced platelet-rich fibrin (A-PRF), and concentrated growth factors (CGF). International journal of implant dentistry, 2(1), 19.
Mescher, A. L. (2013). Sangue. Em: Texto e atlas de histologia básica de Junqueira. (15a ed.). McGraw-Hill.
Miron, R. J., Zucchelli, G., Pikos, M. A., Salama, M., Lee, S., Guillemette, V., Fujioka-Kobayashi, M., Bishara, M., Zhang, Y., Wang, H. L., Chandad, F., Nacopoulos, C., Simonpieri, A., Aalam, A. A., Felice, P., Sammartino, G., Ghanaati, S., Hernandez, M. A., & Choukroun, J. (2017). Use of platelet-rich fibrin in regenerative dentistry: a systematic review. Clinical oral investigations, 21(6), 1913–1927.
Naik, B., Karunakar, P., Jayadev, M., & Marshal, V. R. (2013). Role of Platelet rich fibrin in wound healing: A critical review. Journal of conservative dentistry: JCD, 16(4), 284–293.
Narang, I., Mittal, N., & Mishra, N. (2015). A comparative evaluation of the blood clot, platelet-rich plasma, and platelet-rich fibrin in regeneration of necrotic immature permanent teeth: A clinical study. Contemporary clinical dentistry, 6(1), 63–68.
Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253–258.
Rittié, L., & Fisher, G. J. (2015). Natural and sun-induced aging of human skin. Cold Spring Harbor perspectives in medicine, 5(1), a015370.
Rother, E. T. (2007). Revisão sistemática x revisão narrativa. Acta Paul. Enferm, 20(2).
Utomo, D. N., Mahyudin, F., Hernugrahanto, K. D., Suroto, H., Chilmi, M. Z., & Rantam, F. A. (2018). Implantation of platelet rich fibrin and allogenic mesenchymal stem cells facilitate the healing of muscle injury: An experimental study on animal. Int J Surg Open. 11:4-9.
Velnar, T., Bailey, T., & Smrkolj, V. (2009). The wound healing process: an overview of the cellular and molecular mechanisms. The Journal of international medical research, 37(5), 1528–1542.
Wu, P. I., Diaz, R., & Borg-Stein, J. (2016). Platelet-Rich Plasma. Physical medicine and rehabilitation clinics of North America, 27(4), 825–853.
Zins, J. E., Grow, J., & Cakmakoglu, C. (2022). Brow Anatomy and Aesthetics of the Upper Face. Clinics in plastic surgery, 49(3), 339–348.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Luiza Siniscalchi Soares; Roberto Teruo Suguihara; Daniella Pilon Muknicka
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
